Research Index

Palmitoyl Tripeptide-5 Research Index

PSI surfaces 50 peer-reviewed studies on Palmitoyl Tripeptide-5, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.

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50 studies

[Bladder Pain Syndrome Associated with Detrusor Underactivity and Bladder Outlet Obstruction : A Case Report].

Kozen N, Kyoda Y, Hashimoto K et al.

Hinyokika Kiyo·2026·Human·PubMed →

Retrospective study of visual acuity changes in patients with interstitial cystitis receiving pentosan polysulfate sodium.

Yuan Z, Vaughan S, Jeffcoat C et al.

Curr Med Res Opin·2026·Human·PubMed →

A Novel Three-Dimension Printed Individualized Curved-Needle-Based Interstitial Brachytherapy for Re-Irradiation in Uterine Fundus-Involving Recurrent Cervical Cancer: A Case Report.

Zhang Y, Zhang J, Zhong M et al.

Curr Oncol·2026·Human·PubMed →

External validation of combining clinical parameters and urinary biomarker clusters and development of a nomogram for identifying bladder-centric interstitial cystitis/bladder pain syndrome in patients with lower urinary tract symptoms.

Tian JH, Yu WR, Jhang JF et al.

Int Urol Nephrol·2026·Human·PubMed →

Impact of a Patient-Centered Chronic Pelvic Pain Toolkit on Patient Satisfaction: A Randomized Control Pilot Study.

Cosgriff L, Glowacki K, Morozov V et al.

J Minim Invasive Gynecol·2026·Human·PubMed →

Functional bladder capacity can reflect the bladder condition and treatment outcome in patients with interstitial cystitis/bladder pain syndrome.

Yu WR, Kuo HC

World J Urol·2026·Human·PubMed →

Severe bilateral retinal degeneration following a twenty-six-year pentosan polysulfate sodium exposure: a case report.

Zhao AT, Wibbelsman TD, Calotti M et al.

Am J Ophthalmol Case Rep·2026·Human·PubMed →

Therapeutic efficacy of multimodal therapy for patients with interstitial cystitis/bladder pain syndrome refractory to previous bladder monotherapy.

Yu WR, Jhang JF, Jiang YH et al.

Int Urol Nephrol·2026·Human·PubMed →

Bladder tumors in patients initially diagnosed with interstitial cystitis: a ten-year retrospective study.

Deng S, Jiang R, Wu S et al.

Int Urol Nephrol·2026·Human·PubMed →

Role of psychosocial factors of symptom flares in a cohort of patients with urologic chronic pelvic pain syndrome: A cognitive-affective approach.

Lackner JM, Xiong Y, Rogers AH et al.

Behav Res Ther·2026·Human·PubMed →

Editorial Comment on Long-Term Clinical Outcome of Transurethral Resection of Hunner Lesions Combined With Bladder Hydrodistention for Patients With Interstitial Cystitis at a Tertiary Center in Japan.

Kuo HC

Int J Urol·2026·Human·PubMed →

Imaging Mass Cytometry Immune Profiling of Hunner Lesions in a Convenience Sample of Patients With Interstitial Cystitis/Bladder Pain Syndrome.

Cotechini T, Kim N, Hindmarch CCT et al.

J Urol·2026·Human·PubMed →

Efficacy and Safety of Dupilumab in Adults with Prurigo Nodularis with or Without Atopic Comorbidities: A Subgroup Analysis from Two Randomized Phase III Clinical Trials.

Kim BS, Gonçalo M, Ugajin T et al.

Am J Clin Dermatol·2026·Human·PubMed →

Validation of the Italian Version of the O'Leary-Sant Questionnaire for Patients with Bladder Pain Syndrome/Interstitial Cystitis.

Natale F, Campagna G, Caramazza D et al.

Int Urogynecol J·2026·Human·PubMed →

Efficacy and Safety of Submucosal Intravesical Injection of Platelet-Rich Plasma in the Treatment of Interstitial Cystitis/Painful Bladder Syndrome.

Mourad MS, Tawfick A, Kotb M et al.

Int Urogynecol J·2026·Human·PubMed →

Pigmentary Maculopathy in Patients with Interstitial Cystitis: Association with Pentosan Polysulfate and Other Therapies.

