MOTS-c — Indexed Studies

Repeated Heat Stress Modulates the Levels of the Mitokines MOTS-C and FGF21 in Active Men during Calf Muscle Immobilization.

Elhusseiny R, Ihsan M, Labidi M et al.

Reduced serum levels of mitochondria-derived peptide MOTS-c in patients with obstructive sleep apnea.

Luo Z, Ji R, Ye R et al.

Circulating PGC-1α and MOTS-c Peptide as Potential Mitochondrial Biomarkers in Patients Undergoing Aortic Valve Replacement.

Sánchez-Quintero MJ, Iboleón A, Martín Chaves L et al.

Effects of Glucagon-Like Peptide-1 Receptor Agonists, Sodium-Glucose Cotransporter-2 Inhibitors, and Their Combination on Neurohumoral and Mitochondrial Activation in Patients With Diabetes.

Ikonomidis I, Pavlidis G, Pliouta L et al.

MOTS-c Levels and Sarcopenia Risk in Chronic Peritoneal Dialysis Patients: A Pilot Study.

Zicarelli M, Greco M, Roumeliotis S et al.

Exploring the therapeutic potential of MOTS-c in age-related macular degeneration: from cellular responses to patient-derived cybrids.

Mohtashami Z, Schneider K, Azimi R et al.

Effects of empagliflozin and dapagliflozin on serum humanin, MOTS-c levels, nitrosative stress, and ferroptosis parameters in diabetic patients with heart failure.

Asil H, Demiryürek AT, Düzen IV et al.

The Mitochondrial-Derived Peptide MOTS-c May Refine Mortality and Cardiovascular Risk Prediction in Chronic Hemodialysis Patients: A Multicenter Cohort Study.

Bolignano D, Greco M, Presta P et al.

Impact of Radiation Therapy on Serum Humanin and MOTS-c Levels in Patients with Lung or Breast Cancer.

Kavak AG, Karslioglu I, Saracaloglu A et al.

The relationship of circulating MOTS-c level with liver fibrosis and metabolic components in patients with metabolic dysfunction-associated fatty liver disease.

Kirik A, Dogru T, Yanik B et al.

Evaluation of Serum Humanin and MOTS-c Peptide Levels in Patients with COVID-19 and Healthy Subjects.

Saracaloglu A, Mete AÖ, Ucar DF et al.

Serum MOTS-c levels remain unchanged in patients with preeclampsia.

Tok A, Serdar O, Kandilcik OF et al.

Circulating levels of MOTS-c in patients with breast cancer treated with metformin.

Cuyàs E, Verdura S, Martin-Castillo B et al.

MOTS-c as a predictor of coronary lesions and complexity in patients with stable coronary artery disease.

Yaşar E, Çakmak T, Bayramoğlu A et al.

Effect of aerobic and resistance exercise on the mitochondrial peptide MOTS-c in Hispanic and Non-Hispanic White breast cancer survivors.

Dieli-Conwright CM, Sami N, Norris MK et al.

Acute endurance exercise stimulates circulating levels of mitochondrial-derived peptides in humans.

von Walden F, Fernandez-Gonzalo R, Norrbom J et al.

β-Amyloid and mitochondrial-derived peptide-c are additive predictors of adverse outcome to high-on-treatment platelet reactivity in type 2 diabetics with revascularized coronary artery disease.

Ikonomidis I, Katogiannis K, Kyriakou E et al.

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome.

Raijmakers RPH, Jansen AFM, Keijmel SP et al.

Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction.

Qin Q, Delrio S, Wan J et al.

aMitochondrial-Derived Peptide MOTS-c Targets SLC7A11 to Preserve Spermatogenesis by Suppressing Ferroptosis.

Liu S, Ru K, Shen YJ et al.

Mitochondrial open reading frame of the 12S rRNA type-c (MOTS-c) primes adrenal cortex metabolism without directly driving steroidogenesis.

Blatkiewicz M, Kaminski K, Sobalska-Kwapis M et al.

Effects of graviola oil extract on fattening performance and circadian rhythms of adipokine, cardiac and mitochondrial function markers in lambs.

Kotan GC, Bayraktar B

Mitochondria-derived peptide MOTS-c alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice by activating Nrf2 pathway.

Chen D, Zhou MH, Zhu WY et al.

MOTS-c Protects Against Acetaminophen-induced Liver Injury through the MAPK Signaling Pathway.

Li N, Xu Y, Chen Q et al.

Mitochondrial-derived peptides MOTS-c and humanin attenuate dexamethasone-induced atrophy in human skeletal muscle cells.

Elhusseiny R, Ihsan M, Bellefroid T et al.

