Research Index

Thymosin Beta-4 Research Index

PSI surfaces 50 peer-reviewed studies on Thymosin Beta-4, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.

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50 studies

Muscle growth mediates the increases in muscle strength in untrained older women.

Kassiano W, Stavinski N, Costa B et al.

Appl Physiol Nutr Metab·2026·Human·Muscle Recovery·PubMed →

Does longer-muscle length resistance training cause greater longitudinal growth in humans? A systematic review.

Wolf M, Korakakis PA, Roberts MD et al.

Sports Med Health Sci·2026·Human·PubMed →

Concurrent training with long-interval HIIT does not impair skeletal muscle protein synthesis or hypertrophy: little evidence of an "interference effect".

Conceição M, Vechin FC, Telles G et al.

J Appl Physiol (1985)·2026·Human·Muscle Recovery·PubMed →

A systematic review and meta-analysis examining if hyperplasia occurs in humans in response to resistance exercise.

Barton NV, Gowda HN, Dankel SJ

J Sports Med Phys Fitness·2026·Human·Muscle Recovery·PubMed →

Mechanical Overload-Induced Retinoid Metabolism Is Involved in Protein Synthesis in Skeletal Muscle of Female Mice.

Kitakaze T, Nakatsuji A, Harada N et al.

J Nutr Sci Vitaminol (Tokyo)·2026·Animal·Muscle Recovery·PubMed →

A skeletal muscle atlas shows neuromuscular junction adaptations to growth and atrophy.

Campanario S, Grima-Terrén M, Rommelfanger M et al.

Dev Cell·2026·Animal·PubMed →

mTORC1 and nuclear ERK spatially control translation in cardiomyocytes through 4EBP1 phosphorylation.

Uchida K, Scarborough EA, Pruzinsky E et al.

Sci Signal·2026·Animal·PubMed →

Does Performing Partial Repetitions Beyond Momentary Failure Enhance Muscle Hypertrophy in Volume-Load-Equated Calf-Raise Resistance Training?

Goli A, Attarieh P, Nunes JP et al.

Int J Exerc Sci·2026·Animal·PubMed →

Overactive PDGFRα and PDGFRβ promote distinct phenotypes of skeletal muscle fibrosis and stiffness, with PDGFRβ also driving muscle growth.

Gimla M, Olszewski S, Brown JL et al.

Am J Physiol Cell Physiol·2026·Animal·PubMed →

Targeting C/EBPβ to Suppress Myocardial Fibrosis in Hypertensive Heart Disease: Role of the ACE2/Ang-(1-7) Pathway.

Tie Y, Lin Z, Zhang M et al.

J Cell Mol Med·2026·Animal·Tissue Remodeling, Cardiovascular Risk·PubMed →

Caffeic acid phenethyl ester ameliorates high-fat diet-induced muscle textural deterioration in grass carp (Ctenopharyngodon idellus) by modulating adipose-muscle crosstalk via myostatin-taz signaling.

Li H, Tian Z, Wei M et al.

Anim Nutr·2026·Animal·PubMed →

Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis.

Wang Y, Xu L, Pan C et al.

Adv Sci (Weinh)·2026·Animal·PubMed →

Left Ventricular and Right Ventricular Hypertrophy Modelling to Study PAPP-A-Mediated IGFBP-4 Cleavage-a Mechanism That Regulates IGF Bioavailability in Adult Rats.

Artemieva MM, Makeeva AV, Adasheva DA et al.

Int J Mol Sci·2026·Animal·GH Activity·PubMed →

Active immunization against myostatin and activin A improves skeletal muscle performance in growth hormone-deficient mice.

Mansoor MAM, Ashiqueali SA, Alam MT et al.

Geroscience·2026·Animal·PubMed →

THBS4 Regulates Pulmonary Hypertension via TGF-β/SMAD2 Signaling.

Zeng J, Li D, Wang J et al.

Hypertension·2026·Animal·PubMed →

Optimizing Strength and Hypertrophy: The Combined Effect of Intensity and Velocity Loss Thresholds in Bench Press Training.

Pareja-Blanco F, Sánchez-Valdepeñas J, Cornejo-Daza PJ et al.

