Research Index
Vesugen Research Index
PSI surfaces 50 peer-reviewed studies on Vesugen, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
50 studies
Recommended sleep duration is associated with greater parasympathetic regulation in patients with hypertension.
Nakayama N, Moriwaki Y, Tamakoshi K et al.
Sleep Biol Rhythms·2026·Human·PubMed →
Melatonin to improve sleep in patients undergoing major surgery: protocol for a double-blind, randomised placebo-controlled trial (MELROSE).
Martinez FE, Lott N, Tarrant S et al.
BMJ Open·2026·Human·Sleep·PubMed →
Salivary Melatonin and MMP-9 Levels in Stage III Periodontitis: A Pilot Study Using Standardized Pre-Sleep Saliva Collection.
Ivanov I, Naseva E, Mlachkova A et al.
Medicina (Kaunas)·2026·Human·PubMed →
Association between chronotype preference and sleep characteristics in insomnia patients.
Wang Y, Dong M, Zhao X et al.
Sleep Breath·2026·Human·PubMed →
Effect of traditional Chinese medicine on sleep and blood pressure in patients with comorbid hypertension-insomnia: a systematic review and meta-analysis.
Fan Y, Li H, Ma Y et al.
Front Psychiatry·2026·Human·PubMed →
Intrinsically Photosensitive Retinal Ganglion Cell Dysfunction and Suprachiasmatic Nucleus-Mediated Circadian Disruption in Humans: A Systematic Review.
Dhinesh M, Bui BV, Sherigar SS et al.
Exp Eye Res·2026·Human·PubMed →
Circadian-based individualised protection against inflammation-cancer transition in atrophic gastritis patients.
Shan C, Guo M, Feng F et al.
EPMA J·2026·Human·PubMed →
Association of tirzepatide with changes in OSA-related measures based on baseline characteristics - post hoc analyses of SURMOUNT-OSA.
Falcon B, Xie CC, Redline S et al.
J Clin Sleep Med·2026·Human·Sleep Apnea, Weight Loss·PubMed →
FBXL21 regulates diurnal proteostasis in skeletal muscle by targeting DNAJB6 and client proteins.
Lim JY, Wi J, Wirianto M et al.
EMBO Rep·2026·Animal·PubMed →
Circadian control of dopaminergic signaling to the mushroom body regulates sleep through rhythmic Pka-C1 transcription in Drosophila.
Lago Solis B, Koch R, Nagoshi E
Curr Biol·2026·Animal·PubMed →
Photoperiod driven modulation of behavior, gut microbiota, and brain transcriptomics in zebrafish.
Sivarajan D, Pothayi V, Devasia SC et al.
Pflugers Arch·2026·Animal·PubMed →
Influence of Intravenous Norepinephrine Administration on Melatonin Plasma Concentration in Awake and Anaesthetised Healthy Adult Volunteers.
Sahinovic MM, de Keijzer IN, Stern M et al.
J Pineal Res·2026·Animal·PubMed →
Sleep and circadian rhythm characteristics in unaffected first-degree relatives of individuals with schizophrenia and bipolar disorder.
Kurtulmus A, Parlakkaya Yildiz FB, Eregli B et al.
Sleep Biol Rhythms·2026·Animal·PubMed →
GA Eases Atherosclerosis by Regulating Circadian Rhythm.
Hao C, Ren F, Guo Y et al.
Pharmazie·2026·Animal·Cardiovascular Risk·PubMed →
Paraventricular Hypothalamic GLP-1R Neurons Mediate Propofol-Induced Suppression of Food Intake.
Liang J, Yin M, Su Y et al.
J Integr Neurosci·2026·Animal·Neuroprotection·PubMed →
Sympathetic activation links light exposure and rest-activity rhythm to liver injury and bile acid dysregulation.
Yan M, Li JW, Yuan JH et al.
NPJ Biol Timing Sleep·2026·Animal·PubMed →
Monosynaptic GABAergic projections from a subset of suprachiasmatic nucleus neuromedin S neurons suppress preoptic area kisspeptin neuron firing in female mice.
