Research Index
Tesofensine Research Index
PSI surfaces 50 peer-reviewed studies on Tesofensine, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
50 studies
Global, regional, and national burden of exposure to chewing tobacco, 1990-2023: a systematic analysis of the Global Burden of Disease Study 2023.
GBD 2023 Chewing Tobacco Collaborators
Lancet Glob Health·2027·Animal·PubMed →
Effects of age on association between obstructive sleep apnea and metabolic syndrome in the Japanese patient population.
Kataoka K, Dohi T, Kasai T et al.
Sleep Biol Rhythms·2026·Human·PubMed →
Drug-Induced Orthostatic Hypotension in UK Primary Care: A Self-Controlled Case Series Study.
Bhanu C, Petersen I, Orlu M et al.
Clin Epidemiol·2026·Human·PubMed →
Development and Validation of Daping Orthopedics Operative Risk Scoring System for Geriatric Hip Fracture (DOORS-GHF) for Predicting Postoperative Outcomes in Geriatric Hip Fracture Patients: A Multicenter Retrospective Comparative Study.
Gong Z, Wang Y, Zhu W et al.
Orthop Surg·2026·Human·PubMed →
Healthcare Professionals' Perceptions of the Division of Responsibilities Between Primary and Outpatient Specialist Care in Chronic Respiratory Disease Management: A Cross-Sectional Survey in 10 European Countries.
Mularczyk-Tomczewska P, Jankowski M, Nurmi H et al.
Med Sci Monit·2026·Human·PubMed →
Study on blueberries, protein and exercise for improving frailty and cardiovascular disease (STRONG): protocol for a parallel-group randomised controlled superiority trial in older Nova Scotians.
Cahill LE, Grandy SA, Gottheil C et al.
BMJ Open·2026·Human·Cardiovascular Risk·PubMed →
Angiography-derived index of microcirculatory resistance in older patients with acute coronary syndrome undergoing percutaneous coronary intervention.
Magistri M, Collet C, Ribichini FL et al.
Int J Cardiol·2026·Human·PubMed →
Impact of a Short-term Yoga Lifestyle Programme on Circulating Serum Klotho Levels in Patients with Type 2 Diabetes: An Exploratory Study.
Snigdha A, Majumdar V, Ramegowda KS
Indian J Endocrinol Metab·2026·Human·PubMed →
Prognostic value of hemoglobin-to-serum creatinine ratio in patients with coronary artery disease and reduced kidney function following percutaneous coronary intervention.
Fang S, Liu H, Wang Y et al.
Front Cardiovasc Med·2026·Human·PubMed →
Mid-term effects of a parenting programme on early childhood development and maternal health in Vietnam: protocol for a follow-up of a cluster-randomised controlled trial.
Baek Y, Tran T, Davison N et al.
BMJ Open·2026·Human·PubMed →
Lebrikizumab in Atopic Dermatitis: Associations of Patient Characteristics and Treatment History with Clinical Outcomes.
Gori N, Galluzzo M, Ippoliti E et al.
Dermatitis·2026·Human·PubMed →
Engagement of Social Support Systems in Patients Being Considered for and Following Advanced Heart and Lung Surgical Therapies: An ISHLT Expert Consensus Statement.
McIlvennan CK, Anthony SJ, Dobbels F et al.
J Heart Lung Transplant·2026·Human·PubMed →
Impact of Premorbid Function and Comorbidities in Geriatric Traumatic Brain Injury Patients: A Systematic Review.
Badero OJ, Bakare S, Moosa MY et al.
Cureus·2026·Human·PubMed →
Primary Thromboprophylaxis in Patients with Malignancy and Central Venous Catheters: TRIM-Line Randomized Controlled Trial-Design and Rationale.
Wang TF, Ikesaka R, Mahé I et al.
Thromb Haemost·2026·Human·PubMed →
Physiotherapy implementation and hospitalisation-associated disability according to prehospital functional status in older patients with heart failure: a secondary analysis of a prospective nationwide multicentre registry.
Hamazaki N, Kato M, Iida Y et al.
Age Ageing·2026·Human·PubMed →
Herpes Zoster in Aging Patients: Risk Factors and Prevention Strategies.
