Research Index
Substance P Research Index
PSI surfaces 50 peer-reviewed studies on Substance P, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
50 studies
Thalidomide-mediated immunomodulation in a patient with IL-10RA deficiency-associated very early-onset inflammatory bowel disease.
Ren A, Zeng Q, Zhang B et al.
Front Immunol·2026·Human·GI Protection·PubMed →
Low-FREquency Deep TRanscranial Magnetic Stimulation in ACute Ischaemic StrokE within 48 Hours (RETRACE-I): rationale and design of a randomised, multicentre, open-label, blinded endpoint trial.
Ding L, Lv S, Wang W et al.
Stroke Vasc Neurol·2026·Human·PubMed →
Synovial Biomarker Modulation and Clinical Response to Umbilical Cord-Derived MSC Treatment in Knee Osteoarthritis: A Case Series Study.
Švajger U, Kolar M, Pompe B et al.
Cartilage·2026·Human·PubMed →
The potential clinical significance of immunomodulation of immune and inflammatory responses involving selected adipokines in patients with ovarian cancer - preliminary studies.
Stępień S, Morawiec ML, Smycz-Kubańska M et al.
Front Oncol·2026·Human·PubMed →
Safety and Pharmacokinetics of SRN001, a Novel siRNA Drug Targeting Amphiregulin via the SAMiRNA Platform.
Park J, Lee S, Chung JY et al.
Drug Des Devel Ther·2026·Human·PubMed →
Analysis of differentially expressed genes related to acute lung injury and their role in metabolic pathways: An integrative study using GEO data.
Yang Y
Medicine (Baltimore)·2026·Animal·PubMed →
Enhanced tumor control in non-small cell lung cancer using intensity-modulated radiotherapy combined with microwave hyperthermia: A retrospective study.
Li W, Liu X, Chen W
Medicine (Baltimore)·2026·Animal·PubMed →
High-dimensional multiomics reveals perturbations to IL-6/IL-6R axis and RUNX3 in CD4(+) T cells during third-trimester pregnancy.
Habel JR, Nguyen THO, de Alwis N et al.
Clin Transl Immunology·2026·Animal·PubMed →
Comparative Analysis of Tumor Microbiota Identifies a Metastatic-Specific Bacterial Signature, Highlighting Streptococcus spp. As the Predominant Hub across Cancers.
Todorovic N, Bertorello S, Nannini G et al.
Oncol Res·2026·Animal·PubMed →
A Conversational Artificial Intelligence Framework for Comparative Pathway-Level Profiling of Sézary Syndrome and Primary Cutaneous CD8 (+) Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma (PCAECTCL).
Diaz FC, Waldrup B, Carranza FG et al.
medRxiv·2026·Animal·PubMed →
Ionizing radiation expands a p90RSK-activated patrolling monocyte subset: modulation by colchicine.
Imanishi M, Samanthapudi VSK, Le NT et al.
Front Cardiovasc Med·2026·Animal·PubMed →
Laetiporus sulphureus polysaccharides mitigate colitis by reshaping the gut microbiota and regulating immune responses.
Ali S, Alioui Y, Khan I et al.
Front Pharmacol·2026·Animal·PubMed →
Thymelaea hirsuta (L.) Endl. extract attenuates NLRP3 inflammasome activation via modulation of ATPase activity.
Lee S, Jang S, Lee H et al.
Front Pharmacol·2026·Animal·PubMed →
Chaihu-Wendan Decoction alleviates obesity through PTEN-mediated uncoupling of metabolic signaling and macrophage activation.
Ye B, Zhou Y, Wang Y et al.
Front Endocrinol (Lausanne)·2026·Animal·Weight Loss, Glycemic Control·PubMed →
m6A Methyltransferase METTL3 Regulates Inflammatory and Immune Microenvironments in Renal Cell Carcinoma via Modulation of the PI3K/AKT Pathway.
Cheng T, Xu W, Zha Z et al.
Int J Genomics·2026·Animal·PubMed →
Preclinical Evaluation of Radium-223 and Immune Checkpoint Inhibitors Using an Immune-Competent Model of Prostate Cancer Bone Metastases.
Lilieholm C, Adeniyi AO, Kwon O et al.