Abdulmajeed WI, Neuman PN, Jamieson BB et al.
J Neurosci·2026·Animal·PubMed →
Chemical regulation of circadian rhythms through inhibition of casein kinase Iδ and α.
Toda T, Senthilvadivel V, Nagai Y et al.
Biochem Biophys Res Commun·2026·Animal·PubMed →
Light-induced remodeling of the Drosophila phosphoproteome regulates visual adaptation through the Trp channel.
Kramer LD, Brandwine-Shemmer T, Pierce LR et al.
Sci Signal·2026·Animal·PubMed →
FKBP5 methylation, temperament, and chronotype in adolescent posttraumatic stress disorder: a preliminary case-control study.
Özaydın Y, Özgür BG, Özaydın BC et al.
Eur J Psychotraumatol·2026·Animal·PubMed →
Cannabidiol (CBD) differentially shapes systemic cytokines and transcriptomic profiles in the liver and spleen: insights from a male mouse model.
Żurowski J, Ocłoń E, Jasielczuk I et al.
Mol Genet Genomics·2026·Animal·Liver Protection, Anti-Inflammatory·PubMed →
CircadiOmics: bioinformatics platform for circadian rhythms.
Changizi Ashtiani K, Baldi P
Bioinformatics·2026·Animal·PubMed →
Behavioural thermoregulation modulates circadian clock gene expression in juvenile Atlantic salmon (Salmo salar).
Alborja-Valado M, López-Patiño M, Oppedal F et al.
J Therm Biol·2026·Animal·PubMed →
Hypothalamic subfield volumes and morphometric covariance network organization in restless legs syndrome.
Kim KT, Lee DA, Yang TW et al.
Sleep Med·2026·Animal·PubMed →
ET B receptors contribute to synchrony between blood pressure and other peripheral circadian rhythms in the Sprague-Dawley rat.
Venegas M, Aponso HM, Pollock DM
Can J Physiol Pharmacol·2026·Animal·PubMed →
Geomagnetic intensity variation and deprivation elicit distinct transcriptomic responses in a migratory insect.
Xie W, Wang Y, Zou L et al.
Insect Mol Biol·2026·Animal·PubMed →
The miR167-ARF8 Module Integrates HSFA1-HSFA2 and RVE4/8-ERF53/54 Transcriptional Cascades to Enhance Plant Thermotolerance.
Li J, Li Y, Chen C et al.
Plant Cell·2026·Animal·PubMed →
Constitutive AtRD29A expression reveals divergent BpCBF3 regulatory mechanisms in birch.
Ge M, Wang X, Hou L et al.
Plant J·2026·Animal·PubMed →
Dynamic Atlas and Energy Metabolism Adaptation of the Liver Proteome During a 24 h Cycle in Vespertilio sinensis.
Wang T, Chu Y, Li X et al.
Biomolecules·2026·Animal·Liver Protection·PubMed →
Clock-Related Genes Mark a Developmental Cortical Maturation Program Associated with Stage-Resolved Responses to Prenatal Immune Activation.
Wang Y, Li S, Jin X
Genes (Basel)·2026·Animal·PubMed →
Genome-Wide Identification of the APRR2 Gene Family and Rind Color Trait Analysis in Zucchini (Cucurbita pepo).
Liu T, Li S, Wu K et al.
Genes (Basel)·2026·Animal·PubMed →
Temporal Variation and Region- and Sex-Specific Expression of GABA(A) Receptor Subunits in the Mouse Suprachiasmatic Nucleus.
Chong J, Cheeseman JF, Pawley MDM et al.
Biology (Basel)·2026·Animal·PubMed →
Hesperetin Attenuates Experimentally Induced Skeletal Muscle Dysfunction by Modulating Time-of-Day-Dependent Gene Expression and Mitochondrial Redox-Related Markers.
Lee S, Sim Y, Lee M et al.
