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INDEXED STUDIES

PT-141 (Bremelanotide) — Indexed Studies

50 most recent studies indexed by PSI from PubMed and clinical databases

Showing 50 of 50 studies

Practical considerations and emerging approaches for the management of vasomotor and sexual symptoms in breast cancer patients on endocrine therapies.

Fuhrman J, Yun J, Indorf A

Expert Rev Clin Pharmacol(2025)
Human
Sexual Health
PubMed

Gap in Sexual Dysfunction Management Between Male and Female Patients Seen in Primary Care: An Observational Study.

Stanley EE, Pfoh E, Lipold L et al.

J Gen Intern Med(2025)
Human
Sexual Health
PubMed

First-time orgasm in a young man with lifelong anorgasmia after flibanserin use: a case report.

Saffati G, Naeem T, Kaaki B et al.

Sex Med(2023)
Human
PubMed

Expression of Concern: Salvage of Sildenafil Failures With Bremelanotide: A Randomized, Double-Blind, Placebo Controlled Study.

Safarinejad MR, Hosseini SY

J Urol(2023)
Human
PubMed

Prespecified and Integrated Subgroup Analyses from the RECONNECT Phase 3 Studies of Bremelanotide.

Simon JA, Kingsberg SA, Portman D et al.

J Womens Health (Larchmt)(2022)
Human
Sexual Health
PubMed

Safety Profile of Bremelanotide Across the Clinical Development Program.

Clayton AH, Kingsberg SA, Portman D et al.

J Womens Health (Larchmt)(2022)
Human
Sexual Health
PubMed

Failure of a Meta-analysis: A Commentary on Glen Spielmans's "Re-Analyzing Phase III Bremelanotide Trials for 'Hypoactive Sexual Desire Disorder in Women'".

Kingsberg SA, Clayton AH, Portman D et al.

J Sex Res(2021)
Human
Sexual Health
PubMed

Re-Analyzing Phase III Bremelanotide Trials for "Hypoactive Sexual Desire Disorder" in Women.

Spielmans GI

J Sex Res(2021)
Human
PubMed

The Patient Experience of Premenopausal Women Treated with Bremelanotide for Hypoactive Sexual Desire Disorder: RECONNECT Exit Study Results.

Koochaki P, Revicki D, Wilson H et al.

J Womens Health (Larchmt)(2021)
Human
Sexual Health
PubMed

Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials.

Kingsberg SA, Clayton AH, Portman D et al.

Obstet Gynecol(2019)
Human
PubMed

Responder Analyses from a Phase 2b Dose-Ranging Study of Bremelanotide.

Althof S, Derogatis LR, Greenberg S et al.

J Sex Med(2019)
Human
Sexual Health
PubMed

Phase I Randomized Placebo-controlled, Double-blind Study of the Safety and Tolerability of Bremelanotide Coadministered With Ethanol in Healthy Male and Female Participants.

Clayton AH, Lucas J, DeRogatis LR et al.

Clin Ther(2017)
Human
PubMed

Usefulness of ambulatory blood pressure monitoring to assess the melanocortin receptor agonist bremelanotide.

White WB, Myers MG, Jordan R et al.

J Hypertens(2017)
Human
PubMed

Re: Bremelanotide for Female Sexual Dysfunctions in Premenopausal Women: A Randomized, Placebo-Controlled Dose-Finding Trial.

Seftel AD

J Urol(2016)
Human
PubMed

Bremelanotide for female sexual dysfunctions in premenopausal women: a randomized, placebo-controlled dose-finding trial.

Clayton AH, Althof SE, Kingsberg S et al.

Womens Health (Lond)(2016)
Human
PubMed

Hypoactive sexual desire disorder in women: treatment options beyond testosterone and approaches to communicating with patients on sexual health.

Lodise NM

Pharmacotherapy(2013)
Human
PubMed

Salvage of sildenafil failures with bremelanotide: a randomized, double-blind, placebo controlled study.

Safarinejad MR, Hosseini SY

J Urol(2008)
Human
PubMed

RETRACTED: Evaluation of the safety and efficacy of bremelanotide, a melanocortin receptor agonist, in female subjects with arousal disorder: a double-blind placebo-controlled, fixed dose, randomized study.

Safarinejad MR

J Sex Med(2008)
Human
Sexual Health
PubMed

An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide (PT-141), a melanocortin receptor agonist.

Diamond LE, Earle DC, Heiman JR et al.

J Sex Med(2006)
Human
Sexual Health
PubMed

Co-administration of low doses of intranasal PT-141, a melanocortin receptor agonist, and sildenafil to men with erectile dysfunction results in an enhanced erectile response.

Diamond LE, Earle DC, Garcia WD et al.

Urology(2005)
Human
Sexual Health
PubMed

Gateways to clinical trials.

Bayés M, Rabasseda X, Prous JR

Methods Find Exp Clin Pharmacol(2004)
Human
PubMed

Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra.

Rosen RC, Diamond LE, Earle DC et al.

Int J Impot Res(2004)
Human
Sexual Health
PubMed

Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients with mild-to-moderate erectile dysfunction.

Diamond LE, Earle DC, Rosen RC et al.

Int J Impot Res(2004)
Human
Sexual Health
PubMed

PT-141: a melanocortin agonist for the treatment of sexual dysfunction.

