Research Index
LL-37 Research Index
PSI surfaces 50 peer-reviewed studies on LL-37, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
50 studies
[Evaluation of Serum LL-37 Levels in Patients with Brucellosis and Their Relationship with Clinical Course].
Gögebakan K, Özkurt Z, Öztürk N
Mikrobiyol Bul·2026·Human·PubMed →
LL-37 Inhibits EV71 Infection by Upregulating STAC via the EGFR-ERK Signaling Pathway.
Zhang J, Zhang H, Chen Y et al.
Viruses·2026·Animal·PubMed →
Antimicrobial Peptides and Systemic Inflammation: A Network Analysis.
Pinheiro da Silva F, Soriano FG, Hajjar LA
Immun Inflamm Dis·2026·Animal·Antimicrobial, Anti-Inflammatory, Immune Modulation·PubMed →
Targeting Drug-Resistant Tuberculosis with Antimicrobial Peptides: Opportunities and Challenges.
Ahmad A, Wasim R, Islam A et al.
Curr Protein Pept Sci·2026·Animal·PubMed →
LL-37-ApoB-100 Complex Serves as a Biomarker of Coronary Artery Disease.
Fang Y, Zhang Z, Cao Q et al.
Arterioscler Thromb Vasc Biol·2026·Animal·PubMed →
Using biomarkers to detect intramammary infections in dairy cows at dry-off.
Viora L, Pepler PT, O'Reilly EL et al.
Res Vet Sci·2026·Animal·PubMed →
Design and Screening of the Peptide SAMP-12aa Derived from LL-37, Which Exhibits Anti-H. Pylori Activity and Immunomodulatory Effects.
Lu J, Wang Q, Qin M et al.
Molecules·2026·Animal·PubMed →
Novel Hybrid Peptide ML-2 with Antibacterial and Antibiofilm Activity Against Pseudomonas aeruginosa.
Wu S, Shi Y, He Y et al.
Curr Microbiol·2026·Animal·Antimicrobial·PubMed →
LL-37 selectively targets Plasmodium-infected erythrocytes and exhibits antimalarial activity.
He X, Zhang Y, Lou J et al.
PLoS Pathog·2026·Animal·PubMed →
Amoebicidal effect of Antimicrobial Peptides against Acanthamoeba castellanii: A study of cell death using Fluorescence imaging systems.
Sifaoui I, Rodríguez-Expósito RL, Reyes-Batlle M et al.
Acta Trop·2026·Animal·PubMed →
A hedgehog cathelicidin-derived peptide exhibits antiviral activity against herpes simplex virus type 1 infection.
Deng E, Pei Y, Yuan K et al.
Front Microbiol·2026·Animal·PubMed →
Influence of N- and O-glycosylation on structural properties and biological activity of a C-terminal LL-37 fragment.
Grzywacz D, Nuti F, Żamojć K et al.
Carbohydr Res·2026·Animal·Antimicrobial·PubMed →
Endogenous cathelicidin protects against Toxoplasma gondii-associated liver damage.
Tan YL, Cavalcante P, Cirone KM et al.
Infect Immun·2026·Animal·PubMed →
Immunomodulatory Effects of the Antimicrobial Peptide KR-20: Implications for Trichomoniasis.
Ramírez-Ledesma MG, Ávila EE, Alva-Murillo N
Molecules·2026·Animal·Antimicrobial, Immune Modulation·PubMed →
Structural determinants of glycosaminoglycan oligosaccharides as LL-37 inhibitors in breast cancer.
Le Fournis C, Maszota-Zieleniak M, Kulesza A et al.
Glycobiology·2026·Animal·PubMed →
Low-Power Short-Pulse-Width Fractional Microneedle Radiofrequency Relieves LL37-Induced Rosacea-Like Skin Inflammation.
Xu Z, Shen S, Zhao J et al.
J Cosmet Dermatol·2026·Animal·Wound Healing, Anti-Inflammatory·PubMed →
Identification and characterization of novel antimicrobial peptides from Camelus dromedarius: a combined bioinformatics and experimental study.
Al-Mamari W, Elhag Y, Al Bulushi S et al.
