Research Index

Tesofensine Research Index

PSI surfaces 50 peer-reviewed studies on Tesofensine, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.

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50 studies

Management and optimisation in the preoperative phase for patients with a fractured hip.

Meermans G, van Egmond JC

EFORT Open Rev·2026·Human·PubMed →

Gender differences in sleep quality and its associated factors in patients with hypertension: a cross-sectional study.

Li H, Ching SM, Liong SF et al.

BMC Public Health·2026·Human·PubMed →

Dose-Related Effects of Different Tai Chi Styles Versus Traditional Community-Based Exercises on Cardiometabolic Health and Physical Function in Middle-Aged and Older Adults: Randomized Controlled Trial.

Qiu J, Wang J, Song X et al.

JMIR Aging·2026·Human·PubMed →

Natural history of thyroid function in ageing: an individual participant data analysis of 137 488 participants from 31 prospective cohort studies.

Xu Y, Hysaj O, Qi X et al.

Lancet Diabetes Endocrinol·2026·Human·PubMed →

Frailty status and mortality among patients with cardiometabolic diseases in an international multi-cohort study.

Ren R, Zhang Y, Du M et al.

iScience·2026·Human·PubMed →

Feasibility of Integrated Transcranial Doppler Ultrasound-Near-Infrared Spectroscopy to Measure Cerebral Haemodynamics in Dementia, Delirium, and Depression (the VESPAR Project): A Pilot Study.

Edwards O, Nicholls JK, Desai B et al.

J Neurosci Methods·2026·Human·PubMed →

Care Coordination and Hospitalization in Older Adults With or at Risk for Cardiovascular Disease: A Randomized Clinical Trial.

Kern LM, Aucapina JE, Banerjee S et al.

JAMA Netw Open·2026·Human·Cardiovascular Risk·PubMed →

Heart Attack Education and EMS Response in High-Risk, Low EMS Usage Areas: A Stepped-Wedge Cluster-Randomized Trial.

Bray JE, Nehme Z, Finn JC et al.

JAMA Netw Open·2026·Human·PubMed →

Prescribing Cascade as a Therapeutic Error: A Danger for Geriatric Patients with Multimorbidity.

Bryła A, Woroń J, Miedziaszczyk M et al.

Geriatrics (Basel)·2026·Human·PubMed →

Anesthetic Considerations in Geriatric Patients Undergoing Cataract Surgery: A Review of Perioperative Management and Outcomes.

Prado Fonseca SJ, Araya Padilla FM, Rodríguez N et al.

Cureus·2026·Human·PubMed →

Malnutrition and mortality in patients≥75 years with chronic heart failure.

Díez-Villanueva P, Jiménez-Méndez C, Esteban-Fernández A et al.

Med Clin (Barc)·2026·Human·PubMed →

Three Low-Dose Antihypertensive Agents in a Single Pill after Intracerebral Hemorrhage.

Trident Research Group, Anderson CS, Chow CK et al.

N Engl J Med·2026·Human·Cardiovascular Risk·PubMed →

Risk of severe cardiovascular events and incidence rate of cardiopulmonary events among patients with COPD in China: a retrospective cohort study.

Liu Z, Cheang I, Chen Y et al.

BMJ Open·2026·Human·Cardiovascular Risk·PubMed →

Association between Physical Function and Incidence of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study.

Pae BJ, Li L, Wood K et al.

medRxiv·2026·Animal·PubMed →

Clinical and imaging phenotypes.

Benfari G, Margonato D, Metra M et al.

Eur Heart J Suppl·2026·Animal·PubMed →

White matter hyperintensities, retinal vascular calibre and changes in age-related hearing loss.

Clark DPQ, Tran C, Hussain SM et al.

Brain Commun·2026·Animal·PubMed →

Associations of Different Definitions of Prediabetes and Diabetes with All-Cause and Cause-Specific Mortality: A Nationally Representative Cohort Study.

Zhang M, Qiu Z, Wang Y et al.

