Research Index

Setmelanotide Research Index

PSI surfaces 50 peer-reviewed studies on Setmelanotide, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.

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50 studies

Case Report: Pseudomonas liver abscess in a previously healthy child with homozygous pathogenic S allele variant of the SERPINA1 gene.

Thomas S, D'Souza AW, Alhezam M et al.

Front Immunol·2026·Human·PubMed →

Genomic characterization of Comamonas kerstersii isolated from diarrheal patients in Bangladesh.

Rib NI, Shams F, Khan F et al.

PLoS One·2026·Human·PubMed →

Postoperative complications in patients with chemotherapy-induced acute myeloid leukemia (Review).

Lin CH, Liu HT, Hsieh CH

Oncol Lett·2026·Human·PubMed →

Comparative RNA sequencing analysis of resistant and susceptible Dendrobium "Earsakul" under black rot challenge.

Tantasawat PA, Inthaisong S, Chantakot T et al.

BioTechnologia (Pozn)·2026·Animal·PubMed →

Human respiratory syncytial virus regulates the expression of interferon-stimulated genes through modulation of fibrillarin.

Ulloa-Aguilar JM, Cruz-Holguin VJ, Benítez-Zeferino YR et al.

Front Cell Infect Microbiol·2026·Animal·PubMed →

Protective role of mucosa-associated invariant T cells in sepsis-related liver injury.

Bu W, Ji Q, Yao Y et al.

Front Immunol·2026·Animal·Liver Protection, Anti-Inflammatory·PubMed →

cJun-assisted loading of RelA DNA-binding promotes synergistic lung epithelial antimicrobial responses.

Pantaleón García J, Bhoda K, Burch-Eapen M et al.

iScience·2026·Animal·PubMed →

Immune-mediated microbial interference governs Borrelia colonization of the tick gut.

Hodžić A, Kunert M, Juračić M et al.

iScience·2026·Animal·PubMed →

Nested mobile genetic elements mediating antimicrobial resistance genes mobility within and between Acinetobacter isolates.

Bongulto K, Kagia N, Tauchi H et al.

iScience·2026·Animal·PubMed →

Disaggregation of Colletotrichum truncatum by Peppermint Oil Nanoemulsion during Anthracnose Disease in Glycine max.

Kumar N, Tripathi A, Chauhan P et al.

Curr Microbiol·2026·Animal·PubMed →

BRD4 modulates antimicrobial defense via non-canonical NRF2 activation in macrophages to confer protection against sepsis.

Hu J, Gao X, Li G et al.

PLoS Pathog·2026·Animal·PubMed →

Co-occurrence of the tigecycline resistance gene cluster tmexCD3-toprJ1 and verona integron-encoded metallo-β-lactamase (VIM) in a human-derived Pseudomonas sediminis isolate.

Shen H, Chen A, Cai C et al.

Microbiol Spectr·2026·Animal·PubMed →

Bioactive Amino-Carbon Dots for Sustainable Crop Protection: Cellular Uptake and Metabolomic Insights into the Antifungal and Antibacterial Activity in Tomato Plants.

Camilli A, Patriarca A, Ferrante P et al.

ACS Appl Mater Interfaces·2026·Animal·PubMed →

Editorial: ESKAPEing host endogenous and exogenous defenses: new insights into the ability of multidrug- resistant bacteria to overcome host defenses and antimicrobial compounds activity.

Ascenzioni F, Cavinato L, Alva-Murillo N

Front Cell Infect Microbiol·2026·Animal·PubMed →

Activity Identification and Proteomics Analysis of Water-Soluble Proteins in Cocoon Coat from Different Silkworm Varieties.

Tian H, Chen W, Li J et al.

Insect Biochem Mol Biol·2026·Animal·PubMed →

Transcriptome analysis revealed immune protection conferred by bath vaccination with formalin-killed Vibrio parahaemolyticus on Penaeus vannamei.

Angela Bermeo-Capunong MR, Matthew Domingo Guzman JP, Langote Alolod GA et al.

Fish Shellfish Immunol·2026·Animal·PubMed →

Investigation of L-Phe induced biocontrol efficiency of Yarrowia lipolytica against postharvest blue mold of pears and its underlying mechanisms.

Zhao L, Qiu C, He Y et al.

