Research Index

Substance P Research Index

PSI surfaces 50 peer-reviewed studies on Substance P, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.

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50 studies

The role of CHIP and pre-treatment neutropenia in patients treated with chimeric antigen receptor T cells for hematological malignancies.

Riedel A, Weiß-Haug A, Merz B et al.

Haematologica·2026·Human·PubMed →

Changes in the concentration of new adipokines in serum and peritoneal fluid of patients with serous ovarian cancer as a target for potential use in new diagnostic and therapeutic strategies.

Stepien S, Smycz-Kubanska M, Wikarek A et al.

Ginekol Pol·2026·Human·PubMed →

Clinical improvement of pemphigus-like mucocutaneous disease in a patient with CLL following initiation of zanubrutinib: a case report.

Li T, Lu C, Kang T et al.

Front Immunol·2026·Human·PubMed →

A single-center open-label, randomized, parallel-group controlled clinical trial on the long-term effect of the treatment with EGb 761 in blood markers of inflammation and neurodegeneration in patients with mild cognitive impairment: ACE-2020-EGb 761.

Morato X, Marquié M, Tartari JP et al.

J Alzheimers Dis·2026·Human·PubMed →

Neonatal high-dose riboflavin attenuates abdominal adiposity and binge eating associated with adipose metabolic remodeling in experimental cerebral palsy.

Silva-Araújo ER, Manhães-de-Castro R, Dos Santos Júnior OH et al.

Nutr Neurosci·2026·Animal·PubMed →

Strategies for Cervical Cancer Treatment using the Regenerative Potentials of Mesenchymal Stem Cells.

Nedunchezhian S, Palaniyandi T, Surendran H et al.

Curr Pharm Des·2026·Animal·PubMed →

Various Protein Receptor Functionality in Wound Healing.

Shahjad, Saxena D, Garg Y et al.

Curr Pharm Des·2026·Animal·PubMed →

Neuroinflammation and Autophagy in Neurodegeneration: Cellular Mechanisms and Therapeutic Strategies.

Verma A, Kushwaha SKS, Kushwaha N et al.

CNS Neurol Disord Drug Targets·2026·Animal·PubMed →

From Postbiotic to Prodrug: Chemical Strategies to Widen the Therapeutic Potential of Butyric Acid.

Kapoor B, Gulati M

Mini Rev Med Chem·2026·Animal·PubMed →

Advances in Fc-based Biotherapeutics: Fusion Proteins, Engineering, and Emerging Conjugation Strategies.

Gravino ME, Doyle RP

Mini Rev Med Chem·2026·Animal·PubMed →

Emerging Role of Natural Products and Dietary Supplements in Major Depressive Disorder: Therapeutic and Mechanistic Insights.

Yadav AK, Sah BK, Ahmad F et al.

Mini Rev Med Chem·2026·Animal·PubMed →

Chlorogenic Acid Attenuates Liver Fibrosis in Mice via HIF-1α Inhibition and M2 Macrophage Polarization.

Zhang Y, Feng L, Tang T et al.

Curr Med Chem·2026·Animal·PubMed →

GRF1 fine-tunes the copper-responsive transcription module of CPK3-bHLH107 by manipulating interaction and phosphorylation.

Yu Y, Xia H, Dong R et al.

Plant J·2026·Animal·PubMed →

SLC7A11 as a Prognostic Biomarker and Therapeutic Target in Renal Cell Carcinoma: Insights into Tumor Microenvironment Remodeling and Immune Infiltration.

Cheng X, Zhang J, Yuan J et al.

Curr Med Chem·2026·Animal·PubMed →

Natural Products in the Prevention and Treatment of Skin Photoaging: A Review of Mechanisms, Challenges, and Future Perspectives.

Fang Y, Chen Y, Chang L et al.

Mini Rev Med Chem·2026·Animal·PubMed →

Anti-Inflammatory Mechanism, Disease Treatment, and Application Prospects of Aloe-Emodin.

Wu J, Liu Y, He Y et al.