Mil Med Res·2026·Animal·Glycemic Control·PubMed →

Association Between Discrimination in Health Care and ASCVD Among Middle-Aged and Older Adults in the United States.

Green MD, O'Brien EC, Navar AM et al.

Circ Popul Health Outcomes·2026·Animal·PubMed →

Association Between Motor Difficulties and Osteoarthritis in Ageing Adults: Evidence From Propensity Score Matching.

Karim A, Hussain MA, Ahmad F et al.

Australas J Ageing·2026·Animal·Osteoarthritis, Longevity·PubMed →

CAR-T cells targeting fibroblast activation protein eliminate pathological fibroblasts and preserve cardiac function in a Duchenne Muscular Dystrophy murine model.

Marigny C, Revet G, Berger A et al.

Stem Cell Res Ther·2026·Animal·PubMed →

Association between adverse childhood experiences and cardiovascular disease risk in cardiovascular kidney metabolic syndrome stages 0 to 3.

Sun M, Wang Y, Gao J et al.

Sci Rep·2026·Animal·PubMed →

Admixture-informed polygenic risk reporting using the ePRS framework.

Huang YJ, Kurniansyah N, Goodman MO et al.

Nat Commun·2026·Animal·PubMed →

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.

Huerta-Chagoya A, Kim J, Mandla R et al.

Lancet Diabetes Endocrinol·2026·Animal·PubMed →

The association of accelerated biological aging with heart diseases in adults aged 40-69 years: a population-based cohort study.

Wang R, Chen Y, Yin X et al.

Heart Lung·2026·Animal·PubMed →

Association of 24-Hour Blood Pressure Variability With Cognition and Brain MRI Markers of Structural Change in Adults in Mid- to Late-Life.

Gibson M, Snelson M, Rowsthorn E et al.

Neurology·2026·Animal·Cognitive Enhancement·PubMed →

Divergent Roles of Skeletal Muscle 11β-HSD1 in Age-Related and Chronic Kidney Disease-Associated Sarcopenia.

Sagmeister MS, Crastin A, Welsh B et al.

Eur J Endocrinol·2026·Animal·PubMed →

Mitral Annular Calcification.

Oprysko C, Prabhakar C, Berman L et al.

Cardiol Rev·2026·Animal·PubMed →

The Medium Chain Fatty Acid Octanoate is a Beneficial Fuel for the Failing Heart.

Gorgodze N, Matsuura TR, Nisini N et al.

Am J Physiol Heart Circ Physiol·2026·Animal·PubMed →

Same Support, Different Outcomes: Sex Differences in Complex PCI With Mechanical Circulatory Support.

Thakker R, Joodi G, Nanna MG

JACC Adv·2026·Animal·PubMed →

Plasma Dilution After Myocardial Ischemia-Reperfusion Injury Promotes Cardiac Repair, Heart Performance, and Recovery of Motor Function and Endurance in Old Mice.

Cruz JMC, Alzalzalee R, Yeung H et al.

Aging Cell·2026·Animal·PubMed →

Elevated Metastasis-Associated lung adenocarcinoma transcript 1 (MALAT1) expression predicts coronary artery disease severity as a potential biomarker for risk stratification: a cross-sectional study.

Zheng J, Ludin AFM, Rajab NF et al.

Ann Med·2026·Animal·PubMed →

Endothelial DNA Damage Orchestrates Cardio-Kidney-Metabolic Dysfunction Through Endothelin-1 Signaling.

Ito W, Nakamichi R, Hishikawa A et al.

Arterioscler Thromb Vasc Biol·2026·Animal·PubMed →

Association between physical activity and cardiovascular-kidney-metabolic syndrome in older Chinese adults: a nationwide, cross-sectional study.

Liu Q, Shen J, Zhang Y et al.

J Glob Health·2026·Animal·Metabolic Syndrome, Cardiovascular Risk·PubMed →

Stroke Riskometer™ Mobile Phone Application improves Stroke Knowledge in a Randomised Controlled Trial.

