Research Index
p28 (Azurin Peptide Fragment) Research Index
PSI surfaces 50 peer-reviewed studies on p28 (Azurin Peptide Fragment), prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
50 studies
Growth Hormone-Releasing Peptide-6 (GHRP-6) Ameliorates Post-Infarct Ventricular Remodeling and Systolic Dysfunction in a Model of Permanent Coronary Ligation.
Wang L, Rodriguez-Ulloa A, Berlanga-Acosta J et al.
Pharmaceuticals (Basel)·2026·Animal·PubMed →
Growth hormone releasing peptide-6 (GHRP-6) ameliorates acute lung injury and its subsequent evolvement to interstitial fibrosis.
Wang L, Berlanga-Acosta J, Yu H et al.
Int Immunopharmacol·2026·Animal·PubMed →
Oral salmon acylated ghrelin increases food intake in common carp (Cyprinus carpio) via ghrelin receptors, likely through sensory nerves rather than systemic absorption.
Kihara M, Yamagiwa T, Katayama H et al.
Peptides·2026·Animal·PubMed →
Effect of intracerebroventricular (ICV) injection of antimicrobial peptide expressed in the body-2 (LEAP-2) and its interaction with cannabinoid and ghrelin systems on food intake in broiler chickens.
Rahmania A, Zendehdel M, Hassanpour S
Poult Sci·2026·Animal·Antimicrobial·PubMed →
Growth hormone-releasing peptide 6 (GHRP-6) hydrogel for acute kidney injury therapy via metabolic regulation.
Zhao X, Pan K, Li R et al.
J Nanobiotechnology·2025·Animal·PubMed →
Aza-Isotryptophan: Synthesis, Pictet-Spengler Chemistry, Incorporation and Conformational Analysis in Peptides, and Activity in Modulators of the Cluster of Differentiation-36 Receptor.
Wei X, Mulumba M, Chemtob S et al.
J Med Chem·2025·Animal·PubMed →
Assessing The Effectiveness of Growth Hormone Releasing Protein-6 in Improving Human Oocyte Maturation and Meiotic Progression in In Vitro Maturation Culture Media.
Ostadian C, Hayati N, Zahiri Sorouri Z et al.
Int J Fertil Steril·2025·Animal·PubMed →
The Ghrelin Analog GHRP-6, Delivered Through Aquafeeds, Modulates the Endocrine and Immune Responses of Sparus aurata Following IFA Treatment.
Rodríguez-Viera L, Caderno A, Martinez R et al.
Biology (Basel)·2025·Animal·PubMed →
A novel butyrylcholinesterase inhibitor induces antidepressant, pro-cognitive, and anti-anhedonic effects in Flinders Sensitive Line rats: The role of the ghrelin-dopamine cascade.
Olivier N, Harvey BH, Gobec S et al.
Biomed Pharmacother·2025·Animal·Neuroprotection, Cognitive Enhancement·PubMed →
Danshen-Chuanxiong-Honghua ameliorates neurological function and inflammation in traumatic brain injury in rats via modulating Ghrelin/GHSR.
Zhang X, Cai Y, Chen M et al.
J Ethnopharmacol·2025·Animal·Neuroprotection·PubMed →
GHSR gene knockout alleviates the liver pathological response in Echinococcus granulosus infection by reducing parasite survival.
Zhu J, Zhou T, Chen G et al.
Vet Res·2025·Animal·Liver Protection·PubMed →
Ghrelin promotes neurologic recovery and neurogenesis in the chronic phase after experimental stroke.
Beuker C, Schreiner U, Strecker JK et al.
Neurol Res Pract·2025·Animal·PubMed →
Subchronic safety assessment of CIGB-500 in beagle dog after repeated daily dose administration over 28 days.
Castro J, Shaikh I, Silo S et al.
Regul Toxicol Pharmacol·2025·Animal·PubMed →
Ghrelin suppresses water intake with a different physiological significance from atrial natriuretic peptide in conscious seawater-acclimated eels.
Kaiya H, Nobata S, Takei Y
J Exp Biol·2025·Animal·PubMed →
Changes in Locomotor Activity Observed During Acute Nicotine Withdrawal Can Be Attenuated by Ghrelin and GHRP-6 in Rats.
Ayman J, Buzás A, Dochnal R et al.
