Thymogen — Indexed Studies

First clinical use of the kisspeptin analog TAK-683 in the treatment of a follicular cyst in a goat: case report.

Uyanık G, Yüksel M, Kara F et al.

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review.

Menekse B, Ucgul E, Bakir A et al.

Comparative Analysis of Kisspeptin Levels and KISS1 Gene Polymorphism in Patients with Polycystic Ovary Syndrome (PCOS): Correlation with the Luteinizing Hormone-Follicle-Stimulating Hormone Ratio and PCOS-Associated Variables.

Talukdar C, Choudhary SS, Talukdar PM et al.

Effect of post-mating TAK-683 (Kisspeptin analog) treatment on luteal morphology and function in suckling goats with lactational anestrus.

Uyanık G, Yüksel M, Abay M et al.

Intravenous kisspeptin 112-121 bolus does not acutely impact circulating vasopressin in humans.

Galbiati F, Plessow F, Plummer L et al.

Serum Kisspeptin levels in patients undergoing maintenance hemodialysis: a case-control study protocol.

Yang B, Zheng N, Shao Q et al.

Concentration-QTc Modeling to Support Clinical Development of Fezolinetant.

Nielsen JC, Saito M, Wang X et al.

Effect of kisspeptin with or without cabergoline on the estrus cycle and reproductive hormones in female dogs.

Bozkurt G, Agaoglu AR, Aslan S et al.

Evaluation and Treatment of Patients With Hypothalamic Hypogonadism.

Himel R, Keefe D

Evaluation of Betatrophin, Chemerin, and Kisspeptin Levels in Acromegaly Patients.

Cayan DA, Topsakal S, Avci E

Intranasal kisspeptin administration rapidly stimulates gonadotropin release in humans.

Mills EG, Silva MSB, Delli V et al.

Corrigendum to "Kisspeptin-54 attenuates oxidative stress and neuronal apoptosis in early brain injury after subarachnoid hemorrhage in rats via GPR54/ARRB2/AKT/GSK3β signaling pathway" [Free Radic Biol Med.171 (2021) 99-111].

Huang Y, Guo Y, Huang L et al.

GABA receptor modulation of arcuate kisspeptin neuron bursting and synchronization activity in female mice.

Eddleston T, Morris PG, Herbison AE

Molecular and functional characterization of the kisspeptin receptor Kissr3 in the large yellow croaker (Larimichthys crocea).

Yuan H, Huang B, Zhang R et al.

Robust serotonin activation of the kisspeptin GnRH pulse generator in male and female mice.

Morris PG, Liu X, Birt E et al.

The Expression of Kisspeptin Receptor, Catsper 3 and Acrosome Integrity in Oligozoospermic and Normozoospermic Individuals.

Ünlükal N, Aniç S, Dursunoğlu D et al.

Cadmium-Induced Neuroendocrine Alterations: Gene Expression of the Kisspeptin-GnRH Axis and Delayed Puberty in Male Rats.

Arteaga-Silva M, Cornejo de la Concha EM, Landero-Huerta DA et al.

Kobayashi Award 2024: Cyclic regulation of the reproductive neuroendocrine system in fish: Using migratory fish as a model.

Ando H

Effects of Microplastics on the Central Reproductive Neuroendocrine System in a Sheep Model.

Młotkowska P, Osuch B, Marciniak E et al.

Microglia Rank signaling regulates GnRH neuronal function and the hypothalamic-pituitary-gonadal axis.

Collado-Sole A, Borjini N, Zhai J et al.

Neuroendocrine effects of exogenous adropin administration on the hypothalamic pituitary testicular axis in male rats.

Eraslan E, Tanyeli A, Güler MC et al.

Novel KISS1 Gene Mutation Leading to Male Hypogonadotropic Hypogonadism.

Wittner L, Mahindrakar S, Yasin A et al.

Progestogen priming is not essential to trigger ovulation in seasonal anoestrus ewes injected twice with a synthetic kisspeptin analogue.

Lomet D, Robert V, Decourt C et al.

Kisspeptin Restores Placental mTOR Signaling and Improves Glucose Homeostasis Mediators Disrupted by Maternal Hypothyroidism in Rats.

Santos BR, Dos Anjos Cordeiro JM, Santos LC et al.

Investigation of Radiolabeled KISS1R Ligands as Promising Tools for Diagnosis and Treatment of Triple-Negative Breast Cancer.

Taş H, Schäfer M, Shuja-Uddin A et al.

GPR54 regulates non-small cell lung cancer development via dopa decarboxylase.

Hwang HH, Lee SY, Lee C et al.

