Research Index
Orexin-A (Hypocretin-1) Research Index
PSI surfaces 50 peer-reviewed studies on Orexin-A (Hypocretin-1), prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
50 studies
Patient Participation and the Power of Persuasion: A Qualitative Analysis of Patient Testimonies During FDA Drug Advisory Committees.
Eisenkraft Klein D, Mooney H, Bhaskar A et al.
J Health Polit Policy Law·2026·Human·PubMed →
Hierarchical prompting with reasoning large language models for immune checkpoint inhibitor-associated myocarditis evidence extraction pilot study.
Hsu E, Lu SC, Ebrahimi S et al.
Eur Heart J Digit Health·2026·Human·PubMed →
Association between coronary vasomotor dysfunction and autoimmune disease in patients undergoing invasive coronary function testing.
Latif N, Zeng Y, Kostantinis S et al.
Int J Cardiol Heart Vasc·2026·Human·PubMed →
Supporting the Primary Outcomes of the Mirai Trial for the Adjunctive Digital Therapeutic Rejoyn (CT-152) in the Treatment of Major Depressive Disorder: Meaningful Change Analysis in the Montgomery-Åsberg Depression Rating Scale.
Hudgens S, Purnajo I, Floden L et al.
JMIR Form Res·2026·Human·PubMed →
Cost comparison of intravenous immunoglobulin and subcutaneous efgartigimod in patients with chronic inflammatory demyelinating polyneuropathy.
Muley SA, Gucciardi I, Kaisare V et al.
J Med Econ·2026·Human·PubMed →
Predicting unplanned CRRT interruptions in critically Ill burn patients using stacked ensemble machine learning framework.
Li T, Liu H, Chu Z et al.
J Burn Care Res·2026·Human·PubMed →
Defining Clinically Meaningful Within-Patient Changes in Heart Failure: JACC: Heart Failure Position Statement.
Yehya A, Hahn R, Borlaug B et al.
JACC Heart Fail·2026·Human·PubMed →
Effect of a complementary feeding intervention based on iron- and zinc-biofortified pearl millet on the gut microbiota in 12-18-month-old children: a randomized trial.
Huey SL, Cole NL, Pagani I et al.
Nat Commun·2026·Human·PubMed →
Effects of H-coil TMS on suicidality in major depression: A secondary analysis of data from a multisite randomized trial comparing accelerated to once-a-day stimulation.
Roth Y, Tendler A, Brink E et al.
J Affect Disord·2026·Human·PubMed →
Integrated Patient-Derived Xenograft and Patient-Derived Cell Models Reveal Therapeutic Vulnerabilities Beyond Standard-of-Care Therapy in Endometrial Cancer.
Li T, Huang F, Huang X et al.
bioRxiv·2026·Human·PubMed →
Digital clock assessment in South Asian setting: pilot study.
Jagannathan R, Mohan D, Komal R et al.
NPJ Dement·2026·Human·PubMed →
Baroreflex Activation Therapy in Patients with Heart Failure with a Reduced Ejection Fraction.
Ruddy JM, Kroman A, Baicu CF et al.
Card Electrophysiol Clin·2026·Human·PubMed →
Patient-reported outcomes in clinical trials leading to breast cancer drug approvals: are we making them count?
Margolis S, Guirguis AN, Lee C et al.
Breast Cancer Res Treat·2026·Human·PubMed →
Interventional, multicentre investigation of a novel lumbar total joint replacement: propensity matched study design and protocol.
Yarbrough RV, Spece H, Kurtz SM et al.
BMJ Open·2026·Human·PubMed →
Food Effects on the Pharmacokinetics of Single Dose and Steady-State Ralinepag, a Novel Oral Prostacyclin Agonist, in Healthy Volunteers.
Lachant D, Botta CE, Giannakoulas G et al.
Am J Cardiovasc Drugs·2026·Human·PubMed →
A Prospective, Multicenter Randomized Controlled Trial (RCT) of the da Vinci SP(®) Surgical System versus Open Surgery in Nipple-Sparing Mastectomy (NSM) Procedures for Patients with Breast Cancer.