Qin S, Evans JK, Jeong C et al.

Ophthalmol Sci·2026·Human·PubMed →

Application study of pressure- and volume-controllable balloon in direct visualisation interstitial cystitis dilation surgery.

Wei W, Gao C, Wang H et al.

Int Urol Nephrol·2026·Human·PubMed →

Interstitial Cystitis/Bladder Pain Syndrome: Why a Global Patient Registry Is Critically Needed.

Mezes C, Niimi A, Kasyan G et al.

Neurourol Urodyn·2026·Human·PubMed →

Interstitial Cystitis/Bladder Pain Syndrome Patient Phenotyping.

Wolff DT, Tranchina S, Schrepf A et al.

Neurourol Urodyn·2026·Human·PubMed →

Role of Bruton's Tyrosine Kinase in mast cell driven urothelial barrier injury in an LL-37 induced model of interstitial cystitis.

Wang G, Li BS, Chu JY et al.

Sci Rep·2026·Animal·PubMed →

Social Media as a Source of Information on Interstitial Cystitis/Bladder Pain Syndrome: Support Tool or Misinformation?

Gubbiotti M, Gilli C, Pelizzari L et al.

Neurourol Urodyn·2026·Animal·PubMed →

Evaluation of an oral Beta-caryophyllene Indena Phytosome(®) for the treatment of pain and inflammation in interstitial cystitis.

White H, Dickson K, Scott C et al.

Clin Hemorheol Microcirc·2026·Animal·PubMed →

MMP9 in macrophages: A pivotal biomarker associated with immune dysregulation in interstitial cystitis/bladder pain syndrome.

Dong X, Guo Z, Chen X et al.

Urologia·2026·Animal·PubMed →

Triamcinolone acetonide nanoparticles ameliorate interstitial cystitis and anxiety/depression by targeting the bladder-metabolic-brain axis.

Liu Z, Ju Q, Yang Y et al.

Mater Today Bio·2026·Animal·PubMed →

IVF in endometriosis: emerging evidence of exacerbation of pelvic pain and potential predictors.

Vibert J, Maalouf E, Wenger JM et al.

Hum Reprod Open·2026·Animal·PubMed →

Hyaluronic Acid Increase Anti-Inflammatory and Regenerative Effects of Adipose-Derived Mesenchymal Stem Cells in an Interstitial Cystitis Rat Model.

Dawood AF, Othman RQA, Albow BM et al.

Appl Biochem Biotechnol·2026·Animal·PubMed →

Normalization of magnesium deficiency with magnesium-L-Threonate alleviates bladder overactivity in cyclophosphamide-induced cystitis: Mechanisms of inflammatory modulation and barrier restoration.

Chen J, Luo R, Huang J et al.

Eur J Pharmacol·2026·Animal·PubMed →

Retinal Pigment Epithelium Injury in Pentosan Polysulfate Exposure: Morphologic Changes, Phagocytic Deficits, and Mitochondrial Dysfunction.

Rajagopalan A, Satyanarayana G, Kumpakha R et al.

bioRxiv·2026·Animal·PubMed →

Association Between Depression Subtypes and Interstitial Cystitis/Bladder Pain Syndrome.

Chang KM, Lee MH, Chen YF et al.

Int Urogynecol J·2026·Animal·PubMed →

ROS-responsive nanodiscs for STING-NF-κB pathway inhibition and glycosaminoglycan layer restoration in interstitial cystitis/bladder pain syndrome therapy.

Zhang P, Tan R, Huang C et al.

J Control Release·2026·Animal·PubMed →

Late Development of Clinically Apparent Pentosan Polysulfate Maculopathy after Drug Cessation.

N'jai B, Rajagopalan A, Milner D et al.

Retin Cases Brief Rep·2026·Animal·PubMed →

Effectiveness of CO(2) micro-ablative vaginal laser therapy in the treatment of recurrent cystitis.

Filippini M, Sozzi J

Arch Ital Urol Androl·2026·Animal·PubMed →

Case Report: Neuropsychiatric improvement after treatment of pelvic venous disorder in a multisyndromic patient.

Smith SJ, Sichlau MJ, Rowe PC et al.