Med Sci Sports Exerc·2026·Animal·PubMed →

[The mechanism of Rap1GAP in ventricular hypertrophy and interstitial fibrosis induced by angiotensin Ⅱ].

Li XY, Shan TT, Yao Y et al.

Zhonghua Xin Xue Guan Bing Za Zhi·2026·Animal·PubMed →

Chondrocyte proliferation without inflammation underlies botulinum toxin-induced mandibular enthesis bone hypertrophy in rats.

Mermet M, Massiquot Q, Gaborit N et al.

Biochem Biophys Res Commun·2026·Animal·Anti-Inflammatory·PubMed →

Hamstrings-to-quadriceps ratio in female and male children and adolescents across the velocity spectrum.

Searles SA, Shoemaker ME, Cramer JT et al.

Eur J Appl Physiol·2026·Animal·PubMed →

Developmental expression patterns of the FXR-IGF axis during early skeletal muscle growth in ducks.

Chen L, Wang X, Luo J et al.

Poult Sci·2026·Animal·PubMed →

Growth performance and muscle histological characteristics of IPB-D3 chickens reared under intensive and free-range systems.

Prawira AY, Yuneldi RF, Khaerunnisa I et al.

Vet World·2026·Animal·PubMed →

Smooth muscle NR4A3 upregulation caused by endothelial Caveolin-1 deficiency mediates vascular remodeling and pulmonary hypertension.

Huang J, Liu J, Guo Y et al.

Free Radic Biol Med·2026·Animal·PubMed →

AJUBA Attenuates Pathological Cardiac Hypertrophy by Enhancing NEDD4-Mediated Ubiquitination and Degradation of DVL2.

Zhuang L, Xiong J, Zhou W et al.

Cell Biol Int·2026·Animal·PubMed →

High-dose ginsenoside Rg5 induces tissue-specific metabolic and transcriptional responses in muscle and liver of grass carp (Ctenopharyngodon idella).

Ren L, Han X, Wang Q et al.

Comp Biochem Physiol Part D Genomics Proteomics·2026·Animal·PubMed →

The therapeutic potential of Myoki, a novel peptide in muscle atrophy: mechanisms and applications.

Kim EM, Kim SS, Hyun YG et al.

Front Pharmacol·2026·Animal·PubMed →

Macrodystrophia Lipomatosa: A Rare Case of Right Lower Extremity Gigantism Associated With Syndactyly.

Shehzadi HS, Atif S, Dogar IH et al.

Clin Case Rep·2026·Animal·PubMed →

CELF1 Downregulation Promotes Cardiomyocyte Hypertrophy via Regulating Alternative Splicing of Tead1.

Hu L, Zhu K, Zeng S et al.

Genes (Basel)·2026·Animal·PubMed →

Dysregulated Klotho and FGF23 signalling aggravates vascular remodelling in age-related pulmonary hypertension.

Perret PL, Kim JH, Winkler A et al.

Cardiovasc Res·2026·Animal·PubMed →

Targeting Heightened Inflammatory Tone in IUGR Neonatal Lambs via Daily Oral Supplementation of ω-3 PUFA Improved Growth Rates, Muscle Mass, and Adiponectin Signaling.

White MR, Gibbs RL, Grijalva PC et al.

Metabolites·2026·Animal·PubMed →

Progressive Overload Affects the Magnitude of Muscle Hypertrophy.

Kassiano W, Santos-Melo V, Manske I et al.

Med Sci Sports Exerc·2026·Animal·PubMed →

Runx2 Regulated Airway Homeostasis Is Disrupted in Asthma.

Wang J, Faiz A, Ge Q et al.

FASEB J·2026·Animal·PubMed →

Dynamic transcriptome analysis highlights collagen-integrin-mediated extracellular matrix remodeling underlying sexual dimorphism in the amplexus muscle of Bufo gargarizans.

Mi Z, Liu X, Liu Y et al.

Biol Sex Differ·2026·Animal·Tissue Remodeling, Muscle Recovery·PubMed →

Stage-specific transcriptional atlas of goose satellite cells uncovers molecular dynamics driving embryonic skeletal muscle development.

Wang C, Yang Y, Liu Y et al.

Poult Sci·2026·Animal·Muscle Recovery·PubMed →

Overexpression of Rtl1 via synonymous mutation silencing miRNA target site drives skeletal muscle hypertrophy and inflammation in mice.