Kopkash K, Piltin M, Jakub J et al.
Ann Surg Oncol·2026·Human·PubMed →
Ironing Out the Details: Advancing Diagnosis and Treatment of Iron Deficiency in Patients with Heart Failure with Preserved Ejection Fraction - A Narrative Review.
Gustafson S, Patel SR, Fudim M et al.
Heart Fail Rev·2026·Human·PubMed →
A Longitudinal Disease Progression Model Characterizing Endoscopic Response and Remission in Crohn's Disease.
Moein A, Langenhorst J, Kassir N
J Pharmacokinet Pharmacodyn·2026·Human·PubMed →
Resmetirom and semaglutide therapy for patients with MAFLD in the MENA region: expert panel recommendations.
Fouad Y, AlNaamani KM, Alawadi F et al.
Expert Rev Endocrinol Metab·2026·Human·Liver Fat (MASLD)·PubMed →
Arimoclomol in infants with Niemann-Pick disease type C: Results from the phase 2/3 open-label pediatric substudy.
Mengel E, Arash-Kaps L, Grunewald S et al.
Mol Genet Metab Rep·2026·Human·PubMed →
Clinico-biological trajectories stratified by combined tau biomarkers in preclinical Alzheimer's disease.
Labrador-Espinosa MA, Franzmeier N, Karagianni S et al.
Alzheimers Res Ther·2026·Human·PubMed →
Pilot randomized trial of intermittent theta-burst stimulation versus H-Coil transcranial magnetic stimulation for treatment-resistant depression.
Desbeaumes Jodoin V, Bousseau E, Trottier-Duclos F et al.
Psychiatry Res·2026·Human·PubMed →
Can We Validate the Musculoskeletal Infection Society Criteria in Patients Suspected of Infection After Transfemoral Osseointegration Surgery?
Bozzay AB, Rivera JA, Rabin SE et al.
Clin Orthop Relat Res·2026·Human·PubMed →
Patient-derived organoids predict personalized drug response and reveal alternative therapeutic options in glioblastoma.
Park J, Qiu M, Cho EJ et al.
Cell Rep Med·2026·Human·PubMed →
Enteral iron dose effect on iron storage, intestinal barrier, and gut microbiome in preterm infants: a randomized clinical trial.
Gibbons JA, Nelson RM, Dabrowski CN et al.
Am J Clin Nutr·2026·Human·PubMed →
Patient Perspectives on Approval Speed vs Evidentiary Certainty in US Cancer Drug Approvals.
Forrest R, Aggarwal A, Tregear M et al.
JAMA Netw Open·2026·Human·PubMed →
Real-world treatment patterns of patients with large B-cell lymphoma over time and into a post-CAR T approval era.
Perales MA, McGuirk JP, Fesen MR et al.
Blood Adv·2026·Human·PubMed →
Use of E-cigarettes With Nicotine Salts and Nicotine Dependence Symptoms in Youth: The National Youth Tobacco Survey, 2024.
Cooper M, Peng MQ, Park-Lee E et al.
J Adolesc Health·2026·Animal·PubMed →
Regenerative Therapies in the Management of Chronic Low Back Pain from Evidence to Practice: An Analytical Summary of the 2025 Comprehensive Evidence-Based Guidelines.
Manchikanti L, Navani A, Jordan S et al.
Pain Physician·2026·Animal·PubMed →
Agent-Specific Clinical Profiles of Antibiotic-Associated Encephalopathy: A Dual-Database Pharmacovigilance Study Using JADER and FAERS.
Itagaki H
Antibiotics (Basel)·2026·Animal·PubMed →
A machine-assisted framework for systematic error analysis in clinical concept extraction.
Fu S, Lu Q, Ahn J et al.
Nat Commun·2026·Animal·PubMed →
Three decades of recombinant human growth hormone research in children born small for gestational age: a bibliometric analysis (1996-2025).
Karacan Küçükali G, Ulukapı HB, Orman B et al.
Front Pediatr·2026·Animal·PubMed →
Technology profiles in FDA-approved new molecular entities, 2013-2024: a latent class analysis.