Front Immunol·2026·Animal·Antimicrobial·PubMed →
CRISPR/Cas9-engineered Salmonella phage displaying antimicrobial peptide LL37 for enhanced antibacterial activity.
Jo SJ, Park SC, Kim SG
Int J Antimicrob Agents·2026·Animal·Antimicrobial·PubMed →
Injectable self-healing hydrogel loaded with a self-assembling LL-37 derivative for treating infected skin wounds.
Ba Q, Yao J, Tian H et al.
Int J Pharm·2026·Animal·Wound Healing, Antimicrobial·PubMed →
Development of nanobody-conjugated LL37 for synergistic therapy against MDR Acinetobacter baumannii.
Thaiprayoon A, Oonanant W, Boonsilp S et al.
mSphere·2026·Animal·Antimicrobial·PubMed →
Regulation of virulence factors of Pseudomonas aeruginosa by Scutellaria baicalensis, Prunella vulgaris and antimicrobial peptide LL-37.
Xiao Q, Du K, Luo L et al.
J Med Microbiol·2026·Animal·Antimicrobial·PubMed →
Discovery and classification of new reptile cathelicidins by genome mining: study of their structure and genomic organization in Testudines and Squamata.
Otazo-Pérez A, López MR, González-Acosta S et al.
Dev Comp Immunol·2026·Animal·PubMed →
The Ly6g(high) Neutrophil Subset Dictates Breast Cancer Lung Metastasis via CD8(+) T Cell Death.
Wang R, Liu X, Hou Y et al.
Cancer Commun (Lond)·2026·Animal·PubMed →
Cathelicidin CATH-2 suppresses the NF-κB/ROS/NLRP3 signaling pathway via regulating mTOR-dependent autophagy during Streptococcus suis infection.
Xu L, Lu Y, Xu S et al.
Vet Res·2026·Animal·PubMed →
Cathelicidin-Ka, the first frog-derived TLR2 and TLR4 agonist, induces macrophage activation and promotes inflammation.
Chai J, Wu J, Zhang S et al.
Cell Mol Life Sci·2026·Animal·Anti-Inflammatory·PubMed →
Single Amino Acid Modulates Antimicrobial Peptide Cooperativity between LL-37 and HNP1.
Schwitter AM, Yasuda T, Li X et al.
Langmuir·2026·Animal·PubMed →
Immunomodulatory activities of bovine host defense peptides (HDPs): context-dependent roles in inflammation and immune priming.
Saubi C, Meade KG, Travé-Asensio S et al.
BMC Vet Res·2026·Animal·Anti-Inflammatory, Antimicrobial·PubMed →
Stripping cell-free DNA from its immune complex is essential for inflammation control using DNase I.
Chen S, Du Y, Zhu C et al.
Biomaterials·2026·Animal·Anti-Inflammatory·PubMed →
Identification and characterization of broad-spectrum cathelicidin family antimicrobial peptides from the pygmy sperm whale Kogia breviceps.
Zhang P, Ye Z, Dou H et al.
Biochem Pharmacol·2026·Animal·Antimicrobial·PubMed →
LL-37-derived peptide shows promising antimicrobial potential against multidrug-resistance pathogens.
Asmamaw D, Cai H, Prateeksha P et al.
Eur J Med Chem·2026·Animal·Antimicrobial·PubMed →
Functional characterization of Cr-CATHs: Novel antimicrobial peptides from the coastal bird Chroicocephalus ridibundus.
Dou H, Li S, Zhang P et al.
Biochimie·2026·Animal·Antimicrobial·PubMed →
LL37-induced mitochondrial stress activates the mtDNA/cGAS/STING pathway to promote mast cell-mediated rosacea inflammation.
Sun R, Fan H, Ma Q et al.
Free Radic Biol Med·2026·Animal·Anti-Inflammatory·PubMed →
Pneumococcal S protein coordinates cell wall modification and repair to resist host antimicrobials.
Burnier J, Gallay C, Bruce KE et al.
Nat Microbiol·2026·Animal·Antimicrobial·PubMed →
Skin-Homing Potential of Peripheral Immune Cells From Psoriasis Patients and the Effects of LL-37 on Their Secretion of Chemokines During Psoriasis-Mimicking Stimulation.