Biomedicines·2025·Animal·PubMed →
Intranasal Delivery of a Ghrelin Mimetic Engages the Brain Ghrelin Signaling System in Mice.
Poelman R, Le May MV, Schéle E et al.
Endocrinology·2025·Animal·Neuroprotection·PubMed →
Novel chimeric peptides based on endomorphins and ghrelin receptor antagonist produced supraspinal antinociceptive effects with reduced acute tolerance in mice.
Wu B, Cheng S, Liu F et al.
Biochimie·2025·Animal·PubMed →
Ghrelin is essential for lowering blood pressure during torpor.
Matsui K, Ida T, Oishi K et al.
Front Endocrinol (Lausanne)·2024·Animal·PubMed →
Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis.
Zhu J, Zhao H, Aierken A et al.
PLoS Negl Trop Dis·2024·Animal·Anti-Inflammatory, Liver Protection·PubMed →
Ghrelin Modulates Voltage-Gated Ca(2+) Channels through Voltage-Dependent and Voltage-Independent Pathways in Rat Gastric Vagal Afferent Neurons.
Goudsward HJ, Ruiz-Velasco V, Stella SL et al.
Mol Pharmacol·2024·Animal·PubMed →
Rikkunshito improves anorexia through ghrelin- and orexin-dependent activation of the brain hypothalamus and mesolimbic dopaminergic pathway in rats.
Yakabi K, Yamaguchi N, Takayama K et al.
Neurogastroenterol Motil·2024·Animal·Neuroprotection·PubMed →
Ghrelin Improves Glucolipotoxicity-Induced Pancreatic β-Cellular Dysfunction and Apoptosis by Inhibiting Endoplasmic Reticulum Stress-Induced IRE1/JNK Pathway.
Li XY, Zhong CR, Wu JC et al.
Discov Med·2024·Animal·PubMed →
Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells.
McKimpson WM, Spiegel S, Mukhanova M et al.
J Cell Biol·2024·Animal·PubMed →
Growth hormone releasing peptide-6 (GHRP-6) prevents doxorubicin-induced myocardial and extra-myocardial damages by activating prosurvival mechanisms.
Berlanga-Acosta J, Cibrian D, Valiente-Mustelier J et al.
Front Pharmacol·2024·Animal·PubMed →
Ghrelin alleviates intestinal ischemia-reperfusion injury by activating the GHSR-1α/Sirt1/FOXO1 pathway.
Liao SS, Zhang LL, Zhang YG et al.
FASEB J·2024·Animal·PubMed →
Combination therapy of Epidermal Growth Factor and Growth Hormone-Releasing Hexapeptide in acute ischemic stroke: a phase I/II non-blinded, randomized clinical trial.
Hernández-Bernal F, Estenoz-García D, Gutiérrez-Ronquillo JH et al.
Front Neurol·2024·Animal·PubMed →
Ghrelin regulates the endoplasmic reticulum stress signalling pathway in gestational diabetes mellitus.
Li X, Ji Q, Zhong C et al.
Biochem Biophys Res Commun·2024 ·Animal·PubMed →
Ghrelin misbalance affects mice embryo implantation and pregnancy success by uterine immune dysregulation and nitrosative stress.
Luque EM, Díaz-Luján CM, Paira DA et al.
Front Endocrinol (Lausanne)·2023·Animal·PubMed →
Differential impact of a ghrelin receptor antagonist or inverse agonist in the electrical kindling model of epilepsy.
Beheshti S, Ershadi S, Zamani F et al.
Epilepsy Res·2023·Animal·PubMed →
Ghrelin Amplifies the Nicotine-Induced Release of Dopamine in the Bed Nucleus of Stria Terminalis (BNST).
Ayman J, Palotai M, Dochnal R et al.
Biomedicines·2023·Animal·PubMed →
In-house standards derived from doping peptides: Enzymatic and serum stability and degradation profile of GHRP and GHRH-related peptides.
González-López NM, Guerra-Acero-Turizo LM, Blanco-Medina I et al.
Biomed Chromatogr·2023·Animal·GH Activity·PubMed →
Desacylghrelin modulates GHS-R1 receptor expression and cell differentiation in placental BeWo cells.
Coria-Caballero V, Jaramillo-Narvaez MD, Leon-Verdin MG et al.
Mol Cell Endocrinol·2023·Animal·PubMed →
Inhibition of ghrelin activity by the receptor antagonist [D-Lys3]-GHRP-6 enhances hepatic fatty acid oxidation and gluconeogenesis in a growing pig model.
