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INDEXED STUDIES

IGF-1 LR3 — Indexed Studies

43 most recent studies indexed by PSI from PubMed and clinical databases

Showing 43 of 43 studies

Differential effects of insulin-like growth factor-I and gonadotropins on the proliferative activity of two subgroups of granulosa cells: cumulus oophorus and mural granulosa cells.

Khamsi F, Roberge S

Fertil Steril(2001)
Human
GH Activity
PubMed

Provisional Treatment of Volumetric Muscle Loss With Insulin-like Growth Factor 1 Releasing Muscle Void Fillers.

Clark AR, Adams AT, McKinley TO et al.

J Surg Res(2026)
Animal
GH ActivityMuscle Recovery
PubMed

Revolutionary decellularized Alstroemeria stem-based nerve conduit integrated with GelMA and controlled IGF-1 LR3 release for enhanced rat sciatic nerve regeneration.

Yavuz E, Sağır MS, Ercan A et al.

Int J Biol Macromol(2025)
Animal
GH Activity
PubMed

IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep.

White A, Stremming J, Wesolowski SR et al.

Am J Physiol Endocrinol Metab(2025)
Animal
GH ActivityGlycemic Control
PubMed

Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.

Engel MG, Narayan S, Cui MH et al.

J Alzheimers Dis(2025)
Animal
GH ActivityCognitive Enhancement
PubMed

Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris.

Lu Z, Liu N, Huang H et al.

Appl Microbiol Biotechnol(2023)
Animal
GH Activity
PubMed

Attenuated glucose-stimulated insulin secretion during an acute IGF-1 LR3 infusion into fetal sheep does not persist in isolated islets.

White A, Stremming J, Brown LD et al.

J Dev Orig Health Dis(2023)
Animal
GH Activity
PubMed

N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling.

Salvi R, Kumar C, Brahmbhatt K et al.

Int J Mol Sci(2022)
Animal
GH Activity
PubMed

Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep.

Stremming J, White A, Donthi A et al.

Front Physiol(2022)
Animal
PubMed

Reduced glucose-stimulated insulin secretion following a 1-wk IGF-1 infusion in late gestation fetal sheep is due to an intrinsic islet defect.

White A, Stremming J, Boehmer BH et al.

Am J Physiol Endocrinol Metab(2021)
Animal
GH Activity
PubMed

IGF-1 infusion to fetal sheep increases organ growth but not by stimulating nutrient transfer to the fetus.

Stremming J, Heard S, White A et al.

Am J Physiol Endocrinol Metab(2021)
Animal
GH ActivityMuscle Recovery
PubMed

Coronary vascular growth matches IGF-1-stimulated cardiac growth in fetal sheep.

Jonker SS, Giraud GD, Chang EI et al.

FASEB J(2020)
Animal
GH Activity
PubMed

Inhibition of activin-like kinase 4/5 attenuates cancer cachexia associated muscle wasting.

Levolger S, Wiemer EAC, van Vugt JLA et al.

Sci Rep(2019)
Animal
Weight LossGH Activity
PubMed

Epidermal growth factor receptor is required for estradiol-stimulated bovine satellite cell proliferation.

Reiter BC, Kamanga-Sollo E, Pampusch MS et al.

Domest Anim Endocrinol(2014)
Animal
GH Activity
PubMed

Na+ transport across rumen epithelium of hay-fed sheep is acutely stimulated by the peptide IGF-1 in vitro.

Shen Z, Martens H, Schweigel-Röntgen M

Exp Physiol(2012)
Animal
GH Activity
PubMed

Potentiation of growth factor signaling by insulin-like growth factor-binding protein-3 in breast epithelial cells requires sphingosine kinase activity.

Martin JL, Lin MZ, McGowan EM et al.

J Biol Chem(2009)
Animal
GH Activity
PubMed

Enhancement of maternal lactation performance during prolonged lactation in the mouse by mouse GH and long-R3-IGF-I is linked to changes in mammary signaling and gene expression.

Hadsell DL, Parlow AF, Torres D et al.

J Endocrinol(2008)
Animal
GH Activity
PubMed

Effects of IGF-I bioavailability on bovine preantral follicular development in vitro.

Thomas FH, Campbell BK, Armstrong DG et al.

Reproduction(2007)
Animal
GH Activity
PubMed

Leptin in the bovine corpus luteum: receptor expression and effects on progesterone production.

Nicklin LT, Robinson RS, Marsters P et al.

Mol Reprod Dev(2007)
Animal
Liver Protection
PubMed

In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417.

Haluska P, Carboni JM, Loegering DA et al.

Cancer Res(2006)
Animal
GH Activity
PubMed

Enhanced response of granulosa and theca cells from sheep carriers of the FecB mutation in vitro to gonadotropins and bone morphogenic protein-2, -4, and -6.

Campbell BK, Souza CJ, Skinner AJ et al.

Endocrinology(2006)
Animal
GH Activity
PubMed

The local expression and abundance of insulin-like growth factor (IGF) binding proteins in skeletal muscle are regulated by age and gender but not local IGF-I in vivo.

Oliver WT, Rosenberger J, Lopez R et al.

