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INDEXED STUDIES

Humanin — Indexed Studies

50 most recent studies indexed by PSI from PubMed and clinical databases

Showing 50 of 50 studies

Nitrosative Stress, Mitochondrial Peptides, and Ferroptosis Markers in Corneal Epithelial Cells from Keratoconus Patients.

Demirkiran C, Mete A, Demiryürek AT et al.

Curr Eye Res(2026)
Human
PubMed

Exploring the therapeutic potential of MOTS-c in age-related macular degeneration: from cellular responses to patient-derived cybrids.

Mohtashami Z, Schneider K, Azimi R et al.

Hum Cell(2025)
Human
PubMed

Plasma Humanin and Non-Coding RNAs as Biomarkers of Endothelial Dysfunction in Rheumatoid Arthritis: A Pilot Study.

Coradduzza D, Cruciani S, Di Lorenzo B et al.

Noncoding RNA(2025)
Human
PubMed

Effects of empagliflozin and dapagliflozin on serum humanin, MOTS-c levels, nitrosative stress, and ferroptosis parameters in diabetic patients with heart failure.

Asil H, Demiryürek AT, Düzen IV et al.

Eur J Pharmacol(2024)
Human
Glycemic Control
PubMed

Unbalanced circulating Humanin levels and cardiovascular risk in chronic hemodialysis patients: a pilot, prospective study.

Bolignano D, Greco M, Presta P et al.

J Nephrol(2024)
Human
Cardiovascular Risk
PubMed

Comparative Analysis of Biomarkers in Type 2 Diabetes Patients With and Without Comorbidities: Insights Into the Role of Hypertension and Cardiovascular Disease.

Savvopoulos S, Hatzikirou H, Jelinek HF

Biomark Insights(2024)
Human
PubMed

Single cell transcriptomics of cerebrospinal fluid cells from patients with recent-onset narcolepsy.

Huth A, Ayoub I, Barateau L et al.

J Autoimmun(2024)
Human
PubMed

Impact of Radiation Therapy on Serum Humanin and MOTS-c Levels in Patients with Lung or Breast Cancer.

Kavak AG, Karslioglu I, Saracaloglu A et al.

Curr Radiopharm(2024)
Human
PubMed

Evaluation of Serum Humanin and MOTS-c Peptide Levels in Patients with COVID-19 and Healthy Subjects.

Saracaloglu A, Mete AÖ, Ucar DF et al.

Curr Protein Pept Sci(2023)
Human
PubMed

Humanin gene expression in subjects with Parkinson's disease.

Salemi M, Ridolfo F, Salluzzo MG et al.

Mol Biol Rep(2023)
Human
PubMed

Circulating humanin is lower in coronary artery disease and is a prognostic biomarker for major cardiac events in humans.

Cai H, Cao P, Sun W et al.

Biochim Biophys Acta Gen Subj(2022)
Human
Anti-Inflammatory
PubMed

Acute endurance exercise stimulates circulating levels of mitochondrial-derived peptides in humans.

von Walden F, Fernandez-Gonzalo R, Norrbom J et al.

J Appl Physiol (1985)(2021)
Human
Muscle Recovery
PubMed

Humanin regulates oxidative stress in the ovaries of polycystic ovary syndrome patients via the Keap1/Nrf2 pathway.

Wang Y, Li N, Zeng Z et al.

Mol Hum Reprod(2021)
Human
PubMed

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome.

Raijmakers RPH, Jansen AFM, Keijmel SP et al.

J Transl Med(2019)
Human
PubMed

[The level of circulating humanin in patients with ischemic heart disease.].

Zhloba AA, Subbotina TF, Molchan NS et al.

Klin Lab Diagn(2018)
Human
PubMed

Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans.

Yen K, Wan J, Mehta HH et al.

Sci Rep(2018)
Human
Cognitive EnhancementNeuroprotection
PubMed

Humanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage.

Nashine S, Cohen P, Chwa M et al.

Cell Death Dis(2017)
Human
PubMed

Neuroprotective Effect of Intraperitoneal Humanin-G in Retinal Degeneration of Royal College of Surgeons Rats.

Lin B, Schneider K, Ozgul M et al.

bioRxiv(2026)
Animal
PubMed

Mediterranean diet adherence is associated with mitochondrial microproteins Humanin and SHMOOSE; potential role of the Humanin-Nox2 interaction in cardioprotection.

Vicinanza R, Cammisotto V, Wan J et al.

Front Nutr(2025)
Animal
PubMed

Humanin as an evolutionarily tuned mitochondrial peptide: Insights from mammalian oxidative stress diversity.

Shahzaib M, Aprile D, Alessio N et al.

Free Radic Biol Med(2026)
Animal
PubMed

Characterization of the Effects of a Humanin Fragment Peptide (HNF(14)) in Age-Related Macular Degeneration.

Nashine S, Kenney MC

J Clin Med(2026)
Animal
PubMed

Mitochondrial-derived peptides MOTS-c and humanin attenuate dexamethasone-induced atrophy in human skeletal muscle cells.

Elhusseiny R, Ihsan M, Bellefroid T et al.

Physiol Rep(2026)
Animal
Muscle Recovery
PubMed

Mitochondrial derived peptide humanin improved semen quality, semen freezability, antioxidant status and in-vitro fertility in crossbred bull.

Gemeda AE, Singh M, Katiyar R et al.

Sci Rep(2026)
Animal
PubMed

Humanin improves bone health in a glucocorticoid-treated mouse model of Duchenne muscular dystrophy.

Cedervall T, Jude B, von Walden F et al.