Precis Oncol·2026·Animal·PubMed →
Human respiratory syncytial virus regulates the expression of interferon-stimulated genes through modulation of fibrillarin.
Ulloa-Aguilar JM, Cruz-Holguin VJ, Benítez-Zeferino YR et al.
Front Cell Infect Microbiol·2026·Animal·PubMed →
A comparative analysis of CDK1 expression in normal mucosa, oral epithelial dysplasia and oral squamous cell carcinoma - An immunohistochemical study.
Angeline J, Rao GN, Sachindharan N et al.
J Oral Maxillofac Pathol·2026·Animal·PubMed →
Protective role of mucosa-associated invariant T cells in sepsis-related liver injury.
Bu W, Ji Q, Yao Y et al.
Front Immunol·2026·Animal·Liver Protection, Anti-Inflammatory·PubMed →
TLR2 activation potentiates P-glycoprotein-mediated methotrexate efflux and enhances cytotoxicity of human NK cells against acute lymphoblastic leukemia.
Álvarez-Carrasco P, Basurto-Olvera P, Jiménez-Hernández E et al.
Front Immunol·2026·Animal·PubMed →
The transmembrane IL-15 isoform expressed on human melanoma cells triggers modulatory effects on tumor progression upon stimulation with the soluble IL-15Rα chain.
Forcelloni S, Giron-Michel J, Del Boccio P et al.
Front Immunol·2026·Animal·PubMed →
Enterococcus faecium HDRsEf1 induces changes in gut microbiota and metabolites to maintain host health.
Feng S, Tian C, Li J et al.
Front Immunol·2026·Animal·GI Protection, Anti-Inflammatory·PubMed →
An agent-based learning model integrating sex differences in renal cell carcinoma.
Merelli E, Taha T, Caputo M et al.
Front Immunol·2026·Animal·PubMed →
Immune-Enhancing Effects of IBP35, a Combination of Lactiplantibacillus plantarum and Ligilactobacillus salivarius, in Macrophages and Cyclophosphamide-Induced Immunosuppressed Mice.
Lee HB, Lee J, Jeong K et al.
Food Sci Nutr·2026·Animal·PubMed →
An exploration of GuaLouQuMaiWan related novel prognostic model and search for potential compound pachymic acid in bladder cancer.
Teng Q, Cheng S, Chen J et al.
Front Oncol·2026·Animal·PubMed →
Activation-gated, T cell-restricted silencing of Dapk1 enhances Bacille Calmette-Guérin-elicited protective CD4(+) memory.
Liu Z, Liu W, Zhao C et al.
iScience·2026·Animal·PubMed →
Immune-mediated microbial interference governs Borrelia colonization of the tick gut.
Hodžić A, Kunert M, Juračić M et al.
iScience·2026·Animal·PubMed →
Spatial Confinement-Engineered Heteronuclear Diatomic Nanozymes for Modulation of Immune Homeostasis in Rheumatoid Arthritis.
Wu M, Li H, Wang P et al.
Small·2026·Animal·PubMed →
Exploring the immune-modulatory role of melatonin in head kidney and spleen cells of freshwater snakehead teleost, Channa punctatus.
Khan SF, Shree S, Tripathi MK
J Fish Biol·2026·Animal·PubMed →
Dietary variations drive divergent phenotypic, transcriptomic, and metatranscriptomic profiles in Biomphalaria glabrata, a schistosomiasis vector snail.
Famakinde DO, Lonergan C, Wells D et al.
Parasit Vectors·2026·Animal·PubMed →
The impact of previous brucellosis treatment on the clinical course of neurobrucellosis: a multicentre retrospective study.
Evlice O, Yılmaz E, Kır MH et al.
BMC Infect Dis·2026·Animal·PubMed →
Kynurenic acid as a promising therapeutic agent in renal fibrosis: dual modulation of fibrosis and immune crosstalk.
Sykorova S, Krivy J, Hadova K et al.
Br J Pharmacol·2026·Animal·PubMed →
Endophytic Biostimulant Pyrroloquinoline Quinone Enhances Banana Growth and Primes Immunity Against Fusarium Wilt.
Hung SW, Yu MY, Liu CH et al.