Endocrinology(2005)
Animal
LongevityGH ActivityMuscle Recovery
PubMed

Interaction of bovine granulosa and theca cells in a novel serum-free co-culture system.

Allegrucci C, Hunter MG, Webb R et al.

Reproduction(2003)
Animal
GH Activity
PubMed

Extracellular signal-regulated kinase and phosphoinositol-3 kinase mediate IGF-1 induced proliferation of fetal sheep cardiomyocytes.

Sundgren NC, Giraud GD, Schultz JM et al.

Am J Physiol Regul Integr Comp Physiol(2003)
Animal
GH Activity
PubMed

Paracrine effects of oocyte secreted factors and stem cell factor on porcine granulosa and theca cells in vitro.

Brankin V, Mitchell MR, Webb B et al.

Reprod Biol Endocrinol(2003)
Animal
PubMed

Oocyte-mediated suppression of follicle-stimulating hormone- and insulin-like growth factor-induced secretion of steroids and inhibin-related proteins by bovine granulosa cells in vitro: possible role of transforming growth factor alpha.

Glister C, Groome NP, Knight PG

Biol Reprod(2003)
Animal
GH Activity
PubMed

IGF-I and IGFBP-3 transport in the rat heart.

Boes M, Dake BL, Booth BA et al.

Am J Physiol Endocrinol Metab(2003)
Animal
GH Activity
PubMed

Insulin-like growth factor-I and analogues increase growth in artificially-reared neonatal pigs.

Dunshea FR, Chung CS, Owens PC et al.

Br J Nutr(2002)
Animal
GH Activity
PubMed

Modulatory effects of gonadotrophins and insulin-like growth factor on the secretion of inhibin A and progesterone by granulosa cells from chicken preovulatory (F1-F3) follicles.

Lovell TM, Gladwell RT, Groome NP et al.

Reproduction(2002)
Animal
GH Activity
PubMed

Interactions between follicle-stimulating hormone and growth factors in modulating secretion of steroids and inhibin-related peptides by nonluteinized bovine granulosa cells.

Glister C, Tannetta DS, Groome NP et al.

Biol Reprod(2001)
Animal
GH Activity
PubMed

Granulosa cells of the cumulus oophorus are different from mural granulosa cells in their response to gonadotrophins and IGF-I.

Khamsi F, Roberge S

J Endocrinol(2001)
Animal
GH Activity
PubMed

Physicochemical characteristics of LR3-IGF1 protein inclusion bodies: electrophoretic mobility studies.

Wangsa-Wirawan ND, O'Neill BK, Middelberg AP

Biotechnol Prog(2001)
Animal
GH Activity
PubMed

The effect of insulin-like growth factor analogs on turkey satellite cell and embryonic myoblast proliferation.

Pesall JE, McFarland DC, McMurtry JP et al.

Poult Sci(2001)
Animal
GH ActivityMuscle Recovery
PubMed

Insulin-like growth factor I (IGF-I) and long R(3)IGF-I differently affect development and messenger ribonucleic acid abundance for IGF-binding proteins and type I IGF receptors in in vitro produced bovine embryos.

Prelle K, Stojkovic M, Boxhammer K et al.

Endocrinology(2001)
Animal
GH Activity
PubMed

Novel studies on influence of gonadotropins and insulin-like growth factor-I on growth of cumulus oophorus in the rat.

Khamsi F, Roberge S

Endocrine(2000)
Animal
GH Activity
PubMed

The modulation of gonadotrophic hormone action on the ovary by paracrine and autocrine factors.

Campbell BK

Anat Histol Embryol(1999)
Animal
PubMed

Clearance of IGFs and insulin from wounds: effect of IGF-binding protein interactions.

Robertson JG, Belford DA, Ballard FJ

Am J Physiol(1999)
Animal
GH Activity
PubMed

Effects of dose of LH on androgen production and luteinization of ovine theca cells cultured in a serum-free system.

Campbell BK, Baird DT, Webb R

J Reprod Fertil(1998)
Animal
GH Activity
PubMed

Interactions between follicle-stimulating hormone and growth factors in regulation of deoxyribonucleic acid synthesis in bovine granulosa cells.

Khamsi F, Armstrong DT

Biol Reprod(1997)
Animal
GH Activity
PubMed

The role of IGFBP-3 in the regulation of IGFBP-4 proteolysis.

Donnelly MJ, Holly JM

J Endocrinol(1996)
Animal
Tissue RemodelingGH ActivityWound Healing
PubMed

Effects of insulin and insulin-like growth factors on protein and energy metabolism in tumour-bearing rats.

Tomas FM, Chandler CS, Coyle P et al.

Biochem J(1994)
Animal
Glycemic ControlGH Activity
PubMed

Insulin-like growth factor-I and more potent variants restore growth of diabetic rats without inducing all characteristic insulin effects.

Tomas FM, Knowles SE, Owens PC et al.

Biochem J(1993)
Animal
GH Activity
PubMed

The role of insulin-like growth factors in small intestinal cell growth and development.

MacDonald RS

Horm Metab Res(1999)
Review
GH Activity
PubMed
Back to IGF-1 LR3 Research Overview

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