Research Index

Selank Research Index

PSI surfaces 50 peer-reviewed studies on Selank, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.

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50 studies

Benefits of alanyl-glutamine and omega-3 PUDAs in postoperative gastroduodenal perforation patients: A single-center retrospective study.

Liu X, Mao W, Zhao G et al.

Medicine (Baltimore)·2025·Human·PubMed →

Hepatoprotective Effects of Thymogen Analogues in Hydrazine Hepatopathy in Rats.

Chulanova AA, Smakhtina AM, Mal GS et al.

Bull Exp Biol Med·2025·Animal·Liver Protection·PubMed →

Taste characterization and molecular docking study of novel umami flavor peptides in Yanjin black bone Chicken meat.

Yang C, Ge X, Ge C et al.

Food Chem·2025·Animal·PubMed →

Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats.

Konstantinopolsky MA, Chernyakova IV, Kolik LG

Bull Exp Biol Med·2022·Animal·PubMed →

Improving the nutritional value and bioactivity of soybean meal in solid-state fermentation using Bacillus strains newly isolated from the gut of the termite Termes propinquus.

Nualkul M, Yuangsoi B, Hongoh Y et al.

FEMS Microbiol Lett·2022·Animal·PubMed →

Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank.

Doyno CR, White CM

J Clin Pharmacol·2021·Animal·PubMed →

The Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress.

Leonidovna YA, Aleksandrovna SM, Aleksandrovna TA et al.

Curr Rev Clin Exp Pharmacol·2021·Animal·Anti-Inflammatory, Anxiety & Mood·PubMed →

Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank.

Mukhina AY, Mishina ES, Bobyntsev II et al.

Bull Exp Biol Med·2020·Animal·PubMed →

Functional Connectomic Approach to Studying Selank and Semax Effects.

Panikratova YR, Lebedeva IS, Sokolov OY et al.

Dokl Biol Sci·2020·Animal·PubMed →

The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations: An incentive for controlling agencies to prepare for future encounters of the kind.

Vanhee C, Francotte A, Janvier S et al.

Drug Test Anal·2020·Animal·PubMed →

Effects of Huatan Tongluo decoction on vascular endothelial growth factor receptor 2 expression in synovial tissues of rats with collagen-induced arthritis.

Chen J, Qiu M, Li Y et al.

J Tradit Chin Med·2019·Animal·PubMed →

Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats.

Kolik LG, Nadorova AV, Antipova TA et al.

Bull Exp Biol Med·2019·Animal·PubMed →

Effect of Selank on Morphological Parameters of Rat Liver in Chronic Foot-Shock Stress.

Fomenko EV, Bobyntsev II, Ivanov AV et al.

Bull Exp Biol Med·2019·Animal·Liver Protection·PubMed →

State of Colon Microbiota in Rats during Chronic Restraint Stress and Selank Treatment.

Mukhina AY, Medvedeva OA, Svishcheva MV et al.

Bull Exp Biol Med·2019·Animal·PubMed →

Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity.

Vyunova TV, Andreeva L, Shevchenko K et al.

Protein Pept Lett·2018·Animal·PubMed →

Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed by Thromboelastography.

Rogozinskaya EY, Lyapina MG

Bull Exp Biol Med·2017·Animal·PubMed →

Studying the Toxic Effects of Some Biologically Active Peptides on the Model of Mouse Embryonic Stem Cells.

Kobylyanskii AG, Zolotarev YA, Andreeva LA et al.

Bull Exp Biol Med·2017·Animal·Neuroprotection·PubMed →

Effect of Selank on Functional State of Rat Hepatocytes under Conditions of Restraint Stress.

Fomenko EV, Bobyntsev II, Kryukov AA et al.

Bull Exp Biol Med·2017·Animal·Liver Protection·PubMed →

Peptides semax and selank affect the behavior of rats with 6-OHDA induced PD-like parkinsonism.

Slominsky PA, Shadrina MI, Kolomin TA et al.

Dokl Biol Sci·2017·Animal·Anxiety & Mood·PubMed →

Effect of Selank on Spontaneous Synaptic Activity of Rat Hippocampal CA1 Neurons.

Povarov IS, Kondratenko RV, Derevyagin VI et al.

Bull Exp Biol Med·2017·Animal·Neuroprotection·PubMed →

GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells.

Filatova E, Kasian A, Kolomin T et al.

Front Pharmacol·2017·Animal·PubMed →

Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats.

Kasian A, Kolomin T, Andreeva L et al.

Behav Neurol·2017·Animal·Anxiety & Mood·PubMed →

A Novel Peptide Derived From Tissue-Type Plasminogen Activator Potently Inhibits Angiogenesis and Corneal Neovascularization.

Kim HK, Choi JS, Lee SW et al.

J Cell Biochem·2017·Animal·PubMed →

Selank Inhibits Ethanol-Induced Hyperlocomotion and Manifestation of Behavioral Sensitization in DBA/2 Mice.

Kolik LG, Nadorova AV, Seredenin SB

Bull Exp Biol Med·2016·Animal·PubMed →

Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission.

Volkova A, Shadrina M, Kolomin T et al.

Front Pharmacol·2016·Animal·PubMed →

[COMPARISON OF PHARMACOLOGICAL EFFECTS OF HEPTAPEPTIDE SELANK AFTER INTRANASAL AND INTRAPERITONEAL ADMINISTRATION TO BALB/c AND C57BL/6 MICE.].

Vasil'eva EV, Kondrakhin EA, Salimov RM et al.

Eksp Klin Farmakol·2016·Animal·PubMed →

[Optimization of the treatment of anxiety disorders with selank].

Medvedev VE, Tereshchenko ON, Kost NV et al.