Physiol Plant·2026·Animal·PubMed →
ANKFN1 in skin fibroblasts may modulate mast cell activity and is associated with dupilumab response in atopic dermatitis.
Wei QJ, Lu JR, Xiang WY et al.
Immunol Res·2026·Animal·Wound Healing, Tissue Remodeling·PubMed →
The long noncoding RNA lnc13 restrains inflammatory responses to maintain oral tolerance to gluten.
Yang-Fischer R, Shearer A, Leão FB et al.
Nat Immunol·2026·Animal·PubMed →
Epidemiological impacts of nonpharmaceutical interventions are modulated by immunity exposure trade offs.
Saad-Roy CM, Nielsen BF, Lind ML et al.
Commun Med (Lond)·2026·Animal·PubMed →
Impact of vitamin D deficiency on 6-month culture conversion in nontuberculous mycobacterial pulmonary disease.
Kim TO, Kwak N, Jeon D et al.
Sci Rep·2026·Animal·PubMed →
Bifidobacterium bifidum-derived nanoparticles attenuate alcoholic liver disease via enhanced hepatic phagocytosis and gastrointestinal homeostasis.
Gu Z, Meng S, Yao B et al.
Nat Commun·2026·Animal·PubMed →
Systemic modulation of toll-like receptors, cytokine polarization and inflammasome signaling in dogs with generalized demodicosis.
Dawar P, Singh SK, Srivastava MK et al.
Vet Immunol Immunopathol·2026·Animal·PubMed →
FLASH radiotherapy induces unique immunotranscriptomic profiles compared to conventional dose-rate radiotherapy, despite identical immune infiltration and antitumor efficacy in a murine model of triple-negative breast cancer.
Arrigo A, Brants L, Kramp L et al.
Radiother Oncol·2026·Animal·PubMed →
Mucosal-associated invariant T cells drive bile duct inflammation.
Nordhus KS, Zheng F, Berntsen NL et al.
Cell Mol Gastroenterol Hepatol·2026·Animal·PubMed →
Exploring of the immune-related functions of Glucose regulated protein 94 (GRP94) in Mytilus coruscus.
Wu X, Li J, Xiao W et al.
Fish Shellfish Immunol·2026·Animal·PubMed →
Formulation and biological evaluation of a Perilla frutescens seed oil nanoemulsion: A novel therapeutic agent for alleviating gut-liver axis inflammation.
Ye JY, Zhang W, Qin M et al.
Res Vet Sci·2026·Animal·PubMed →
Bioaccumulative toxicity of butylated hydroxytoluene in Ruditapes philippinarum: Lipid metabolic disruption and inflammatory risk.
Qi R, Wang Q, Li P et al.
J Hazard Mater·2026·Animal·PubMed →
Early gut microbiota transplantation in broiler chicks exerts effects on intestinal health depending on the donor's microbial composition.
Zhao H, Akram MZ, Comer L et al.
Poult Sci·2026·Animal·PubMed →
Lactobacillus plantarum extracellular vesicles inhibit avian reovirus replication via activation of the STING-IRF3 signaling pathway.
Qu G, Zhang X, Zhang S et al.
Poult Sci·2026·Animal·PubMed →
Naringenin alleviates heat stress-induced thymic injury through a triple mechanism of immune modulation, antioxidant defense, and inflammation suppression.
Liao K, Wang L, Luo J et al.
Poult Sci·2026·Animal·PubMed →
Comprehensive integrative analysis of Exosome-associated genes in major depressive disorder: Diagnostic biomarker discovery, immune modulation, and therapeutic implications.
Li Y, Huang J, Miao P et al.
J Psychiatr Res·2026·Animal·PubMed →
The Notch1 signalling pathway promotes Silicotic fibrosis by modulating macrophage polarization in response to crystalline silica.
Guo R, Hu W, Zhang X et al.
Int Immunopharmacol·2026·Animal·PubMed →
Ferroptosis-STING co-activation drives GzmB(+)CD38(+)CD8(+) T-cell expansion to overcome lymphoma immunosuppression.
Zhu X, Zhang D, Zhang J et al.
Biomaterials·2026·Animal·PubMed →