Mini Rev Med Chem·2026·Animal·PubMed →

Synergistic Effects of Herbal Bioactive Compounds and Growth Factors on Osteogenic Differentiation of Dental Derived Mesenchymal Stem Cells.

Khezri K, Hatamian-Zarmi A, Hoseinzadeh BE et al.

Curr Stem Cell Res Ther·2026·Animal·PubMed →

Interleukin-4 Supplementation During In Vitro Culture Modulates the Expression of Stress- and Immune-Related Genes During Porcine Blastocyst Development.

Garcia-Canovas M, Torregrosa-Fuentes M, Lopez-Jara A et al.

Reprod Domest Anim·2026·Animal·PubMed →

Decoding the lncRNA landscape in bovine mastitis: insights into immune regulation and gene networks underlying host response.

Bisutti V, Giannuzzi D, Vanzin A et al.

J Anim Sci Biotechnol·2026·Animal·PubMed →

Ursodeoxycholic acid enhances cancer radioimmunotherapy by releasing a human-biased FXR-TRIM22-STAT1 immune brake.

Li X, Jiang P, Yin H et al.

Cell Res·2026·Animal·PubMed →

GPCR antagonism via rewiring of receptor trafficking and degradation.

Rhee K, Shue L, Adachi A et al.

Nature·2026·Animal·PubMed →

MtvS1 and MtvS2 Interact with RNA polymerase to regulate the Francisella type V-A CRISPR-Cas system.

Brodmann M, Baca CF, Chandanani J et al.

Nat Commun·2026·Animal·PubMed →

A dual-host regulatory hub integrating biofilm formation and innate immunity resistance.

Baillez A, Dewitte A, Pierre F et al.

Nat Commun·2026·Animal·Immune Modulation, Antimicrobial·PubMed →

IFN-γ-driven iNOS induction in macrophages mediates CAR T cell resistance in B cell lymphoma.

Lee SB, Pavy A, Beatty N et al.

Nat Commun·2026·Animal·Immune Modulation·PubMed →

Construction of IL-2 Sustained-Release Polysaccharide Hydrogel and Amelioration of Sjögren's Syndrome in a Murine Model.

Ni X, Jin X, Jin Y et al.

Eur J Pharm Sci·2026·Animal·PubMed →

Dietary nucleotide supplementation attenuates disease severity and modulates clinicopathological responses in lambs with neonatal diarrhea syndrome.

Pazarakioti T, Athanasiou LV, Ceron JJ et al.

Vet J·2026·Animal·PubMed →

Central infusion of prostaglandin E2 reveals a unified representation of sickness in the mouse insular cortex.

Kamm GB, Boffi JC, Abd El Hay MY et al.

Curr Biol·2026·Animal·PubMed →

Salicylic acid engages central metabolic regulators SnRK1 and TOR to govern immunity by differential phosphorylation of NPR1.

Chen Y, Withers J, Sun Y et al.

Cell·2026·Animal·PubMed →

NLRP3 inflammasome activation and impaired Treg-mediated immune tolerance are associated with spontaneous preterm birth: A case-control study with in vitro probiotic metabolite intervention.

Wang X, Zhuang L, Huang H et al.

J Reprod Immunol·2026·Animal·PubMed →

Urban parks as potential hotspots for pathogenic determinants: A One Health perspective on environmental-human transmission risks.

Mu X, Bi J, Yu Q et al.

J Environ Manage·2026·Animal·PubMed →

Dose dependent immune and antioxidant in responses to low dose radiation.

Yousif AE, Abdelgawad MH, Kamal KA et al.

Appl Radiat Isot·2026·Animal·PubMed →

c-MET/NF-κB axis modulates PD-L1 and CCL22-mediated immune evasion and its inhibition enhances anti-PD-1 efficacy in non-small cell lung cancer.

Chen L, Yao X, Su C et al.

Int Immunopharmacol·2026·Animal·PubMed →

Chemo-metallo nanodrivers for spatiotemporally controlled in situ vaccination.

Li X, Lei H, Chen Y et al.

