Research Index
Noopept (GVS-111) Research Index
PSI surfaces 50 peer-reviewed studies on Noopept (GVS-111), prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
50 studies
The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease.
Radchenko AI, Kuzubova EV, Apostol AA et al.
Acta Naturae·2025·Animal·PubMed →
The Effect of Peptide Semax, an ACTH(4-10) Analogue, on Intracellular Calcium Dynamics in Rat Brain Neurons.
Kolbaev SN, Sharonova IN, Skrebitsky VG
Bull Exp Biol Med·2025·Animal·Neuroprotection·PubMed →
Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice.
Liu R, Chen Y, Huang H et al.
Br J Pharmacol·2025·Animal·Neuroprotection·PubMed →
Genes That Associated with Action of ACTH-like Peptides with Neuroprotective Potential in Rat Brain Regions with Different Degrees of Ischemic Damage.
Filippenkov IB, Shpetko YY, Ales DA et al.
Int J Mol Sci·2025·Animal·Neuroprotection·PubMed →
Semax, a Copper Chelator Peptide, Decreases the Cu(II)-Catalyzed ROS Production and Cytotoxicity of aβ by Metal Ion Stripping and Redox Silencing.
Tomasello MF, Di Rosa MC, Naletova I et al.
Bioinorg Chem Appl·2025·Animal·PubMed →
Robust Multifunctional Films with Excellent EMI Shielding, Anti-Peeling, and Joule Heating Performances Enabled by an Encapsulated Highly Conductive Fabric Strategy.
Chen T, Cheng X, Cai J et al.
Small·2025·Animal·PubMed →
ACTH-like Peptides Compensate Rat Brain Gene Expression Profile Disrupted by Ischemia a Day After Experimental Stroke.
Filippenkov IB, Shpetko YY, Stavchansky VV et al.
Biomedicines·2024·Animal·PubMed →
Antidepressant-like and antistress effects of the ACTH(4-10) synthetic analogs Semax and Melanotan II on male rats in a model of chronic unpredictable stress.
Inozemtseva LS, Yatsenko KA, Glazova NY et al.
Eur J Pharmacol·2024·Animal·Anxiety & Mood·PubMed →
Changes of Transcriptomic Activity in Rat Brain Cells under the Influence of Synthetic Adrenocorticotropic Hormone-Like Peptides.
Filippenkov IB, Glazova NY, Sebentsova EA et al.
Biochemistry (Mosc)·2024·Animal·PubMed →
Effect of ACTH4-10Pro8-Gly9-Pro10 on anti-inflammatory cytokine (IL-4, IL-10, IL-13) expression in acute spinal cord injury models (male Sprague Dawley rats).
Asadullah A, Bajamal AH, Parenrengi MA et al.
F1000Res·2023·Animal·Anti-Inflammatory, Neuroprotection·PubMed →
Synthetic Adrenocorticotropic Peptides Modulate the Expression Pattern of Immune Genes in Rat Brain following the Early Post-Stroke Period.
Filippenkov IB, Remizova JA, Stavchansky VV et al.
Genes (Basel)·2023·Animal·PubMed →
Synthetic corticotropins and the GABA-receptor system: Direct and delayed effects.
Vyunova TV, Andreeva LA, Shevchenko KV et al.
Chem Biol Drug Des·2023·Animal·PubMed →
Insight into Glyproline Peptides' Activity through the Modulation of the Inflammatory and Neurosignaling Genetic Response Following Cerebral Ischemia-Reperfusion.
Stavchansky VV, Filippenkov IB, Remizova JA et al.
Genes (Basel)·2022·Animal·PubMed →
[Results of the application of complex physiotherapeutic neurostimulation in optical neuropathies of various genesis].
Dragon AK, Korchazhkina NB, Sheludchenko VM et al.
Vopr Kurortol Fizioter Lech Fiz Kult·2022·Animal·PubMed →
Diagnostic Value of Different 3-D Shear Wave Elastography Sections in the Diagnosis of Thyroid Nodules.
Hu Z, Lu M, Wang X et al.
Ultrasound Med Biol·2022·Animal·PubMed →
Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models.
Sciacca MFM, Naletova I, Giuffrida ML et al.
ACS Chem Neurosci·2022·Animal·PubMed →
A Mouse Model of Nigrostriatal Dopaminergic Axonal Degeneration As a Tool for Testing Neuroprotectors.