Aerobic exercise and MOTS-c attenuate diabetic myocardial fibrosis via inhibition of the THBS1/TGF-β signaling pathway.

Li Z, Wang T, Fu Y et al.

Therapeutic Effects of MOTS-c in the Valproic Acid-Induced Autism Model in Rats: Role of Tetrahydrobiopterin and Brain-Derived Neurotrophic Factor.

Güvenir Seven S, Sahin H, Erkanlı Şentürk G et al.

Reduced serum and skeletal muscle MOTS c levels in women with polycystic ovary syndrome are associated with mitochondrial dysfunction.

Kutuk IS, Akin S, Demirel H et al.

MOTS-c attenuates cardiac dysfunction following high altitude exposure by promoting mitophagy.

Feng Z, Xing Y, Lou J et al.

Exogenous MOTS-c mitigates myocardial ischemia-reperfusion injury: experimental and in silico evidence from rat heart models.

Santhanam SS, Jayaraman S, Kurian GA

Systemic MOTS-c levels are increased in adults with obesity in association with metabolic dysregulation and remain unchanged after weight loss.

Yoon SH, Yuan F, Zhu X et al.

MOTS-c improves intrinsic muscle mitochondrial bioenergetic health and efficiency in a PGC-1α/AMPK-dependent manner.

Gudiksen A, Hansen CC, van der Stede T et al.

Serum Mitochondrial Open Reading Frame of the 12S rRNA-c (MOTS-c) Dynamics as a Complementary Marker of Treatment Response in Newly Diagnosed Multiple Myeloma: A Prospective Analysis.

Erol V, Avci E, Kabukcu Hacioglu S et al.

Muscle-Targeted Nanocomposite Therapy Alleviates Age-Related Sarcopenia via Antioxidant and Metabolic Reprogramming.

Liu Z, Shen Z, Lu H et al.

Insights into the Biomarker Potential of Humanin and Mots-c Expression and Telomere Length in Alzheimer's Disease.

Rodríguez-Esparragón F, Cazorla-Rivero SE, Torrealba E et al.

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice.

Chen D, Zhao HM, Sun XL et al.

MOTS-c attenuates mitochondrial dysfunction induces pyroptosis and cartilage degradation in osteoarthritis via an Nrf2-Dependent Mechanism.

Li K, Yang T, Chen F et al.

MOTS-C levels ın ındividuals with and without obesity and ıts association with ınflammation, insulin resistance and endothelial dysfunction.

Ozkaya DY, Haymana C, Demirci I et al.

Mitochondrial-encoded peptide MOTS-c prevents pancreatic islet cell senescence to delay diabetes.

Kong BS, Lee H, L'Yi S et al.

Characterization of the Avian Mitochondrial-Derived Peptide MOTS-c and Its Potential Role as a Metabolic Regulator.

Shu X, Liu J, Xu B et al.

Diagnostic relevance of Humanin, GAS5 and miR-21/miR-103 in prostate disease risk stratification.

Coradduzza D, Cruciani S, Sibono L et al.

A mitochondrial-derived peptide MOTS-c contributes to the protective effect against brain injury associated with LPS-induced sepsis by strengthening the blood-brain barrier's ultrastructure.

Bai Y, Wu H, Wang X et al.

Mitochondria-derived peptide MOTS-c restores mitochondrial respiration in type 2 diabetic heart.

Pham T, Taberner A, Hickey A et al.

The impact of mitokine MOTS-c administration on the soleus muscle of rats subjected to a 7-day hindlimb suspension.

Sidorenko DA, Lvova ID, Tyganov SA et al.

Mitochondria-derived peptide MOTS-c and its role in OSA pathogenesis: a potential therapeutic target?

Edwards BA, Joosten SA, Landry SA

MOTS-c-modified functional self-assembly peptide hydrogels enhance the activity of nucleus pulposus-derived mesenchymal stem cells of intervertebral disc degeneration.

Lin Y, Yang RY, Li J et al.

MOTS-c mimics exercise to combat diabetic liver fibrosis by targeting Keap1-Nrf2-Smad2/3.

Chen F, Li Z, Wang T et al.

MOTS-c attenuates lung ischemia-reperfusion injury via MYH9-Dependent nuclear translocation and transcriptional activation of antioxidant genes.

Li X, Zhan F, Qiu G et al.

MOTS-c as a Potential Diagnostic-prognostic Biomarker for Myocardial Infarction.

Cakmak A, Yazgan B

MOTS-c Promotes Glycolysis via AMPK-HIF-1α-PFKFB3 Pathway to Ameliorate Cardiopulmonary Bypass-induced Lung Injury.

Shen Z, Lu P, Jin W et al.