Zhang H, Yan X, Lin A et al.
Peptides·2023·Animal·Liver Protection, Weight Loss·PubMed →
The effects and mechanisms of ghrelin upon angiogenesis in human coronary artery endothelial cells under hypoxia.
Wang L, Chen Q, Pang J
Peptides·2023·Animal·PubMed →
Ghrelin Downregulates Lipopolysaccharide/ Leptin-Induced MUC5AC Expression in Human Nasal Epithelial Cells.
Choi YS, Na HG, Bae CH et al.
Clin Exp Otorhinolaryngol·2023·Animal·PubMed →
Meranzin Hydrate Improves Depression-Like Behaviors and Hypomotility via Ghrelin and Neurocircuitry.
Liu YL, Xu JJ, Han LR et al.
Chin J Integr Med·2023·Animal·Anxiety & Mood·PubMed →
Effect of feeding regimen on circadian activity rhythms of food anticipatory by ghrelin hormone in a pig model.
Zhang H, Yan X, Lin A et al.
Nutr Neurosci·2023·Animal·PubMed →
Intracerebroventricular injection of ghrelin receptor antagonist alleviated NAFLD via improving hypothalamic insulin resistance.
Gong Y, Guo Y, Jiang Y et al.
Iran J Basic Med Sci·2022·Animal·PubMed →
Temporal patterns of increased growth hormone secretion in mice after oral administration of L-ornithine: possible involvement of ghrelin receptors.
Taniguchi E, Hattori A, Kurogi K et al.
J Vet Med Sci·2022·Animal·GH Activity·PubMed →
Efficient transdermal delivery of functional protein cargoes by a hydrophobic peptide MTD 1067.
Shin HJ, Bak SU, La HN et al.
Sci Rep·2022·Animal·GH Activity·PubMed →
Antagonization of Ghrelin Suppresses Muscle Protein Deposition by Altering Gut Microbiota and Serum Amino Acid Composition in a Pig Model.
Yan X, Zhang H, Lin A et al.
Biology (Basel)·2022·Animal·PubMed →
The neuropeptide cortistatin attenuates Th17 cell response through inhibition of glycolysis via GHSR1.
Guo Y, Sun D, Zhang Y et al.
Int Immunopharmacol·2022·Animal·PubMed →
Liver-expressed antimicrobial peptide 2 functions independently of growth hormone secretagogue receptor in calorie-restricted mice.
Islam MN, Zhang W, Sakai K et al.
Peptides·2022·Animal·Glycemic Control, Liver Protection·PubMed →
Enteral nutrition alleviated lipopolysaccharides-induced hypercatabolism through ghrelin/GHS-R1α-POMC.
Cao C, Zhang Y, Zuo S et al.
Biochem Biophys Res Commun·2022·Animal·PubMed →
Antagonism of the ghrelin receptor type 1a in the rat brain induces status epilepticus in an electrical kindling model of epilepsy.
Azimzadeh M, Beheshti S
Psychopharmacology (Berl)·2022·Animal·PubMed →
Ghrelin receptor antagonist attenuated sickness behavior and activation of HPA-axis induced by immunological challenge in male rats.
Paula DE Jr, Vilela FC, Giusti-Paiva A
Life Sci·2022·Animal·PubMed →
Role of Dopaminergic and Cannabinoidergic Receptors on Ghrelin-Induced Hypophagia in 5-Day-Old Broiler Chicken.
Farrokhi R, Babapour V, Zendehdel M et al.
Arch Razi Inst·2021·Animal·Neuroprotection·PubMed →
Therapeutic effects of acylated ghrelin-specific receptor GHS-R1a antagonist in islet transplantation.
Chinen K, Sakata N, Yoshimatsu G et al.
Sci Rep·2021·Animal·PubMed →
Ghrelin up-regulates cartilage-specific genes via the ERK/STAT3 pathway in chondrocytes of patients with adolescent idiopathic scoliosis.
Liang ZT, Li J, Rong R et al.
Biochem Biophys Res Commun·2019·Human·PubMed →
Insulinotropic action of bombesin-like peptides mediated by gastrin-releasing peptide receptors in steers.
Zhao HQ, Yao G, Yannaing S et al.
J Anim Sci·2016·Human·Glycemic Control·PubMed →