Okoye C, Ashby B, Campos R et al.
Int J Gen Med·2026·Human·PubMed →
Physical exercise and circulating α-Klotho in humans: a systematic review and meta-analysis with emphasis on older adults.
Abduldayeva AA, Iskakova SA, Doszhanova GN et al.
Front Sports Act Living·2026·Human·PubMed →
Young Mice Exhibit Increased Relative Ventricular Remodeling After AMI-A Longitudinal CMR Study.
Lemcke H, Wörner P, Dalmer A et al.
Aging Cell·2026·Animal·Longevity·PubMed →
Religious order membership and cognitive function: Evidence for slower late-life decline despite higher incident dementia.
Jiakponnah NN, Biose OD, Sivebukola I et al.
J Alzheimers Dis·2026·Animal·PubMed →
Identification of Endonuclease G binding protein using a method which specifically isolates binding partners within subcellular compartments.
Kang H, Kim EB, Brown AL et al.
Mol Cell Proteomics·2026·Animal·PubMed →
Synergistic Effects of Bisphosphonates and Physical Exercises and Modalities on Osteoporosis Management: A Systematic Review and Meta-Analysis.
Jin J, Ma H
J Aging Phys Act·2026·Animal·PubMed →
Cranial bone marrow-derived monocytes promote neuroinflammation in chronic traumatic brain injury.
Lu Z, Wang C, Gong P et al.
Sci Transl Med·2026·Animal·Neuroprotection, Anti-Inflammatory, Longevity·PubMed →
CCL2 and CXCL2 are markers of delirium vulnerability in community dwelling older people.
Moorey H, Botfield HF, Krogseth M et al.
Age Ageing·2026·Animal·Longevity·PubMed →
Global, Regional, and National Burden of Heart Failure, 1990-2023: A Systematic Analysis for the Global Burden of Disease Study 2023.
GBD 2023 Heart Failure Collaborators, Johnson CO, Abbasi M et al.
JAMA Cardiol·2026·Animal·PubMed →
An Early Value Assessment of Biomarker-Guided Precision Medicine for Treatment-Resistant Hypertension: A Headroom and Threshold Analysis.
Abu-Zahra T, Grimm S, Scholte M et al.
Appl Health Econ Health Policy·2026·Animal·PubMed →
ASO Visual Abstract: Perioperative Outcomes and Pathological Response After Neoadjuvant Nivolumab Plus Platinum Chemotherapy in Clinically Node-Negative Non-Small Cell Lung Cancer.
Watanabe T, Nomura K, Takamori S et al.
Ann Surg Oncol·2026·Animal·PubMed →
The Mediterranean-style Japanese Diet: A Systematic Review of the Recommendations for an Anti-aging Lifestyle.
Santa K, Vitale E, Watanabe K et al.
Endocr Metab Immune Disord Drug Targets·2026·Animal·PubMed →
Frailty Index Progression Around Hypertension Diagnosis in 14 Countries.
Tang D, Goubar A, Pantoja-Ruiz C et al.
Hypertension·2026·Animal·PubMed →
Effects of Concurrent Training plus Cricket Protein Hydrolysate Supplementation on Blood Pressure, Arterial Stiffness, and Heart Rate Variability in Older Adults: A Randomized Controlled Trial.
Vaithanomsat P, Tumnark P, Sukatta U et al.
Ann Geriatr Med Res·2026·Animal·PubMed →
Genetic Insights Into Protective Effects of GLP-1 Receptor Agonists on Stroke and Alzheimer Disease Across Ancestries.
Caro-Châtelier I, Sargurupremraj M, Yang C et al.
Neurol Genet·2026·Animal·PubMed →
Association between physical activity and incident dementia among individuals with hypertension.
Yang C, Zhao Y, Li J et al.
Front Aging Neurosci·2026·Animal·PubMed →
Optimal duration of anticoagulation after successful catheter ablation for atrial fibrillation: insights from recent randomized trials.
Lin M, Rong B, Zhong J et al.