Front Cardiovasc Med·2025·Human·PubMed →

Efficacy and safety of pentosan polysulfate therapy in patients with interstitial cystitis for relief of lower urinary tract symptoms: 15-year single center experience.

Song SH, Song B, Jung G et al.

Prostate Int·2025·Human·PubMed →

Successful treatment of chronic spontaneous urticaria and bladder pain syndrome with montelukast and/or omalizumab: a case report.

Bulut G

J Med Case Rep·2025·Human·PubMed →

Association of specific HLA alleles in patients with interstitial cystitis suggesting autoimmunity.

Tabansky Stern I, Wang J, Moldwin RM et al.

Front Mol Med·2025·Human·PubMed →

Low-energy extracorporeal shock-wave therapy with or without intravesical botulinum toxin A instillations for refractory interstitial cystitis/bladder pain syndrome: a randomized double-blind trial of clinical and biomarker outcomes.

Jhang JF, Kuo HC

Int Urol Nephrol·2025·Human·PubMed →

Discrete mathematical network analysis bridging clinical vocabulary and patient discourse in interstitial cystitis/bladder pain syndrome online communications.

Okui N, Ichino K, Sakuma Y et al.

Sci Rep·2025·Human·PubMed →

Effects of intravesical cocktail instillation on outcomes and serum pain factors of patients with bladder pain syndrome.

Jia Y, Zhang Y, Wang B et al.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub·2025·Human·PubMed →

The role of clinical nurse specialists in the management of patients with bladder pain syndrome.

Hillery S

Br J Nurs·2025·Human·PubMed →

Quality of patient information on interstitial cystitis from artificial intelligence chatbots.

Santucci J, Stapleton P, Ibrahim J et al.

BJU Int·2025·Human·PubMed →

Treatment Outcomes of Patients With Hunner Interstitial Cystitis Who Received Augmentation Enterocystoplasty or Bladder-Preserving Therapy.

Lee YS, Chang TL, Chen SF et al.

Int Neurourol J·2025·Human·PubMed →

Long-Term Clinical Outcomes of Transurethral Resection of Hunner Lesions Combined With Bladder Hydrodistension for Patients With Interstitial Cystitis at a Tertiary Referral Center in Japan.

Akiyama Y, Hashimoto K, Niimi A et al.

Int J Urol·2025·Human·PubMed →

Systemic ozone therapy improves the quality of life in patients with bladder pain syndrome.

Martinelli M, Glielmo A, Licci MR et al.

Bladder (San Franc)·2025·Human·PubMed →

Metachronous Bilateral Nephrectomy, Supratrigonal Cystectomy, and Living Donor Renal Transplantation in a Patient With Chronic Kidney Disease due to Interstitial Cystitis and Total Urethral Stricture.

Sholan R, Aliyev R, Almazkhanli A et al.

Case Rep Med·2025·Human·PubMed →

Long-term functional outcomes and complications of robot-assisted laparoscopic supratrigonal cystectomy with augmentation cystoplasty in adult patients with neurogenic lower urinary tract dysfunction and interstitial cystitis/bladder pain syndrome: A single-centre experience.

Batard T, Mesnard B, Levesque A et al.

BJUI Compass·2025·Human·PubMed →

Navigating the decision landscape: understanding interstitial cystitis/bladder pain syndrome patients' motivations and medical support needs for fecal microbiota transplantation: a qualitative research.

Liu H, Wei Y, Jiang P et al.

BMC Complement Med Ther·2025·Human·PubMed →

Camrelizumab plus SOX chemotherapy as adjuvant therapy for pathological stage III gastric or gastroesophageal junction adenocarcinoma: a prospective, multicenter, single-arm, phase II trial.

Jin H, Yu J, Gao Y et al.

Ther Adv Med Oncol·2025·Human·PubMed →

Association of HRQOL With Symptom Patterns in an Online Cohort of Patients With Interstitial Cystitis/Bladder Pain Syndrome.

Galvez A, Kuhlmann P, Barker M et al.

Urology·2025·Human·PubMed →

Patient Related Outcomes for Interstitial Cystitis/Bladder Pain Syndrome Recommendations for Clinical Trials and General Urology Practice.

Hayes B, Namugosa M, Evans RJ et al.

Neurourol Urodyn·2025·Human·PubMed →