Song X, Niu L, Fan X et al.

BMC Biol·2026·Animal·Muscle Recovery, Anti-Inflammatory·PubMed →

Paeonol alleviates pulmonary arterial hypertension by activation of BRCC3.

Yin Q, Xiong Z, Wang X et al.

Phytomedicine·2026·Animal·PubMed →

Echinatin Alleviates Experimental Pulmonary Hypertension by PPARγ Pathway Activation.

Feng W, Bai D, Mo S et al.

FASEB J·2026·Animal·PubMed →

Hypertrophic Effects of Single- versus Multi-Joint Exercise: A Direct Comparison Between Knee Extension and Leg Press.

Kinoshita M, Maeo S, Kobayashi Y et al.

Med Sci Sports Exerc·2026·Animal·PubMed →

Exercise intensity-dependent cardiac telocyte expansion is associated with physiological growth despite JAK/STAT pathway inactivity in male Wistar rats.

Borjian Fard M, Choobineh S, Soori R et al.

Exp Physiol·2026·Animal·Anti-Inflammatory·PubMed →

The calcimimetic etelcalcetide attenuates pressure overload-induced cardiac hypertrophy in rats with and without chronic kidney disease.

Okamoto H, Goto S, Nose Y et al.

Biomed Pharmacother·2026·Animal·PubMed →

Genetic Determinants of Heart Failure Susceptibility and Response in the Collaborative Cross Mouse Population.

Kimball TH, Luu AN, Gural B et al.

Genetics·2026·Animal·PubMed →

Swimming is superior to running in inducing physiological cardiac hypertrophy and enhancing myocardial performance.

Yoshizaki A, Antonio EL, Santos LD et al.

Sci Rep·2026·Animal·PubMed →

Regulation of skeletal muscle development and metabolism in broiler chickens by Urolithin A through threonine kinase 1 pathway activation.

Wu L, Peng L, Zhao X

Poult Sci·2026·Animal·Muscle Recovery·PubMed →

Phosphatidylinositol 4-Kinase IIIβ: A Therapeutic Target for Contractile Dysfunction in Hypertrophic Cardiomyocytes.

Willemars MMA, Sun A, Wang S et al.

Int J Mol Sci·2026·Animal·PubMed →

Porcine FRZB (sFRP3) Negatively Regulates Myogenesis via the Wnt Signaling Pathway.

Nie J, Fu Y, Hao X et al.

Animals (Basel)·2026·Animal·PubMed →

Fibre Type-Specific Proteomics Reveals Shared and Distinct Skeletal Muscle Adaptations to Resistance Training and Beta(2)-Adrenergic Agonist.

Jessen S, Di Credico A, Moreno-Justicia R et al.

J Cachexia Sarcopenia Muscle·2026·Animal·Muscle Recovery·PubMed →

Dual-Mode Ventilation Promotes Diaphragm Function Recovery in Rats With Ventilator-Induced Diaphragmatic Dysfunction by Upregulating Insulin-Like Growth Factor-1.

Zheng XZ, Wu L, Chen Q et al.

J Surg Res·2026·Animal·GH Activity·PubMed →

Resistin-Like Molecule Beta Participates in Calcium Regulation Via Direct Interaction With CaSR and a PLC-IP(3)R-Dependent Mechanism in Hypoxia-Induced Pulmonary Hypertension.

Liu G, Tian H, Tan J et al.

Pulm Circ·2026·Animal·PubMed →

Signal Recognition Granule Receptor Beta Subunit Promotes Arrhythmogenic Remodeling in the Heart Failure Mice.

Zhang J, Pan Y, Gong Y et al.

J Am Heart Assoc·2026·Animal·Tissue Remodeling·PubMed →

METTL14-mediated RNA m(6)A modifications of TET1 and TET2 in duck myoblast differentiation.

Liu J, Wu J, Liao Z et al.

Poult Sci·2026·Animal·Muscle Recovery·PubMed →

Histopathology and spatial transcriptomics jointly map myofiber-specific pathological programs in mTORC1-driven myopathy.

Hsu JE, Zhao Q, Cheng W et al.

bioRxiv·2025·Animal·PubMed →