TB-500 — Indexed Studies

Recombinant human thymosin beta 4 improves ischemic cardiac dysfunction in mice and patients with acute ST-segment elevation myocardial infarction after reperfusion.

Zhang Y, Dong Q, Bian X et al.

The Prognostic Significance of TMSB4X in Glioma Patients.

Li S, Fan T, Hao Z et al.

Association of serum thymosin β4 with malnutrition-inflammation-atherosclerosis syndrome in peritoneal dialysis patients: a cross-sectional study.

Tian J, Zhang R, Zhu N et al.

Hypermethylation of thymosin β4 predicts a poor prognosis for patients with acute-on-chronic hepatitis B liver failure.

Wang H, Yin YP, Wang ZL et al.

Role of Thymosin Beta 4 in the diagnosis of Nonalcoholic Fatty Liver and its relation to Metabolic Syndrome in Egyptian patients.

Ahmed AE, Ibrahim WA, Nabil ZM et al.

Hypomethylation of thymosin β4 promoter is associated with glucocorticoid therapy in patients with acute-on-chronic hepatitis B-induced liver failure.

Wang H, Qian Y, Wang JW et al.

Thymosin beta-4 improves endothelial function and reparative potency of diabetic endothelial cells differentiated from patient induced pluripotent stem cells.

Su L, Kong X, Loo S et al.

Fetal programming of atherosclerosis: may the barker hypothesis explain the susceptibility of a subset of patients to develop stroke or cardiac infarct?

Gerosa C, Faa G, Fanni D et al.

Association between Thymosin beta-4, acute kidney injury, and mortality in patients with sepsis: An observational cohort study.

Zhang J, Long M, Sun Z et al.

A first-in-human, randomized, double-blind, single- and multiple-dose, phase I study of recombinant human thymosin β4 in healthy Chinese volunteers.

Wang X, Liu L, Qi L et al.

Acupuncture Regulates Serum Differentially Expressed Proteins in Patients with Chronic Atrophic Gastritis: A Quantitative iTRAQ Proteomics Study.

Li F, Yang B, Liu Y et al.

Identification of altered protein expression in major depressive disorder and bipolar disorder patients using liquid chromatography-tandem mass spectrometry.

Kim H, Rhee SJ, Lee H et al.

F-Actin is associated with a worsening qSOFA score and intensive care unit admission in emergency department patients at risk for sepsis.

Belsky JB, Filbin MR, Rivers EP et al.

Comparative Proteomic Analysis of the Secretome of Control and BRAF/MEK Inhibitor-Resistant Melanoma Cells.

Simiczyjew A, Surman M, Kot M et al.

A revised model of nuclear actin import: Importin 9 competes with cofilin, profilin, and RanGTP for actin binding.

Keplinger AJ, Srinivasan PA, Christensen SM et al.

Thymosin β4-derived peptides alleviate neuroinflammation and neurite atrophy in both in vitro models and in vivo 5 × FAD mice: A potential therapy for memory improvement in Alzheimer's disease.

Ou H, Chen R, Zhou L et al.

Thymosin β4 stabilizes hypoxia induced brain microvascular endothelial cell dysfunction through S1PR1 dependent mechanisms.

Stewart WG, Hejl CD, Guleria RS et al.

Thymosin β4 released by mast cells under stress conditions impairs intestinal epithelial barrier via IL22RA1/JAK1/STAT3 signaling in irritable bowel syndrome.

Sun YS, Bai XQ, Sun KD et al.

Engineered Tandem Thymosin Peptide Promotes Corneal Wound Healing.

Nguyen J, Verma S, Vuong VT et al.

Tβ4-17 peptide enhances the chemo-sensitivity of ovarian cancer cells to DDP by affecting NF-κB signaling pathway.

Guo L, Wang H, Li N et al.

Mechanistic study of the Tβ4/SLC7A11 signaling pathway regulating breast cancer evolution.

Jin Z, Li H, Li J et al.

Electron Capture Dissociation for Discovery Top-Down Proteomics of Peptides and Small Proteins on Chromatographic Time Scales.

Manly LS, Roberts AM, Beckman JS et al.

Thymosin beta 4 as an Alzheimer disease intervention target identified using human brain organoids.

Zeng PM, Sun XY, Li Y et al.

Comparative effects of dietary sodium butyrate and tributyrin on broiler chickens' performance, gene expression, intestinal histomorphometry, blood indices, and litter.

