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INDEXED STUDIES

Kisspeptin — Indexed Studies

50 most recent studies indexed by PSI from PubMed and clinical databases

Showing 50 of 50 studies

First clinical use of the kisspeptin analog TAK-683 in the treatment of a follicular cyst in a goat: case report.

Uyanık G, Yüksel M, Kara F et al.

Vet Res Commun(2026)
Human
PubMed

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review.

Menekse B, Ucgul E, Bakir A et al.

Exp Ther Med(2026)
Human
PubMed

Comparative Analysis of Kisspeptin Levels and KISS1 Gene Polymorphism in Patients with Polycystic Ovary Syndrome (PCOS): Correlation with the Luteinizing Hormone-Follicle-Stimulating Hormone Ratio and PCOS-Associated Variables.

Talukdar C, Choudhary SS, Talukdar PM et al.

Cureus(2025)
Human
PubMed

Effect of post-mating TAK-683 (Kisspeptin analog) treatment on luteal morphology and function in suckling goats with lactational anestrus.

Uyanık G, Yüksel M, Abay M et al.

Anim Reprod Sci(2026)
Human
PubMed

Intravenous kisspeptin 112-121 bolus does not acutely impact circulating vasopressin in humans.

Galbiati F, Plessow F, Plummer L et al.

J Neuroendocrinol(2026)
Human
PubMed

Serum Kisspeptin levels in patients undergoing maintenance hemodialysis: a case-control study protocol.

Yang B, Zheng N, Shao Q et al.

BMC Nephrol(2025)
Human
PubMed

Concentration-QTc Modeling to Support Clinical Development of Fezolinetant.

Nielsen JC, Saito M, Wang X et al.

Clin Pharmacol Drug Dev(2026)
Human
PubMed

Effect of kisspeptin with or without cabergoline on the estrus cycle and reproductive hormones in female dogs.

Bozkurt G, Agaoglu AR, Aslan S et al.

Theriogenology(2026)
Human
PubMed

Evaluation and Treatment of Patients With Hypothalamic Hypogonadism.

Himel R, Keefe D

Obstet Gynecol Surv(2025)
Human
PubMed

Evaluation of Betatrophin, Chemerin, and Kisspeptin Levels in Acromegaly Patients.

Cayan DA, Topsakal S, Avci E

Endocr Metab Immune Disord Drug Targets(2025)
Human
PubMed

Intranasal kisspeptin administration rapidly stimulates gonadotropin release in humans.

Mills EG, Silva MSB, Delli V et al.

EBioMedicine(2025)
Human
PubMed

Corrigendum to "Kisspeptin-54 attenuates oxidative stress and neuronal apoptosis in early brain injury after subarachnoid hemorrhage in rats via GPR54/ARRB2/AKT/GSK3β signaling pathway" [Free Radic Biol Med.171 (2021) 99-111].

Huang Y, Guo Y, Huang L et al.

Free Radic Biol Med(2026)
Animal
PubMed

GABA receptor modulation of arcuate kisspeptin neuron bursting and synchronization activity in female mice.

Eddleston T, Morris PG, Herbison AE

J Neuroendocrinol(2026)
Animal
Neuroprotection
PubMed

Molecular and functional characterization of the kisspeptin receptor Kissr3 in the large yellow croaker (Larimichthys crocea).

Yuan H, Huang B, Zhang R et al.

Comp Biochem Physiol B Biochem Mol Biol(2026)
Animal
PubMed

Robust serotonin activation of the kisspeptin GnRH pulse generator in male and female mice.

Morris PG, Liu X, Birt E et al.

Endocrinology(2026)
Animal
PubMed

The Expression of Kisspeptin Receptor, Catsper 3 and Acrosome Integrity in Oligozoospermic and Normozoospermic Individuals.

Ünlükal N, Aniç S, Dursunoğlu D et al.

Genes (Basel)(2026)
Animal
PubMed

Cadmium-Induced Neuroendocrine Alterations: Gene Expression of the Kisspeptin-GnRH Axis and Delayed Puberty in Male Rats.

Arteaga-Silva M, Cornejo de la Concha EM, Landero-Huerta DA et al.