Targeting the NR5A1-KISS1R-EMT axis with a small-molecule inhibitor suppresses lung adenocarcinoma progression and metastasis.

Wang D, Hui K, Yuan C et al.

Sodium benzoate induces reproductive toxicity via hormonal disruption, ovarian damage and altering kisspeptin/RFRP-3 expression.

Khan S, Attaullah M, Zubair M et al.

In vitro differentiation of the hypothalamic KNDy neuron, a master regulator for reproduction, from mouse embryonic stem cells.

Miyake N, Suga H, Osuka S et al.

Direct adverse effects of fipronil sulfone, diisopentyl phthalate and disperse red 60 on zebrafish hepatocytes.

Leite BA, de Oliveira DP, Unniappan S

Functional interactions between anteroventral periventricular kisspeptin neurons and gonadotropin-releasing hormone neurons in female mice.

Starrett JR, Krasner D, Phillips CD et al.

Evolution of neurohormone function revealed by actions of kisspeptin-type peptides in an echinoderm.

Islam T, Yañez-Guerra LA, Semmens DC et al.

Preoptic kisspeptin-nNOS-GnRH (KiNG) neuronal network regulates LH rhythmicity through activation-inhibition in mice.

Delli V, Moulinier M, Lazaridou AM et al.

Kisspeptin improves local ovarian insulin resistance in PCOS by modulating the PI3K/AKT/GLUT4 signaling pathway.

Sun N, Sun P, Sun L et al.

High-Fat Diet Induces Epigenetic and Metabolic Changes in Kisspeptin Neurons in Association with Obesity and Male Secondary Hypogonadism.

Fang R, Carroll RS, Kaiser UB

Activity Changes of the Hypothalamus-Pituitary Hormonal Axis in Peripubertal Female Rats.

Jeon EY, Lee SH

Evidence for KISS-1 nuclear translocation and PI3K/AKT signaling in the ultrastructurally and morphometrically analyzed human endometriosis.

Hamutoğlu R, Kaloğlu C, Bulut HE et al.

Therapeutic Effects of Phytoestrogen Naringenin in Polycystic Ovary Syndrome (PCOS): Involvement of Kisspeptin and Calcitonin Gene Related Peptide Signalling Pathways.

Habibi M, Mahmoudi F, Haghighat K et al.

Tissue-Slice Organ-on-Chip Culture of Hypothalamic and Pituitary of Lambs─The Role of Phoenixin-20 as a Modulator of Gonadotrophic Axis.

Szlis M, Przybył BJ, Wójcik-Gładysz A

Kisspeptin mediates the impact of chronic psychological stress on reproductive and metabolic dysregulation in polycystic ovary syndrome: evidence from human and rat models.

Mo T, Qiu Y, He S et al.

KNDy neurons as an indirect target of insulin-like growth factor-1.

Silva JDN, de Sousa LMM, de Sousa ME et al.

Citalopram-induced decrease of CLOCK-ir and BMAL1-ir kisspeptin neurons in the anteroventral periventricular nucleus of adult male mice.

Putteeraj M, Soga T, Parhar IS

Haploinsufficiency of Sox2 causes fewer GnRH neurons and delayed puberty in mice.

Cassin J, Dunn GA, Nguyen RD et al.

Kisspeptins inhibit ectopic endometrial cell invasion and angiogenesis by suppressing PI3K/AKT signaling pathway via CREB5 in endometriosis.

Kong L, Yushanjiang S, Nie L et al.

Inhibitory effects of a κ-opioid receptor agonist and neurokinin-3 receptor antagonist on testosterone secretion in male rats.

Sakono T, Munetomo A, Sato M et al.

Integrated transcriptomics and miRNA-mRNA network analysis reveals Kisspeptin-10 mediated regulation of EMT and apoptosis in glioblastoma.

Shah H, Mohan AM, Shah R et al.

The Kisspeptin analogue C6 induces more synchronized ovulation than eCG in the transition period to breeding season in Corriedale ewes.

Bottino JP, Ungerfeld R, Taira AR et al.

Dual role of Kisspeptin-10 in modulating neuroinflammation: Downregulation of NLRP3 inflammasome activation and Caspase-1-mediated pyroptosis, and activation of BAG3-dependent aggrephagy in microglial cells.

Kalkan ÖF, Erdem Ş, Erdem M et al.

The protective effects of dapagliflozin on cisplatin-induced ovarian toxicity via NRF2-HO-1 pathway and TNF-α/Cas3 signaling.

Sarman E, Asci H, Selcuk E

Direct effect of kisspeptin on steroidogenesis, proliferation and apoptosis in Tan sheep ovarian granulosa cells.

Song W, Dai T, Yang D et al.