Zh Nevrol Psikhiatr Im S S Korsakova·2015·Human·PubMed →

[A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders].

Medvedev VE, Tereshchenko ON, Israelian AIu et al.

Zh Nevrol Psikhiatr Im S S Korsakova·2014·Human·PubMed →

[Effect of tripeptide Pro-Gly-Pro on rat brain transcriptome in focal ischemia].

Medvedeva EV, Dmitrieva VG, Povarova OV et al.

Mol Biol (Mosk)·2014·Animal·Anti-Inflammatory, Immune Modulation, Neuroprotection·PubMed →

The influence of Selank on the parameters of the hemostasis system, lipid profile, and blood sugar level in the course of experimental metabolic syndrome.

Mjasoedov NF, Andreeva LA, Grigorjeva ME et al.

Dokl Biol Sci·2014·Animal·Glycemic Control, Metabolic Syndrome·PubMed →

Efficacy of peptide anxiolytic selank during modeling of withdrawal syndrome in rats with stable alcoholic motivation.

Kolik LG, Nadorova AV, Kozlovskaya MM

Bull Exp Biol Med·2014·Animal·Anxiety & Mood·PubMed →

The temporary dynamics of inflammation-related genes expression under tuftsin analog Selank action.

Kolomin T, Morozova M, Volkova A et al.

Mol Immunol·2014·Animal·Anti-Inflammatory·PubMed →

[Transcriptome alteration in hippocampus under the treatment of tuftsin analog Selank].

Kolomin TA, Agapova TIu, Agniullin IaV et al.

Zh Vyssh Nerv Deiat Im I P Pavlova·2013·Animal·PubMed →

The influence of oligopeptides on spontaneous carcinogenesis in mice.

Meshavkin VK, Kost NV, Sokolov OY et al.

Dokl Biol Sci·2013·Animal·Weight Loss·PubMed →

[Protective effect of selank on the model of mnestic function violation induced by pharmacological blockade of protein synthesis].

Kozlovskiĭ II, Belozertsev FIu, Andreeva LA et al.

Eksp Klin Farmakol·2013·Animal·PubMed →

Natriuretic peptides for the detection of paroxysmal atrial fibrillation in patients with cerebral ischemia--the Find-AF study.

Wachter R, Lahno R, Haase B et al.

PLoS One·2012·Human·PubMed →

[Effect of selank on the main carboxypeptidases in the rat nervous tissue].

Solov'ev VB, Gengin MT, Sollertinskaia TN et al.

Zh Evol Biokhim Fiziol·2012·Animal·PubMed →

[The role of opioid system in peculiarities of anti-anxiety effect of peptide anxiolytic selank].

Kozlovskiĭ II, Andreeva LA, Kozlovskaia MM et al.

Eksp Klin Farmakol·2012·Animal·Anxiety & Mood, Neuroprotection·PubMed →

[Peptidergic modulation of the hippocampus synaptic activity].

Skrebitskiĭ VG, Kondratenko RV, Povarov IS et al.

Ross Fiziol Zh Im I M Sechenova·2011·Animal·PubMed →

[Changes in expression of the genes for chemokines, cytokines, and their receptors in response to selank and its fragments].

Kolomin TA, Shadrina MI, Slominskiĭ PA et al.

Genetika·2011·Animal·Anti-Inflammatory·PubMed →

Expression of inflammation-related genes in mouse spleen under tuftsin analog Selank.

Kolomin T, Shadrina M, Andreeva L et al.

Regul Pept·2011·Animal·Anti-Inflammatory·PubMed →

Ex vivo screening of prospective peptide drugs: new approaches.

Andreeva LA, Mezentseva MV, Nagaev IY et al.

Dokl Biol Sci·2010·Animal·Anti-Inflammatory·PubMed →

[Experimental optimization of learning and memory processes by selank].

Semenova TP, Kozlovskiĭ II, Zakharova NM et al.

Eksp Klin Farmakol·2010·Animal·Cognitive Enhancement, Neuroprotection·PubMed →

Antiviral properties of structural fragments of the peptide Selank.

Andreeva LA, Nagaev IY, Mezentseva MV et al.

Dokl Biol Sci·2010·Animal·PubMed →

Transcriptomic response of rat hippocampus and spleen cells to single and chronic administration of the peptide selank.

Kolomin TA, Shadrina MI, Agniullin YV et al.

Dokl Biochem Biophys·2010·Animal·PubMed →

[Antiviral activity of immunomodulator Selank in experimental influenza infection].

Ershov FI, Uchakin PN, Uchakina ON et al.

Vopr Virusol·2009·Animal·Anti-Inflammatory·PubMed →

[Comparison of the effects of selank and tuftsin on the metabolism of serotonin in the brain of rats pretreated with PCPA].

Semenova TP, kozlovskiĭ II, Zakharova NM et al.

Eksp Klin Farmakol·2009·Animal·Neuroprotection·PubMed →

[Experimental hemorrhagic stroke: the study of neuropeptides (MIF, selank) in the intraperitoneal injection].

Skvortsova VI, Tvorogova TV, Dubina AI et al.

Zh Nevrol Psikhiatr Im S S Korsakova·2009·Animal·Weight Loss·PubMed →

[Immunomodulatory effects of selank in patients with anxiety-asthenic disorders].

Uchakina ON, Uchakin PN, Miasoedov NF et al.

Zh Nevrol Psikhiatr Im S S Korsakova·2008·Human·Anxiety & Mood, Immune Modulation·PubMed →

[Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia].

Zozulia AA, Neznamov GG, Siuniakov TS et al.

Zh Nevrol Psikhiatr Im S S Korsakova·2008·Human·PubMed →