Antioxidants (Basel)·2026·Animal·PubMed →
The Timeless (Tim) Gene Participates in Circadian Rhythm Regulation of the Ridgetail White Prawn, Exopalaemon carinicauda.
Tian C, Zhu J, Chen X et al.
Animals (Basel)·2026·Animal·PubMed →
Dysregulation of circadian clock gene BMAL1 and cell cycle regulator WEE1 in pediatric AML.
Oraei Sajjadi K, Ayatollahi H, Sheikhi M et al.
Mol Biol Rep·2026·Animal·PubMed →
Circadian Norepinephrine Rhythm Regulates Outflow Facility and IOP in Rat Eyes.
Zamitalo-Pomares A, Khareedu K, Passaglia CL
Invest Ophthalmol Vis Sci·2026·Animal·PubMed →
Trimester-specific associations of methyl-donor nutrients and prenatal dietary patterns with adolescent blood leukocyte circadian gene DNA methylation.
Lee JT, Goodrich JM, Dolinoy DC et al.
J Dev Orig Health Dis·2026·Animal·PubMed →
Biotechnological adaptation of high-yielding, gibberellin-overproducing Populus trees to seasonal growth patterns.
Jurca M, Sjölander J, Mariën B et al.
J Exp Bot·2026·Animal·PubMed →
The circadian clock component OsRVE6a orchestrates daytime SA-JA signaling crosstalk to enhance rice defenses.
Li J, Li TY, Zhuang Y et al.
Plant Commun·2026·Animal·PubMed →
Per2 contributes to chronic noise-induced hepatic lipogenesis associated with PPARγ/SREBP-1 signaling.
Wang C, Zhang X, Wang T et al.
Ecotoxicol Environ Saf·2026·Animal·PubMed →
Diurnal Insulin Clearance and Circadian Metabolic Gene Signatures in MASLD: Integrative Multi-Dataset Physiological and Transcriptomic Analysis.
Guo L, Yin Y, Sun Y et al.
Metabolites·2026·Animal·PubMed →
Integrated respirometry and metabolomics unveil circadian metabolic dynamics in Drosophila.
Akhtar F, Malik DM, Sengupta A et al.
Elife·2026·Animal·PubMed →
Multigenerational daytime-restricted feeding exacerbates irradiation-induced hepatic DNA damage and aging in mice.
Sun L, Huang K, Cheng H et al.
Front Nutr·2026·Animal·PubMed →
SETDB1 cooperates with the CRL4B complex to promote colorectal cancer tumorigenesis by disrupting circadian rhythm.
Zhang M, Yan D, Zhang J et al.
Oncogene·2026·Animal·PubMed →
Phosphorylation destabilizes Per3 to promote gallbladder carcinoma.
Fan K, Cheng X, Wang C et al.
Exp Cell Res·2026·Animal·PubMed →
Phase response curve and RNA-sequencing demonstrate spiders' sensitivity to light and pinpoint candidate light-responsive genes.
Toporikova N, Cheng W, Qian L et al.
PLoS One·2026·Animal·PubMed →
Association of Circadian Syndrome with Incident Risk of 23 Site-Specific Cancers: A Large-Scale Prospective Study in the UK Biobank.
Wang J, Jiang F, Wu R et al.
Research (Wash D C)·2026·Animal·PubMed →
Melatonin receptor 1 signaling modulates the metabolic response to high-fat diet in female melatonin-proficient mice.
Goyal V, Tosini G
Front Endocrinol (Lausanne)·2026·Animal·Liver Protection, Glycemic Control·PubMed →
CCRG1 Bridges Circadian Clock Regulation to Plant Developmental Transitions via Ubiquitin-Mediated Control.
Chu R, Wang J, Wei Z
Plant Cell Environ·2026·Animal·PubMed →
Hypoxia up-regulated 1 (HYOU1) is involved in hepatic steatosis via N6-methyladenosine (m(6)A)-dependent stabilization and modulation of circadian clock genes.
Huang Z, Chen C, Li Y et al.
Biochim Biophys Acta Gen Subj·2026·Animal·PubMed →