Jung SK
Daru·2026·Animal·PubMed →
Steady state gait and beyond: Complex mobility tasks in the laboratory reveal gait changes in Parkinson's Disease.
Nagle-Christensen AY, Anderson AJ, Gonzalez MA et al.
Gait Posture·2026·Animal·PubMed →
Clinical associations of pain in an international facioscapulohumeral muscular dystrophy cohort.
Knox RN, Wang LH, Elsheikh B et al.
Neuromuscul Disord·2026·Animal·PubMed →
Respiratory Syncytial Virus Vaccine Effectiveness Among US Older Adults, 2023-2024 Season.
Lu Y, Smith ER, McEvoy R et al.
JAMA Netw Open·2026·Animal·PubMed →
Safety and long-term effectiveness of teduglutide in children with intestinal failure due to short bowel syndrome: a multicenter, post-marketing cohort study.
Jimenez L, Ray A, Mercer D et al.
Pediatr Res·2026·Animal·PubMed →
Clinical Practice Outcomes With Lecanemab for Alzheimer Disease.
Liu AJ, Moghadam AA, Alam MS et al.
Neurol Open Access·2026·Animal·PubMed →
Combination of PARPi and topoisomerase I inhibitors is highly effective in olaparib-resistant ovarian cancer.
Chiappa M, Villa V, Sias F et al.
Exp Hematol Oncol·2026·Animal·PubMed →
Safety profile of entrectinib in NSCLC: Multi-source pharmacovigilance analysis using FAERS and JADER.
Yang J, Liu J, Zhao G et al.
PLoS One·2026·Animal·PubMed →
Deconstructing the Alternative Lengthening of Telomeres: Integromics Prioritizes Five Master Hubs Dictating Clinical Survival and Therapeutic Vulnerabilities.
Armendáriz-Castillo I, Guerrero S, Herrera-Yela A et al.
Biology (Basel)·2026·Animal·PubMed →
The role of plectin as a druggable target in papillary thyroid carcinoma: therapeutic potential of troglitazone.
Lv YC, Zhou JH, Shi TF et al.
Front Immunol·2026·Animal·PubMed →
Transition from drug lag to drug loss in pediatric oncology: a comprehensive evaluation of the Japan-U.S. approval gap.
Yamada K, Sato H, Hirakawa A
Front Pharmacol·2026·Animal·PubMed →
Networked Radiology Imaging and Treatment Planning Systems and FDA Cybersecurity Regulation: A Difference-in-Differences Analysis of 510(k) Clearance Delays.
Lee C
J Imaging Inform Med·2026·Animal·PubMed →
Evaluation of the clinical performance of the JETest Influenza A/B Antigen Rapid Test Kit versus real-time reverse transcription-PCR for influenza detection.
Chen YT, Chen MH, Chin KC et al.
Diagn Microbiol Infect Dis·2026·Animal·PubMed →
[Current Status and Challenges in the Regulation of Weight Management Medical Devices].
Wang Y, Yan J, Jiang X et al.
Zhongguo Yi Liao Qi Xie Za Zhi·2026·Animal·PubMed →
Association Between Proton Pump Inhibitor Use and Malnutrition Risk in the US General Population Using the GLIM Framework (NHANES 1999-2020).
Orsini F, Novella A, Pasina L
Pharmacoepidemiol Drug Saf·2026·Animal·PubMed →
Beyond the Black Box: Is Artificial Intelligence Ready to Reshape Neurosurgical Decision-Making? A Narrative Review.
Singh DB, Dangi Y, Pokharel BP
Health Sci Rep·2026·Animal·PubMed →
Q(AI/ML-SaMD): A Hybrid Health-Technology Quantifiable Quality Metric for Artificial Intelligence/Machine Learning-Based Software as a Medical Device.
Ebad SA
Healthcare (Basel)·2026·Animal·PubMed →
Brivaracetam in Combination with Midazolam and Ketamine Reduces Soman-Induced Seizure and Neurodegeneration in Rats.
Lumley LA, Steier HG, Orta SY et al.
Neurol Int·2026·Animal·PubMed →