Wake AD, Krishnamurthi R, Fraser BJ et al.

Int J Stroke·2026·Animal·PubMed →

Cardiac fibroblast-derived CCN1 aggravates diabetic cardiomyopathy through ITGAV-ITGB1/integrin αvβ1-mediated autophagy inhibition.

Hu BA, Zhang L, Song M et al.

Autophagy·2026·Animal·PubMed →

Cardiovascular-Related Polypharmacy and Its Association with Liver and Kidney Function: A Cross-Sectional Study Using Primary Care Data.

Trin C, Koh HJW, Orman Z et al.

Drugs Aging·2026·Animal·PubMed →

Association between cardiovascular disease risk factors and white matter lesions: The Tohoku Medical Megabank Cohort Study.

Satake M, Chiba I, Kogure M et al.

J Atheroscler Thromb·2026·Animal·PubMed →

Reliability of resting-state photoplethysmogram-based pulse rate variability in lifespan samples: Implications for cardiovascular research.

Han X, Li X, Volodarskiy A et al.

Physiol Meas·2026·Animal·PubMed →

The Influence of Accelerated Aging-Related Cardiac Remodeling on Cardiovascular Outcomes: an observational study.

Lv Z, Li K, Liu C et al.

J Gerontol A Biol Sci Med Sci·2026·Animal·PubMed →

Unequal healthy ageing trajectories across Europe: socioeconomic development and age-related disease burden in the European Union and South-Eastern European countries.

Kovacs N, Piko P, Major D et al.

Geroscience·2026·Animal·PubMed →

Effect of repeated hot water immersion on cognitive performance, cerebrovascular function, sleep and biomarkers of neurodegeneration in older adults.

Piccolo DD, Corbett J, Costello JT et al.

Exp Physiol·2026·Animal·PubMed →

Aligning Coronary Stent Trial Enrollment With the U.S. Intended-Use Population: Implications of Site Selection.

Batchelor WB, Califf R, Mehran R et al.

J Am Coll Cardiol·2026·Animal·PubMed →

IFN-γ and IL-17A Exhibit Opposing Roles in Age-Related Blood Pressure Dysregulation.

Muchaili L, Sinamwenda EN, Hamooya BM et al.

Int J Hypertens·2026·Animal·PubMed →

The effects of metformin and exercise training on cardiorespiratory, blood pressure, and metabolic adaptations across the spectrum of glucose dysregulation: a systematic review and meta-analysis.

Etayo-Urtasun P, Sáez de Asteasu ML, Izquierdo M

EClinicalMedicine·2026·Animal·PubMed →

Prognostic value of PREVENT, PCE, and social determinants of health for cardiovascular mortality in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study.

Downie CG, Joo J, Hashemian M et al.

BMC Public Health·2026·Animal·PubMed →

Dietary intake and epigenetic aging in an African population: food groups, dietary patterns, and plant-based diets in the RODAM study.

Auwerda NCS, Mungamba MM, Van der Linden E et al.

BMC Med·2026·Animal·PubMed →

Peripheral vascular function, including endothelium-dependent measures, and dementia risk: The Framingham Heart Study.

Tao Q, Han J, Ang TFA et al.

Alzheimers Dement·2026·Animal·PubMed →

Longitudinal associations of cardiovascular-kidney-metabolic syndrome with midlife or late-life mental disorders and dementia, and the mediating role of metabolomic signature.

Zhao X, Lin Z, Zhang H et al.

Commun Med (Lond)·2026·Animal·PubMed →

A curated arterial stiffness dataset for vascular age prediction in China.

Chen X, Ding P, He M et al.

Sci Data·2026·Animal·PubMed →

SIRT7 links H3K36ac epigenetic regulation with genome maintenance in the mouse testis.

Guitart-Solanes A, Romero M, Gamez-Garcia A et al.

Nat Commun·2026·Animal·PubMed →