Kolacheva AA, Ugrumov MV
Acta Naturae·2021·Animal·PubMed →
Antistress Action of Melanocortin Derivatives Associated with Correction of Gene Expression Patterns in the Hippocampus of Male Rats Following Acute Stress.
Filippenkov IB, Stavchansky VV, Glazova NY et al.
Int J Mol Sci·2021·Animal·Immune Modulation·PubMed →
Investigation of the effect of a modified fragment of neuropeptide Y on memory phases and extrapolation escape of animals.
Student IOHP, Professor SYSMPD
Ceska Slov Farm·2021·Animal·Cognitive Enhancement·PubMed →
Brain Protein Expression Profile Confirms the Protective Effect of the ACTH((4-7))PGP Peptide (Semax) in a Rat Model of Cerebral Ischemia-Reperfusion.
Sudarkina OY, Filippenkov IB, Stavchansky VV et al.
Int J Mol Sci·2021·Animal·Neuroprotection·PubMed →
[The Peptide Drug ACTH(4-7)PGP (Semax) Suppresses mRNA Transcripts Encoding Proinflammatory Mediators Induced by Reversible Ischemia of the Rat Brain].
Dergunova LV, Dmitrieva VG, Filippenkov IB et al.
Mol Biol (Mosk)·2021·Animal·Neuroprotection·PubMed →
Protective Effects of PGC-1α Activators on Ischemic Stroke in a Rat Model of Photochemically Induced Thrombosis.
Shakova FM, Kirova YI, Silachev DN et al.
Brain Sci·2021·Animal·PubMed →
Morphofunctional State of the Large Intestine in Rats under Conditions of Restraint Stress and Administration of Peptide ACTH((4-7))-PGP (Semax).
Svishcheva MV, Mishina YS, Medvedeva OA et al.
Bull Exp Biol Med·2021·Animal·PubMed →
Semax, synthetic ACTH(4-10) analogue, attenuates behavioural and neurochemical alterations following early-life fluvoxamine exposure in white rats.
Glazova NY, Manchenko DM, Volodina MA et al.
Neuropeptides·2021·Animal·Anxiety & Mood, Neuroprotection·PubMed →
The Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress.
Leonidovna YA, Aleksandrovna SM, Aleksandrovna TA et al.
Curr Rev Clin Exp Pharmacol·2021·Animal·Anti-Inflammatory, Anxiety & Mood·PubMed →
Peptide ACTH(4-7)-PGP: Effects on Various Types of Pain and Pain-Induced Behavior in Rats after Systemic and Central Administration.
Severyanova LA, Kryukov AA, Plotnikov DV et al.
Bull Exp Biol Med·2020·Animal·PubMed →
Composition of Colon Microbiota in Rats Treated with ACTH(4-7)-PGP Peptide (Semax) under Conditions of Restraint Stress.
Svishcheva MV, Mukhina AY, Medvedeva OA et al.
Bull Exp Biol Med·2020·Animal·PubMed →
Novel Insights into the Protective Properties of ACTH((4-7))PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats.
Filippenkov IB, Stavchansky VV, Denisova AE et al.
Genes (Basel)·2020·Animal·PubMed →
Functional Connectomic Approach to Studying Selank and Semax Effects.
Panikratova YR, Lebedeva IS, Sokolov OY et al.
Dokl Biol Sci·2020·Animal·PubMed →
Correction of Lipid Metabolism Disorders in Diabetes Mellitus with Peptide Drugs.
Elagina AA, Lyashev YD, Lyashev AY et al.
Bull Exp Biol Med·2020·Animal·PubMed →
The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations: An incentive for controlling agencies to prepare for future encounters of the kind.
Vanhee C, Francotte A, Janvier S et al.
Drug Test Anal·2020·Animal·PubMed →
The Use of Human Induced Pluripotent Stem Cells for Testing Neuroprotective Activity of Pharmacological Compounds.
Novosadova EV, Arsenyeva EL, Antonov SA et al.
Biochemistry (Mosc)·2019·Animal·Neuroprotection·PubMed →
An integrated approach to study the molecular aspects of regulatory peptides biological mechanism.
Vyunova TV, Andreeva LA, Shevchenko KV et al.
J Labelled Comp Radiopharm·2019·Animal·Cognitive Enhancement, Anxiety & Mood·PubMed →
Experimental Substantiation of Application of Semax as a Modulator of Immune Reaction on the Model of "Social" Stress.