Commun Med (Lond)·2026·Animal·PubMed →
IGF-1/SLC25A33 Maintains Blood-Labyrinth Barrier Integrity by Suppressing TGF-β/Smad2-Mediated Pericyte Activation in Age-Related Hearing Loss.
Xu R, Tang J, Lin H et al.
Aging Cell·2026·Animal·GH Activity, Longevity·PubMed →
Accelerated biological aging in the association between early-life tobacco smoke exposure and dementia risk: An exploratory mediation analysis.
Yu L, Deng H, Yang M et al.
J Alzheimers Dis·2026·Animal·PubMed →
Sex-specific shape models to disentangle sex effects and age-associated anatomical variation in biventricular cardiac anatomy.
Buoso S, Visser VL, Leuders P et al.
Eur Heart J Imaging Methods Pract·2026·Animal·PubMed →
Reducing rural health inequity through drone-based delivery: a spatial multi-criteria decision framework prioritizing epidemiological vulnerability in hub location.
Zhong J, Zhao Y
Front Public Health·2026·Animal·PubMed →
Epidemiology and Quality of Care for Aboriginal and Torres Strait Islander Peoples Treated by Emergency Medical Services for Stroke in Victoria, Australia: Retrospective Analysis of Linked Data.
Menezes C, Nehme Z, Burchill LJ et al.
Med J Aust·2026·Animal·PubMed →
Novel genetic profile linked to cognitive decline in Hispanics/Latinos.
Hrytsenko Y, Purushotham Y, Li Z et al.
Alzheimers Dement·2026·Animal·PubMed →
Immune responses following myocardial infarction in aged mice.
Melika ET, Ashour D, Appel M et al.
J Mol Cell Cardiol·2026·Animal·PubMed →
Single-channel characteristics and regulation of endogenously expressed cation channels in human cardiac microvascular endothelial cells and human aortic endothelial cells.
Yu L, Bala N, LaDisa JF et al.
Biochim Biophys Acta Gen Subj·2026·Animal·PubMed →
Proteomic Profiling of Post-COVID -19 Sequelae.
Golriz Khatami S, Baumkötter R, Köck T et al.
Mol Cell Proteomics·2026·Animal·PubMed →
Longitudinal trajectories of the C-reactive protein-triglyceride-glucose index and frailty progression in two nationwide prospective cohorts.
Liu ZY, Sun CL
Maturitas·2026·Animal·PubMed →
Stroke Prevention in the Longevity Era: An Integrated Framework for Cerebrovascular and Biological Aging.
Saposnik G, Estol CE
Stroke·2026·Animal·PubMed →
Cardiovascular risk factors and regional neuropathology in autopsy-confirmed Alzheimer disease.
Garcia D, Wang HP, Saito N et al.
J Neuropathol Exp Neurol·2026·Animal·PubMed →
Hypomorphic STING1/TMEM173 variants may support immuno-metabolic resilience in aging people living with HIV.
Zanella I, Fornari C, Cesanelli F et al.
Geroscience·2026·Animal·PubMed →
Shikonin attenuates doxorubicin-induced myocardial senescence and fibrosis in association with improved redox and mitochondrial homeostasis.
Ren GQ, He ML, Guo YQ et al.
Mol Biol Rep·2026·Animal·Longevity·PubMed →
Synergistic effects of cerebrovascular reactivity and gray matter volume on executive function in aging.
Zhang J, Jia X, Zhang Y et al.
J Alzheimers Dis·2026·Animal·PubMed →
Carotid arterial stiffness is associated with selective glomerular hypofiltration of middle-sized molecules in type 2 diabetes.
Laucyte-Cibulskiene A, Kurien Thomas E, Lindberg I et al.
Diab Vasc Dis Res·2026·Animal·Glycemic Control·PubMed →
Autophagy Flux Is Remodeled Sex- and Cell Type-Specifically During Human Aging, and Is Linked to Reduced Physical Function in Older Adults.
Moreno TM, Heimler SR, Moran RJ et al.
Aging Cell·2026·Animal·Longevity, Tissue Remodeling·PubMed →
A 9-year longitudinal investigation into physiological aging in highly active older adults.
Fathi AS, Francis T, Milbourn E et al.
Geroscience·2026·Animal·PubMed →