Sigurgrímsdóttir H, Eysteinsdóttir JH, Kristjánsson ÁK et al.
Scand J Immunol·2025·Human·Wound Healing·PubMed →
No difference in inflammatory mediator expression between mast cell-rich and mast cell-poor rosacea lesions in Korean patients: a comparative study.
Lee JJ, Kwon BR, Lee MY et al.
Ewha Med J·2025·Human·PubMed →
Assessment of serum cathelicidin in chronic spontaneous urticaria patients.
El Mahdi AR, Melek N, AbdAllah AM et al.
Egypt J Immunol·2025·Human·PubMed →
Distinct anti-microbial peptides expression patterns and microbiome profiles in skin of Tunisian endemic Pemphigus foliaceus patients.
Abida O, Ramiro R, Bahloul E et al.
Arch Dermatol Res·2025·Human·Wound Healing·PubMed →
The Immunomodulatory Activity of High Doses of Vitamin D in Critical Care Patients with Severe SARS-CoV-2 Pneumonia-A Randomized Controlled Trial.
Gonçalves AM, Velho S, Rodrigues B et al.
Nutrients·2025·Human·PubMed →
Study of cathelicidin (LL-37) immunoexpression in the skin of vitiligo patients.
Elgarhy LH, Ramadan BRR, Sallam FAA et al.
Arch Dermatol Res·2025·Human·Wound Healing·PubMed →
Increased cathelicidin LL-37 colonic expression is associated with tumor progression in colorectal cancer.
Wlodarczyk J, Dziki L, Fichna J
J Physiol Pharmacol·2025·Animal·PubMed →
Epithelial Heparan Sulfate Promotes Staphylococcus aureus Corneal Infection by Inhibiting Cathelicidins.
Hayashida K, Esko JD, Gallo RD et al.
Proteoglycan Res·2025·Animal·PubMed →
Synthetic antimicrobial peptide LD4-PP protects the host against E. coli-induced cell death.
Mohanty S, White JK, Yin Y et al.
Front Immunol·2025·Animal·Antimicrobial·PubMed →
Immunomodulatory effects of QsCATH on macrophages: transcriptomic insights and molecular docking analysis.
Qiao F, Qian XY, Wu JL et al.
Sci Rep·2025·Animal·Anti-Inflammatory, Antimicrobial·PubMed →
Novel integrated approach modeling proanthocyanidins and bacteriophages to combat multidrug Salmonella Typhimurium in challenged broilers.
Al-Khalaifah HS, Ibrahim D, Abdelfattah-Hassan A et al.
Front Vet Sci·2025·Animal·PubMed →
LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.
Fan H, Sun R, Ma Q et al.
Front Immunol·2025·Animal·Anti-Inflammatory·PubMed →
Cathelicidin LL37-loaded extracellular vesicles from Edwardsiella piscicida promote antibacterial and wound-healing activity.
Dias MKHM, Jayathilaka EHTT, De Zoysa M
Sci Rep·2025·Animal·Antimicrobial, Wound Healing·PubMed →
Molecular response to the non-lytic peptide bac7 (1-35) triggers disruption of Klebsiella pneumoniae biofilm.
Beckman I V RL, Martinez B, Santiago FZ et al.
PLoS Pathog·2025·Animal·Antimicrobial·PubMed →
Potential Vaccine or Antimicrobial Reagents: Simple Systems for Producing Lambda Display Particles (LDP) and Sheathed Lambda DNA Vaccine Particles (LDNAP).
Hayes S
Viruses·2025·Animal·PubMed →
Enhancing Transdermal Delivery: The Role of Gecko-Derived Cathelicidin Peptide G3CY-10 in UV-Induced Skin Photoaging.
Wang Y, Ma Z, Li F et al.
Biomolecules·2025·Animal·Skin & Cosmetic, Wound Healing·PubMed →
Therapeutic effect of an MRGPRX2/MRGPRB2 antagonist on LL-37-induced rosacea-like inflammation in mice.
Chow BKC, Choi YG, Wong TK et al.
Inflamm Res·2025·Animal·Wound Healing, Anti-Inflammatory·PubMed →