Ismael E, Kamel S, Elleithy EMM et al.

Injectable Thymosin β4-Modified Hyaluronic Acid Hydrogel with Exosomes for Stem Cell Homing and Neuronic-Angiogenic-Osteogenic Coupled Cranial Repair.

Xi Y, Zhang Z, Zhao Z et al.

Thymosin Beta-4 Modulates Cardiac Remodeling by Regulating ROCK1 Expression in Adult Mammals.

Maar K, Thatcher JE, Karpov E et al.

Thymosin β4 Regulates Tissue Inflammatory Response in Mouse Nonalcoholic Fatty Liver Disease by Promoting Macrophage M2-Type Polarization.

Zhu Z, Liao Y, Mou Q et al.

Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing.

Ding Y, Wang J, Li J et al.

Living myocardial slices as a model for testing cardiac pro-reparative gene therapies.

Caliandro R, Husetić A, Ligtermoet ML et al.

Study of Intracellular Peptides of the Central Nervous System of Zebrafish (Danio rerio) in a Parkinson's Disease Model.

Fiametti LO, Franco CA, Nunes LOC et al.

Retraction: The role of thymosin beta 4 on odontogenic differentiation in human dental pulp cells.

PLOS One Editors

Plasmacytoid dendritic cells alleviate allergic asthma via airway epithelial cell-dependent thymosin β4 expression.

Li Y, Chen Z, Han M et al.

Exploring the Relationship Between Thymosin β4 Protein and First Myocardial Infarction on the Basis of Proteomics.

Lu Z, Liu Q, Fan Y et al.

CCN5 suppresses injury-induced vascular restenosis by inhibiting smooth muscle cell proliferation and facilitating endothelial repair via thymosin β4 and Cd9 pathway.

Zhang Q, Li H, Zhuang T et al.

Identification of glutamine as a potential therapeutic target in dry eye disease.

Chen X, Zhang C, Peng F et al.

Enhancing fat graft survival: thymosin beta-4 facilitates mitochondrial transfer from ADSCs via tunneling nanotubes by upregulating the Rac/F-actin pathway.

Zhang X, Lin Y, Li H et al.

Inhaled exogenous thymosin beta 4 suppresses bleomycin-induced pulmonary fibrosis in mice via TGF-β1 signalling pathway.

Yu R, Li S, Chen L et al.

TMSB4X is a regulator of inflammation-associated ferroptosis, and promotes the proliferation, migration and invasion of hepatocellular carcinoma cells.

Tang L, Jin Y, Wang J et al.

Proteomic analysis of the human amniotic mesenchymal stromal cell secretome by integrated approaches via filter-aided sample preparation.

Muntiu A, Papait A, Vincenzoni F et al.

Thymosin β4 promotes zebrafish Mauthner axon regeneration by facilitating actin polymerization through binding to G-actin.

Song Z, Han A, Hu B

Activation of pro-resolving pathways mediate the therapeutic effects of thymosin beta-4 during Pseudomonas aeruginosa-induced keratitis.

Wang Y, Banga L, Ebrahim AS et al.

Equine Doping Controls of Thymosin β 4: A Population Study and Strategy for Misuse Detection.

Delcourt V, Garcia P, Chabot B et al.

Therapeutic potential of thymosin beta 4 in a variety of diseases.

Ye C, Dai Q, Deng L et al.

The subcommissural organ regulates brain development via secreted peptides.

Zhang T, Ai D, Wei P et al.

Small Spleen Peptides (SSPs) Shape Dendritic Cell Differentiation through Modulation of Extracellular ATP Synthesis Profile.

Wixler V, Leite Dantas R, Varga G et al.

The subcommissural organ regulates brain development via secreted peptides.

Zhang T, Ai D, Wei P et al.

The fascinating theory of fetal programming of adult diseases: A review of the fundamentals of the Barker hypothesis.

Faa G, Fanos V, Manchia M et al.

In Vitro Study of Thymosin Beta 4 Promoting Transplanted Fat Survival by Regulating Adipose-Derived Stem Cells.

Li W, Yang Y, Lin Y et al.

Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro.

Rahaman KA, Muresan AR, Min H et al.

Thymosin β4 Regulates the Differentiation of Thymocytes by Controlling the Cytoskeletal Rearrangement and Mitochondrial Transfer of Thymus Epithelial Cells.

Ying Y, Tao N, Zhang F et al.