Toxics(2026)
Animal
PubMed

Kobayashi Award 2024: Cyclic regulation of the reproductive neuroendocrine system in fish: Using migratory fish as a model.

Ando H

Gen Comp Endocrinol(2026)
Animal
PubMed

Effects of Microplastics on the Central Reproductive Neuroendocrine System in a Sheep Model.

Młotkowska P, Osuch B, Marciniak E et al.

Int J Mol Sci(2026)
Animal
PubMed

Microglia Rank signaling regulates GnRH neuronal function and the hypothalamic-pituitary-gonadal axis.

Collado-Sole A, Borjini N, Zhai J et al.

Science(2026)
Animal
PubMed

Neuroendocrine effects of exogenous adropin administration on the hypothalamic pituitary testicular axis in male rats.

Eraslan E, Tanyeli A, Güler MC et al.

Turk J Med Sci(2026)
Animal
PubMed

Novel KISS1 Gene Mutation Leading to Male Hypogonadotropic Hypogonadism.

Wittner L, Mahindrakar S, Yasin A et al.

Exp Clin Endocrinol Diabetes(2026)
Animal
PubMed

Progestogen priming is not essential to trigger ovulation in seasonal anoestrus ewes injected twice with a synthetic kisspeptin analogue.

Lomet D, Robert V, Decourt C et al.

Animal(2026)
Animal
PubMed

Kisspeptin Restores Placental mTOR Signaling and Improves Glucose Homeostasis Mediators Disrupted by Maternal Hypothyroidism in Rats.

Santos BR, Dos Anjos Cordeiro JM, Santos LC et al.

Acta Physiol (Oxf)(2026)
Animal
PubMed

Investigation of Radiolabeled KISS1R Ligands as Promising Tools for Diagnosis and Treatment of Triple-Negative Breast Cancer.

Taş H, Schäfer M, Shuja-Uddin A et al.

Mol Pharm(2026)
Animal
PubMed

GPR54 regulates non-small cell lung cancer development via dopa decarboxylase.

Hwang HH, Lee SY, Lee C et al.

Signal Transduct Target Ther(2026)
Animal
PubMed

Targeting the NR5A1-KISS1R-EMT axis with a small-molecule inhibitor suppresses lung adenocarcinoma progression and metastasis.

Wang D, Hui K, Yuan C et al.

Cell Signal(2026)
Animal
PubMed

Sodium benzoate induces reproductive toxicity via hormonal disruption, ovarian damage and altering kisspeptin/RFRP-3 expression.

Khan S, Attaullah M, Zubair M et al.

Regul Toxicol Pharmacol(2026)
Animal
PubMed

In vitro differentiation of the hypothalamic KNDy neuron, a master regulator for reproduction, from mouse embryonic stem cells.

Miyake N, Suga H, Osuka S et al.

Reprod Biol Endocrinol(2026)
Animal
Neuroprotection
PubMed

Direct adverse effects of fipronil sulfone, diisopentyl phthalate and disperse red 60 on zebrafish hepatocytes.

Leite BA, de Oliveira DP, Unniappan S

Toxicol Rep(2026)
Animal
PubMed

Functional interactions between anteroventral periventricular kisspeptin neurons and gonadotropin-releasing hormone neurons in female mice.

Starrett JR, Krasner D, Phillips CD et al.

bioRxiv(2026)
Animal
PubMed

Evolution of neurohormone function revealed by actions of kisspeptin-type peptides in an echinoderm.

Islam T, Yañez-Guerra LA, Semmens DC et al.

BMC Biol(2026)
Animal
PubMed

Preoptic kisspeptin-nNOS-GnRH (KiNG) neuronal network regulates LH rhythmicity through activation-inhibition in mice.

Delli V, Moulinier M, Lazaridou AM et al.

Nat Commun(2026)
Animal
Neuroprotection
PubMed

Kisspeptin improves local ovarian insulin resistance in PCOS by modulating the PI3K/AKT/GLUT4 signaling pathway.

Sun N, Sun P, Sun L et al.

PLoS One(2026)
Animal
Glycemic Control
PubMed

High-Fat Diet Induces Epigenetic and Metabolic Changes in Kisspeptin Neurons in Association with Obesity and Male Secondary Hypogonadism.

