Research Index
P21 (NSI-189 Peptide Fragment) Research Index
PSI surfaces 20 peer-reviewed studies on P21 (NSI-189 Peptide Fragment), prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
20 studies
The effect of exogenous ciliary neurotrophic factor on cell cycle and neural differentiation markers of in vitro model cells: New insights for future therapeutic approaches.
Ghasemi M, Alizadeh E, Motlagh BF et al.
Cell Biochem Funct·2021·Animal·Neuroprotection·PubMed →
Antitumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma.
Kim JW, Marquez CP, Kostyrko K et al.
Nat Med·2019·Animal·Anti-Inflammatory·PubMed →
Ciliary neurotrophic factor upregulates follistatin and Pak1, causes overexpression of muscle differentiation related genes and downregulation of established atrophy mediators in skeletal muscle.
Tsompanidis A, Vafiadaki E, Blüher S et al.
Metabolism·2016·Animal·Muscle Recovery, Weight Loss·PubMed →
Congenital absence of corticospinal tract does not severely affect plastic changes of the developing postnatal spinal cord.
Huang L, Xian Q, Shen N et al.
Neuroscience·2015·Animal·PubMed →
Different effects of valproic acid on photoreceptor loss in Rd1 and Rd10 retinal degeneration mice.
Mitton KP, Guzman AE, Deshpande M et al.
Mol Vis·2014·Animal·PubMed →
GM-CSF protects rat photoreceptors from death by activating the SRC-dependent signalling and elevating anti-apoptotic factors and neurotrophins.
Schallenberg M, Charalambous P, Thanos S
Graefes Arch Clin Exp Ophthalmol·2012·Animal·PubMed →
Trophic responsiveness of purified postnatal and adult rat retinal ganglion cells.
Ma CH, Taylor JS
Cell Tissue Res·2010·Animal·Longevity·PubMed →
[Exogenous rhCNTF inhibits myoblast differentiation of skeletal muscle of adult human in vitro].
Chen XP, Liu H, Liu SH et al.
Sheng Li Xue Bao·2003·Animal·Muscle Recovery·PubMed →
Inhibition of Ras extracellular-signal-regulated kinase (ERK) mediated signaling promotes ciliary neurotrophic factor (CNTF) expression in Schwann cells.
Abe K, Namikawa K, Honma M et al.
J Neurochem·2001·Animal·PubMed →
Cytokine signal transduction in P19 embryonal carcinoma cells: regulation of Stat3-mediated transactivation occurs independently of p21ras-Erk signaling.
van Puijenbroek AA, van der Saag PT, Coffer PJ
Exp Cell Res·1999·Animal·Anti-Inflammatory, Neuroprotection·PubMed →
Morphological effects of ciliary neurotrophic factor treatment during neuromuscular synapse elimination.
Jordan CL
J Neurobiol·1996·Animal·Muscle Recovery·PubMed →
Constitutive phosphorylation of TrkC receptors in cultured cerebellar granule neurons might be responsible for the inability of NT-3 to increase neuronal survival and to activate p21 Ras.
Zirrgiebel U, Lindholm D
Neurochem Res·1996·Animal·Neuroprotection·PubMed →
A splice variant of the neurotrophin receptor trkB with increased specificity for brain-derived neurotrophic factor.
Strohmaier C, Carter BD, Urfer R et al.
EMBO J·1996·Animal·Neuroprotection·PubMed →
Activation of p44 and p42 MAP kinases is not essential for the survival of rat sympathetic neurons.
Virdee K, Tolkovsky AM
Eur J Neurosci·1995·Animal·PubMed →
Differential regulation of p21ras activation in neurons by nerve growth factor and brain-derived neurotrophic factor.
Carter BD, Zirrgiebel U, Barde YA
J Biol Chem·1995·Animal·Neuroprotection·PubMed →
Transcriptional regulation of the junB promoter: analysis of STAT-mediated signal transduction.
Coffer P, Lutticken C, van Puijenbroek A et al.
Oncogene·1995·Animal·PubMed →
Neutralizing anti-p21ras Fabs suppress rat sympathetic neuron survival induced by NGF, LIF, CNTF and cAMP.
Nobes CD, Tolkovsky AM
Eur J Neurosci·1995·Animal·Anti-Inflammatory, Neuroprotection·PubMed →
Differential requirements for p21ras and protein kinase C in the regulation of neuronal gene expression by nerve growth factor and neurokines.
Johnson JA, Nathanson NM
J Biol Chem·1994·Animal·Neuroprotection·PubMed →
Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons.
Borasio GD, Markus A, Wittinghofer A et al.
J Cell Biol·1993·Animal·PubMed →
Cholinergic neuronal differentiation factors: evidence for the presence of both CNTF-like and non-CNTF-like factors in developing rat footpad.
Rohrer H
Development·1992·Animal·Neuroprotection·PubMed →