Samotrueva MA, Yasenyavskaya AL, Murtalieva VK et al.
Bull Exp Biol Med·2019·Animal·Immune Modulation, Neuroprotection, Anxiety & Mood·PubMed →
[The efficacy of semax in the tretament of patients at different stages of ischemic stroke].
Gusev EI, Martynov MY, Kostenko EV et al.
Zh Nevrol Psikhiatr Im S S Korsakova·2018·Human·PubMed →
Effects of Semax on the Default Mode Network of the Brain.
Lebedeva IS, Panikratova YR, Sokolov OY et al.
Bull Exp Biol Med·2018·Animal·PubMed →
Modulation of GABA- and Glycine-Activated Ionic Currents with Semax in Isolated Cerebral Neurons.
Sharonova IN, Bukanova YV, Myasoedov NF et al.
Bull Exp Biol Med·2018·Animal·Neuroprotection·PubMed →
Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology.
Galati C, Spinella N, Renna L et al.
Beilstein J Nanotechnol·2017·Animal·PubMed →
Studying the Toxic Effects of Some Biologically Active Peptides on the Model of Mouse Embryonic Stem Cells.
Kobylyanskii AG, Zolotarev YA, Andreeva LA et al.
Bull Exp Biol Med·2017·Animal·Neuroprotection·PubMed →
Rhythmoinotropic Response of Papillary Muscles in Rats with Different Severity of Postinfarction Cardiosclerosis.
Kondratieva DS, Afanasiev SA, Usov VY et al.
Bull Exp Biol Med·2017·Animal·Neuroprotection·PubMed →
Changes in Sympathetic Innervation of the Heart in Rats with Experimental Myocardial Infarction. Effect of Semax.
Gavrilova SA, Markov MA, Berdalin AB et al.
Bull Exp Biol Med·2017·Animal·PubMed →
Peptides semax and selank affect the behavior of rats with 6-OHDA induced PD-like parkinsonism.
Slominsky PA, Shadrina MI, Kolomin TA et al.
Dokl Biol Sci·2017·Animal·Anxiety & Mood·PubMed →
Influence of ACTG(4-7)-PGP (Semax) on Morphofunctional State of Hepatocytes in Chronic Emotional and Painful Stress.
Ivanov AV, Bobyntsev II, Shepeleva OM et al.
Bull Exp Biol Med·2017·Animal·Liver Protection·PubMed →
[POSSIBLE DRUG CORRECTION OF LIPID METABOLISM DISTURBANCES ASSOCIATED WITH METABOLIC SYNDROME IN PATIENTS WITH PSORIASIS].
Dontsova EV
Eksp Klin Farmakol·2015·Human·Metabolic Syndrome, Neuroprotection·PubMed →
[The results of the application of the pre-formed physical factors and neuroprotective therapy for the rehabilitative treatment of the patients with diabetic retinopathy].
Nazarova GA, Konchugova TV, Iurova OV et al.
Vopr Kurortol Fizioter Lech Fiz Kult·2013·Human·Neuroprotection·PubMed →
The effect of Semax and its C-end peptide PGP on the morphology and proliferative activity of rat brain cells during experimental ischemia: a pilot study.
Stavchansky VV, Yuzhakov VV, Botsina AY et al.
J Mol Neurosci·2011·Human·Neuroprotection·PubMed →
[The study of chronic partial denervation and quality of life in patients with motor neuron disease treated with semax].
Serdiuk AV, Levitskiĭ GN, Miasoedov NF et al.
Zh Nevrol Psikhiatr Im S S Korsakova·2007·Human·Muscle Recovery, Neuroprotection·PubMed →
[Semax in prevention of disease progress and development of exacerbations in patients with cerebrovascular insufficiency].
Gusev EI, Skvortsova VI, Chukanova EI
Zh Nevrol Psikhiatr Im S S Korsakova·2005·Human·PubMed →
[Semax in the treatment of glaucomatous optic neuropathy in patients with normalized ophthalmic tone].
Kurysheva NI, Shpak AA, Ioĭleva EE et al.
Vestn Oftalmol·2001·Human·Neuroprotection·PubMed →
[Evaluation of therapeutic effect of new Russian drug semax in optic nerve disease].
Polunin GS, Nurieva SM, Baiandin DL et al.
Vestn Oftalmol·2000·Human·Neuroprotection·PubMed →