Fang R, Carroll RS, Kaiser UB

bioRxiv(2025)
Animal
PubMed

Activity Changes of the Hypothalamus-Pituitary Hormonal Axis in Peripubertal Female Rats.

Jeon EY, Lee SH

Dev Reprod(2025)
Animal
PubMed

Evidence for KISS-1 nuclear translocation and PI3K/AKT signaling in the ultrastructurally and morphometrically analyzed human endometriosis.

Hamutoğlu R, Kaloğlu C, Bulut HE et al.

Front Cell Dev Biol(2025)
Animal
PubMed

Therapeutic Effects of Phytoestrogen Naringenin in Polycystic Ovary Syndrome (PCOS): Involvement of Kisspeptin and Calcitonin Gene Related Peptide Signalling Pathways.

Habibi M, Mahmoudi F, Haghighat K et al.

Rep Biochem Mol Biol(2025)
Animal
PubMed

Tissue-Slice Organ-on-Chip Culture of Hypothalamic and Pituitary of Lambs─The Role of Phoenixin-20 as a Modulator of Gonadotrophic Axis.

Szlis M, Przybył BJ, Wójcik-Gładysz A

ACS Biomater Sci Eng(2026)
Animal
PubMed

Kisspeptin mediates the impact of chronic psychological stress on reproductive and metabolic dysregulation in polycystic ovary syndrome: evidence from human and rat models.

Mo T, Qiu Y, He S et al.

J Ovarian Res(2025)
Animal
PubMed

KNDy neurons as an indirect target of insulin-like growth factor-1.

Silva JDN, de Sousa LMM, de Sousa ME et al.

J Neuroendocrinol(2026)
Animal
GH ActivityNeuroprotection
PubMed

Citalopram-induced decrease of CLOCK-ir and BMAL1-ir kisspeptin neurons in the anteroventral periventricular nucleus of adult male mice.

Putteeraj M, Soga T, Parhar IS

IBRO Neurosci Rep(2025)
Animal
PubMed

Haploinsufficiency of Sox2 causes fewer GnRH neurons and delayed puberty in mice.

Cassin J, Dunn GA, Nguyen RD et al.

Endocrinology(2026)
Animal
Neuroprotection
PubMed

Kisspeptins inhibit ectopic endometrial cell invasion and angiogenesis by suppressing PI3K/AKT signaling pathway via CREB5 in endometriosis.

Kong L, Yushanjiang S, Nie L et al.

Int J Med Sci(2026)
Animal
PubMed

Inhibitory effects of a κ-opioid receptor agonist and neurokinin-3 receptor antagonist on testosterone secretion in male rats.

Sakono T, Munetomo A, Sato M et al.

Theriogenology(2026)
Animal
PubMed

Integrated transcriptomics and miRNA-mRNA network analysis reveals Kisspeptin-10 mediated regulation of EMT and apoptosis in glioblastoma.

Shah H, Mohan AM, Shah R et al.

Comput Biol Chem(2026)
Animal
PubMed

The Kisspeptin analogue C6 induces more synchronized ovulation than eCG in the transition period to breeding season in Corriedale ewes.

Bottino JP, Ungerfeld R, Taira AR et al.

Trop Anim Health Prod(2025)
Animal
PubMed

Dual role of Kisspeptin-10 in modulating neuroinflammation: Downregulation of NLRP3 inflammasome activation and Caspase-1-mediated pyroptosis, and activation of BAG3-dependent aggrephagy in microglial cells.

Kalkan ÖF, Erdem Ş, Erdem M et al.

Neuropeptides(2026)
Animal
PubMed

The protective effects of dapagliflozin on cisplatin-induced ovarian toxicity via NRF2-HO-1 pathway and TNF-α/Cas3 signaling.

Sarman E, Asci H, Selcuk E

Sci Rep(2025)
Animal
PubMed

Direct effect of kisspeptin on steroidogenesis, proliferation and apoptosis in Tan sheep ovarian granulosa cells.

Song W, Dai T, Yang D et al.

Zygote(2025)
Animal
PubMed
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