Molinoff PB, Shadiack AM, Earle D et al.

Ann N Y Acad Sci(2003)
Human
Sexual HealthNeuroprotection
PubMed

Strategies for Treating Sexual Health Concerns After Breast and Gynecologic Cancer.

Mihulka O, Curran M, Narasimhan RM et al.

J Minim Invasive Gynecol(2025)
Animal
PubMed

FDA-approved drugs as potential covalent inhibitors of key SARS-CoV-2 proteins: an in silico approach.

Serilmez M, Abuelrub A, Erol I et al.

Turk J Biol(2025)
Animal
PubMed

A biodegradable suction patch for sustainable transbuccal peptide delivery.

Krupke H, Zoratto N, Rabut L et al.

J Control Release(2025)
Animal
PubMed

Female Syrian hamster analyses of bremelanotide, a US FDA approved drug for the treatment of female hypoactive sexual desire disorder.

Borland JM, Kohut-Jackson AL, Peyla AC et al.

Neuropharmacology(2025)
Animal
PubMed

Melanocortin Receptor Agonist Bremelanotide Induces Cell Death and Growth Inhibition in Glioblastoma Cells via Suppression of Survivin Expression.

Suzuki S, Kitanaka C, Okada M

Anticancer Res(2024)
Animal
PubMed

Finding Our Way From the Bench to the Bedside: The Ethos, Logos, and Pathos of Biomedical Research.

Kim NN

Sex Med Rev(2022)
Animal
PubMed

Pharmacotherapy for female sexual dysfunctions (FSDs): what is on the market and where is this field heading?

Nappi RE, Tiranini L, Cucinella L et al.

Expert Opin Pharmacother(2023)
Animal
PubMed

Effect of bremelanotide on body weight of obese women: Data from two phase 1 randomized controlled trials.

Spana C, Jordan R, Fischkoff S

Diabetes Obes Metab(2022)
Animal
Weight Loss
PubMed

Psychometric validation of the Female Sexual Distress Scale-Desire/Arousal/Orgasm.

Derogatis LR, Revicki DA, Rosen RC et al.

J Patient Rep Outcomes(2021)
Animal
PubMed

Structural insights into ligand recognition and activation of the melanocortin-4 receptor.

Zhang H, Chen LN, Yang D et al.

Cell Res(2021)
Animal
PubMed

LC-HRMS characterization of the skin pigmentation and sexual enhancers melanotan II and bremelanotide sold on the black market of performance and image enhancing drugs.

Mestria S, Odoardi S, Frison G et al.

Drug Test Anal(2021)
Animal
PubMed

Reliability and validity of the elements of desire questionnaire in premenopausal women with hypoactive sexual desire disorder.

Revicki DA, Althof SE, Derogatis LR et al.

J Patient Rep Outcomes(2020)
Animal
PubMed

Female Hypoactive Sexual Desire Disorder: A Practical Guide to Causes, Clinical Diagnosis, and Treatment.

Kingsberg SA, Simon JA

J Womens Health (Larchmt)(2020)
Animal
Sexual Health
PubMed

Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics.

Sauter M, Uhl P, Burhenne J et al.

J Pharm Biomed Anal(2020)
Animal
PubMed

New Drugs 2020, part 2.

Hussar DA

Nursing(2020)
Animal
PubMed

Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder.

Simon JA, Kingsberg SA, Portman D et al.

Obstet Gynecol(2019)
Animal
PubMed

Boosting Female Sexual Response by RECONNECTing the Dots.

Carson SA

Obstet Gynecol(2019)
Animal
Sexual Health
PubMed

New Drug for Hypoactive Sexual Desire Disorder in Premenopausal Women.

Aschenbrenner DS

Am J Nurs(2019)
Animal
Sexual Health
PubMed

What are the challenges in prescribing pharmacotherapy for female sexual dysfunctions?

Nappi RE, Gardella B

Expert Opin Pharmacother(2019)
Animal
PubMed

Sexual arousal: Sex matters.

Petherick A

Nature(2017)
Animal
NeuroprotectionSexual Health
PubMed

[2013 annual meeting of the International Society for the Study of Women's Sexual Health (ISSWSH), 28 February-3 March 2013, New Orleans, Louisiana, USA. State of pharmacologial research in Women's Sexual Medicine: From testosterone to bremelatonide].

Buvat J

Gynecol Obstet Fertil(2013)
Animal
PubMed

Melanotan II injection resulting in systemic toxicity and rhabdomyolysis.

Nelson ME, Bryant SM, Aks SE

Clin Toxicol (Phila)(2012)
Animal
PubMed

Gateways to clinical trials.

Tomillero A, Moral MA

Methods Find Exp Clin Pharmacol(2008)
Animal
PubMed

Gateways to clinical trials.

Tomillero A, Moral MA

Methods Find Exp Clin Pharmacol(2008)
Animal
PubMed

Pharmacological profiling of neuropeptides on rabbit vaginal wall and vaginal artery smooth muscle in vitro.

Aughton KL, Hamilton-Smith K, Gupta J et al.

Br J Pharmacol(2008)
Animal
PubMed

Gateways to clinical trials.

Bayes M, Rabasseda X, Prous JR

Methods Find Exp Clin Pharmacol(2007)
Animal
PubMed
Back to PT-141 (Bremelanotide) Research Overview

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