Sci Adv·2026·Animal·PubMed →

Hyperosmotic niche adaptation and tissue polyamines underlie MRSA persistence in the kidney.

Kanazawa N, Martens CP, Makino S et al.

Sci Transl Med·2026·Animal·PubMed →

Impact of Oral Cladribine on TSPO-PET-Measurable Immune Cell Activation in Multiple Sclerosis.

Rajalehto O, Matilainen M, Lehto J et al.

Neurol Ther·2026·Animal·PubMed →

DNA/RNA Heteroduplex Oligonucleotide for Highly Efficient Gene Silencing.

Hara RI, Yoshioka K

Methods Mol Biol·2026·Animal·PubMed →

Caspofungin-induced β-(1,3)-glucan unmasking is associated with enhanced innate immune clearance of Candida (Candidozyma) auris.

Kamasah JS, Akin BE, Baker LJ et al.

Microbiol Spectr·2026·Animal·PubMed →

C. elegans dauer morphogenesis requires inhibition of DBL-1/BMP signaling by ztf-30.

Godoy LF, Páez ME, Salvatore NR et al.

Development·2026·Animal·PubMed →

Advances in the Inflammatory and Immune-mediated Kidney Disorders (IMKD): From Pathogenesis to Precision Therapy.

Singh SR, Patel AK, Kumar D et al.

Recent Adv Inflamm Allergy Drug Discov·2026·Animal·PubMed →

Bioinformatics Analysis of T-cell Exhaustion Genes in Pediatric Allergic Rhinitis and their Clinical Diagnostic Significance.

Niu H, Chai X, Wang Q

Endocr Metab Immune Disord Drug Targets·2026·Animal·PubMed →

4-Methylumbelliferone Restores Age-Related Changes in Perineuronal Nets, Memory, and Neuroinflammation.

Cimpean A, Mizerakova J, Martinez-Varea N et al.

Glia·2026·Animal·Longevity, Tissue Remodeling, Cognitive Enhancement·PubMed →

Complement Proteins C1q-C5 as Context‑Dependent Regulators of Osteoblast Function and Fracture Healing: A Systematic Review.

Counts PR, Baer TM, Viswanath O et al.

Orthop Rev (Pavia)·2026·Animal·PubMed →

Sequential exposure to histological chorioamnionitis and postnatal hyperoxia alters gene expression in cord blood monocytes.

Sequeira Gomes R, Gayen Nee' Betal S, Addya S et al.

Front Pediatr·2026·Animal·PubMed →

Discovery of plasma metabolomic biomarkers and a predictive model for immune checkpoint inhibitor-associated myocarditis: a pilot case-control study.

Zheng Z, Gu Q, Wang Y et al.

Front Immunol·2026·Animal·PubMed →

CX3CL1-CX3CR1 axis promotes restraint stress-induced thymic involution through macrophage-mediated thymocyte apoptosis.

Ishida Y, Kuninaka Y, Nosaka M et al.

Front Immunol·2026·Animal·Immune Modulation·PubMed →

Cancer stem cell programs S-nitrosylation and deubiquitination of FoxP3 protein to promote regulatory T cell differentiation.

Liu X, Lei J, Jiang X et al.

Front Immunol·2026·Animal·PubMed →

Ketogenic diet fails to mitigate seizures and neuroinflammatory responses in a mouse model of virus-induced epilepsy.

Meili CH, Allen K, Doty DJ et al.

Epilepsia·2026·Animal·PubMed →

The future of cancer therapy? Integrating oncolytic adenoviruses with epigetic modulation.

Zulfiqar S, Wang X, Chen B et al.

Epigenomics·2026·Animal·PubMed →

Engineering a Built-in Piezoelectric Electron Sponge in Swallow Nanozyme for Inflammatory Bowel Disease Therapy.

Jiang Z, Yue Z, Zhao Q et al.

Small·2026·Animal·PubMed →

Androgens Modulate Tumor-Immune Interactions in Testicular Germ Cell Tumors.

Hamann I, Klaus L, Fruth P et al.

Andrology·2026·Animal·PubMed →