AHK-Cu (Copper Tripeptide)
A copper-binding tripeptide studied for hair growth stimulation and follicle health.
Overview
AHK-Cu (alanine-histidine-lysine copper complex) is a tripeptide-copper complex related to GHK-Cu. It has been specifically studied for hair growth stimulation, showing ability to increase hair follicle size and promote the anagen (growth) phase of the hair cycle.
The following information summarizes peer-reviewed research on AHK-Cu (Copper Tripeptide). Study descriptions reflect published findings, e.g., "animal studies have investigated," "cellular studies suggest," or "clinical trials have evaluated", and do not constitute therapeutic claims.
Mechanism of Action
AHK-Cu stimulates hair follicle growth by increasing the expression of VEGF around hair follicles, promoting vascularization of the dermal papilla. It also upregulates FGF-7 and Wnt signaling pathways involved in hair follicle morphogenesis and cycling.
Research Evidence
AHK-Cu (Copper Tripeptide). Evidence Summary
No peer-reviewed studies have been indexed for this compound
Evidence Level 1: Early Research, Very limited published research. May include only 1–2 preliminary laboratory or theoretical studies.
Study Type Distribution
38
Human Studies
103
Animal Studies
0
In Vitro
59
Reviews
200
Last 5 Years
200
Last 10 Years
53974
Total Indexed Studies
Research Coverage
Last PubMed Ingestion
…
Research Timeline
Chronological progression of AHK-Cu (Copper Tripeptide) research, auto-generated from 3 indexed publications.
Pyo et al. (2007). Demonstrated hair growth promotion by copper tripeptides.
Research on AHK-Cu (Copper Tripeptide)
Fischer et al. (2010). Comparative copper peptide efficacy in hair biology.
Research on AHK-Cu (Copper Tripeptide)
Kang et al. (2012). Showed VEGF and follicle size increases with AHK-Cu treatment.
Research on AHK-Cu (Copper Tripeptide)
Conditions Studied
Back Pain
33 peptides studied
Hair Growth
40 peptides studied
Skin Repair
38 peptides studied
Wound Healing
46 peptides studied
Cardiovascular Health
31 peptides studied
Liver Health
21 peptides studied
Angiogenesis
32 peptides studied
Collagen Production
31 peptides studied
Growth Hormone Deficiency
90 peptides studied
Research Studies
AHK-Cu (Copper Tripeptide) research — Pyo, H
Pyo, H
K. et al. J Peptide Science, 2007
Referenced study on AHK-Cu (Copper Tripeptide) investigating hair growth and regeneration.
AHK-Cu (Copper Tripeptide) research — Kang, J
Kang, J
I. et al. Skin Pharmacology, 2012
Referenced study on AHK-Cu (Copper Tripeptide) investigating hair growth and regeneration.
Study Highlights
Study summaries are being curated for AHK-Cu (Copper Tripeptide).
Further Reading
Scientific Context
This page summarizes published scientific research on AHK-Cu (Copper Tripeptide). Many peptides discussed on this site are experimental research compounds that have not been approved for clinical use. The research presented here is sourced from peer-reviewed journals and indexed databases such as PubMed. Evidence levels and study counts reflect the quantity and type of available research, not efficacy or safety endorsements.
This content is for educational and informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before making any health-related decisions.
Learn about our editorial standards →Research Transparency
PSI functions as a transparent research index. All research information is sourced from peer-reviewed scientific literature and automatically indexed from PubMed/MEDLINE. Every study displayed includes verifiable source references. PubMed ID, journal, authors, and publication year, allowing independent verification. PSI does not make therapeutic claims; all content summarizes published research findings.
Looking for a physician who prescribes this peptide? Browse the PSI physician directory →
Published: January 15, 2025
Updated: March 1, 2026
This content is for educational and research purposes only. It is not intended as medical advice, diagnosis, or treatment. Consult a qualified healthcare provider before making any health decisions.