Int J Food Microbiol·2026·Animal·PubMed →

Neurotrophic and metabolic consequences of virgin coconut oil and ethanol: implications for growth and antioxidant defense.

Asrar B, Haleem DJ, Khan A et al.

Mol Biol Rep·2026·Animal·PubMed →

Unlocking the secret to Staphylococcus aureus survival in serum.

Rose WE, Sauer J-D

mSystems·2026·Animal·PubMed →

Assessment of the Prioritization of Diagnostics in National Action Plans for Antimicrobial Resistance.

Lamb G, Pallett SJC, Charani E et al.

Clin Infect Dis·2026·Animal·PubMed →

'Candidatus Liberibacter asiaticus' Effector SDE4250 Targets Citrus Proteasome Protein RPN10 to Inhibit Salicylic Acid-Mediated Citrus Immunity.

Mei Y, Deng X, Yang Z et al.

Mol Plant Pathol·2026·Animal·PubMed →

Melatonin enhances drought tolerance in lemongrass: physiological, biochemical, and antioxidant mechanisms.

Nazarideljou MJ, Lahijani K, Farabi S et al.

Sci Rep·2026·Animal·PubMed →

Retinoic Acid-inducible Gene-I Increases Interferon-stimulated Gene 15 Expression in Human Renal Proximal Tubule Epithelial Cells.

Tachizaki M, Kawaguchi S, Tanaka H et al.

In Vivo·2026·Animal·Anti-Inflammatory, Immune Modulation·PubMed →

Freezing Nitrogen-Ethanol Composite Effectively Eradicates Staphylococcus aureus Biofilm on Prosthetic Surfaces.

Lin YK, Lee KH, Chen CM et al.

In Vivo·2026·Animal·Antimicrobial·PubMed →

Structure of the hibernating Francisella tularensis ribosome and mechanistic insights into its inhibition by antibiotics.

Klima M, Silhan J, Pavlik P et al.

Nucleic Acids Res·2026·Animal·Antimicrobial·PubMed →

Influence of a garlic-based additive on the performance parameters and intestinal morphology of replacement gilts in Ukraine under commercial conditions.

Lykhach V, Bevz N, Lykhach A et al.

Vet World·2026·Animal·PubMed →

The bZIP Transcription Factor PjbZIP1 Enhances Resistance to Powdery Mildew in Paeonia jishanensis by Directly Activating PjICS Involved in the SA Pathway.

Zhao XC, Li M, Niu JY et al.

Physiol Plant·2026·Animal·PubMed →

Caffeic Acid Phenethyl Ester Enhanced the Klotho/SIRT1/Nrf2/HO-1 Axis to Protect Against Methylmercury-Induced ALS-Like Neurodegeneration.

Rana R, Mehan S, Mukherjee R et al.

Mol Neurobiol·2026·Animal·Neuroprotection·PubMed →

Exploring the immunological functions of calreticulin 3a from Scomber japonicus (SjCalr3a): insight into antimicrobial defense, cytoprotection, and pro-inflammatory responses.

Rodrigo DCG, Kodagoda YK, Dilshan MAH et al.

Fish Shellfish Immunol·2026·Animal·PubMed →

Neomycin Exhibits Immunomodulatory and Antiviral Activity Against Influenza B Virus.

Romanovskaya-Romanko E, Plotnikova M, Shurygina AP et al.

Viruses·2026·Animal·Anti-Inflammatory·PubMed →

LL-37 Inhibits EV71 Infection by Upregulating STAC via the EGFR-ERK Signaling Pathway.

Zhang J, Zhang H, Chen Y et al.

Viruses·2026·Animal·PubMed →

EMCV Non-Structural Protein 2C Antagonizes cGAS-STING-Mediated Type I Interferon Signaling via Promoting K48-Linked Polyubiquitination and Degradation of STING.

Cheng R, Dong P, Xing W et al.

Viruses·2026·Animal·Immune Modulation·PubMed →

Characterization of Klebsiella Phages Isolated Against a Clinical Host with High Genome and Proteome Identity but Variable Tail Fibers.

Lewis JM, Arens DK, Zuniga NR et al.

Viruses·2026·Animal·PubMed →

Biocontrol Potential and Functional Characteristics of Bacillus sonorensis A-5 Against Watermelon Fusarium Wilt.

Jiang JW, Qiu Y, Ye LT et al.

J Fungi (Basel)·2026·Animal·PubMed →

Virulence Phenotypes Differentiate Persistent vs. Resolving Isolates of Human Staphylococcus aureus Bacteremia.

Chan LC, Lee HK, Wang L et al.

Antibiotics (Basel)·2026·Animal·PubMed →

Exploring the molecular crosstalk between the sex steroids drospirenone and ethinylestradiol with vaginal lactobacilli.

Muscò A, Tarracchini C, Rizzo SM et al.

Front Microbiol·2026·Animal·PubMed →

A novel GntR-ABC efflux system mediates oxidative stress response, drug resistance, motility and virulence in Acinetobacter baumannii ATCC 17978.

Corral J, Pérez-Varela M, Sánchez-Osuna M et al.

Front Microbiol·2026·Animal·PubMed →

Ancient DNA reveals that natural selection has upregulated the immune system over the last 10,000 years.

Maravall-López J, Truong B, Kerner G et al.

bioRxiv·2026·Animal·PubMed →

Impact of allyl-isothiocyanate and high sucrose diet on antimicrobial peptide expression and survival in Drosophila melanogaster.

Dähn S, Zimmermann C, Merschmann R et al.

Front Immunol·2026·Animal·Antimicrobial·PubMed →

Dual-defense functionality of temporin-1LS from dark-spotted frogs (Pelophylax nigromaculatus): antimicrobial activity and immunomodulatory effects via macrophage activation.

Ma L, Wu S, Hu H et al.

Front Immunol·2026·Animal·Antimicrobial·PubMed →

Carvacrol as a one health-relevant antimicrobial agent: mechanistic insights on its impact on gnotobiotic Artemia and Vibrio campbellii interactions.

Baruah K, Debnath D, Patabandi PPSK et al.

Front Immunol·2026·Animal·Antimicrobial·PubMed →

d-Galactose-conjugated pyrimidine thioureas as potent antimicrobial agents: rapid green synthesis, structure-activity relationships and molecular modelling.

Thanh ND, Toan VN, Thu NHA et al.

RSC Med Chem·2026·Animal·PubMed →

Genomic and functional approaches point to potential determinants of neonatal K. pneumoniae sepsis.

Rout M, Rani K, Mahanta J et al.

Microbiol Spectr·2026·Animal·PubMed →

Draft genome assemblies of doxycycline-resistant derivatives of Bacillus cereus strain ATCC14579.

Harrison S, Ernlund A, Verratti K et al.

Microbiol Resour Announc·2026·Animal·PubMed →

Linking oxidative stress defense to biofilm architecture: Ohr mediates strain-dependent persistence in Acinetobacter baumannii.

Yu R, Al-Shamiri MM, Zhang S et al.

Virulence·2026·Animal·Antimicrobial·PubMed →

Simulated heat waves aggravate the immune response to sublethal acetamiprid exposure in the honey bee (Apis mellifera).

Jerele L, Urva P, Bednář A et al.

Pestic Biochem Physiol·2026·Animal·Antimicrobial·PubMed →

Melatonin-dobed nano‑selenium treatment of potato plant induces direct resistance against Spodoptera litura and indirectly reshapes volatile mediated biological interactions.

Munawar A, Yao J, El-Ela AA et al.

Pestic Biochem Physiol·2026·Animal·PubMed →

Multifunctional MoS₂/PDA@Cu nano-composites suppress tobacco bacterial wilt via enhanced antimicrobial activity, induced resistance, and growth promotion.

Xie M, Qian K, Yang J et al.

Pestic Biochem Physiol·2026·Animal·Antimicrobial·PubMed →

Identification and Functional Characterization of Tenebrio molitor Inhibitor of Apoptosis Protein 2 (TmIAP2) in the Innate Immune Response.

Yun K, Vasantha-Srinivasan P, Hwang SH et al.

Dev Comp Immunol·2026·Animal·PubMed →

Small regulatory RNAs modulate lactococcal susceptibility to cell wall-targeting antimicrobials.

Mickutė M, Kvederavičiūtė K, Ličytė J et al.

Nucleic Acids Res·2026·Animal·Antimicrobial·PubMed →