Biochem Biophys Rep(2026)
Animal
PubMed

Diagnostic potential of serum humanin in breast cancer among the Egyptian population.

Mohamed MH, Kamel WT, Ibrahim EH et al.

Discov Oncol(2026)
Animal
PubMed

SHLP2 restores pre-osteoblastic cells against oxidative stress-induced inflammaging.

Ryu JH, Mangal U, Kim JH et al.

Sci Rep(2025)
Animal
PubMed

Insights into the Biomarker Potential of Humanin and Mots-c Expression and Telomere Length in Alzheimer's Disease.

Rodríguez-Esparragón F, Cazorla-Rivero SE, Torrealba E et al.

Int J Mol Sci(2025)
Animal
Longevity
PubMed

Herkinorin Promotes μ-Opioid Receptor Internalization and Protects iPSC-Derived Neurons from Hypoxic/Ischemic Injury.

Ju Z, Wang G, Yan Y et al.

J Integr Neurosci(2025)
Animal
Neuroprotection
PubMed

Assessment of mitochondrial peptide humanin in women with polycystic ovary syndrome: serum and skeletal muscle profile.

Kutuk IS, Akin S, Demirel H et al.

J Endocrinol Invest(2026)
Animal
PubMed

Hierarchical random forest model, inflammation and oxidative stress as predictors of the atherogenic index of plasma and diabetes progression.

Jelinek HF, Muteir I, Al-Aubaidy H

Sci Rep(2025)
Animal
Glycemic ControlAnti-InflammatoryCardiovascular Risk
PubMed

Exercise Improves Cardiac Dysfunction in D-Galactose-Treated Rats by Regulation of IGF-1-Humanin Pathway.

Askarimoghadam H, Rostamzadeh F, Mirtajaddini Goki M et al.

J Aging Res(2025)
Animal
PubMed

In-silico modeling of SHLP6: A novel mitochondrial peptide controlling neurodegeneration and cellular aging.

Kannan HT, Umapathy S, Pan I

Comput Biol Med(2025)
Animal
PubMed

HUMANIN produced by human efferocytic macrophages promotes the resolution of inflammation.

Maraux M, Vetter M, Zuffo LD et al.

Cell Death Dis(2025)
Animal
Anti-Inflammatory
PubMed

Detection of Mitochondrial-Derived Peptide Humanin in Semen and Reproductive Tract of Caprine Along With Its Relation to Seasonality.

Chouksey S, Shukla SN, Dubey A et al.

Reprod Domest Anim(2025)
Animal
PubMed

S14G-Humanin ameliorates ovarian dysfunction in a cyclophosphamide-induced premature ovarian insufficiency mouse model.

Huang J, Zhang D, Zou L et al.

Mol Hum Reprod(2025)
Animal
PubMed

Diagnostic relevance of Humanin, GAS5 and miR-21/miR-103 in prostate disease risk stratification.

Coradduzza D, Cruciani S, Sibono L et al.

Clin Exp Med(2025)
Animal
PubMed

Ameliorative effects of Gly[14]-humanin on cyclophosphamide-induced premature ovarian insufficiency and underlying mechanisms.

Huang J, Liu Y, Zou L et al.

Reprod Biomed Online(2025)
Animal
PubMed

SHLP6: a novel NLRP3 and Cav1 modulating agent in Cu-induced oxidative stress and neurodegeneration.

Thamarai Kannan H, Umapathy S, Pan I

Front Mol Neurosci(2025)
Animal
PubMed

Humanin reduces nucleus pulposus cells ferroptosis to alleviate intervertebral disc degeneration: An in vitro and in vivo study.

Zhu D, Wang Z, Li Y et al.

J Orthop Translat(2025)
Animal
PubMed

Humanin alone and in combination with GnRHa therapy attenuates ovarian dysfunction induced by prepubertal cyclophosphamide chemotherapy in female mice.

Liu L, Wang H, Wen W et al.

Reprod Toxicol(2025)
Animal
PubMed

[Gly14]-Humanin ameliorates high glucose-induced endothelial senescence via SIRT6.

Li M, Liu Z, Cao X et al.

Sci Rep(2024)
Animal
Longevity
PubMed

Humanin-G Ameliorates Hemorrhage-Induced Acute Lung Injury in Mice Through AMPKα1-Dependent and -Independent Mechanisms.

Amman AM, Wolfe V, Piraino G et al.

Biomedicines(2024)
Animal
PubMed

Humanin attenuates metabolic, toxic, and traumatic neuropathic pain in mice by protecting against oxidative stress and increasing inflammatory cytokine.

Bilgin B, Hekim MG, Bulut F et al.

Neuropharmacology(2025)
Animal
Anti-Inflammatory
PubMed

Mitochondrial-derived peptides, HNG and SHLP3, protect cochlear hair cells against gentamicin.

Lu Y, Bartoszek EM, Cortada M et al.

Cell Death Discov(2024)
Animal
PubMed

Quantitative proteomics analysis reveals the protective role of S14G-humanin in septic acute kidney injury using 4D-label-free and PRM Approaches.

Shi Q, Xiao Z, Cai W et al.

Biochem Biophys Res Commun(2024)
Animal
PubMed

Temporal expression of mitochondrial life cycle markers during acute and chronic overload of rat plantaris muscles.

Hyatt JK, Lu EJ, McCall GE

Front Physiol(2024)
Animal
PubMed

Rational fusion design inspired by cell-penetrating peptide: SS31/S-14 G Humanin hybrid peptide with amplified multimodal efficacy and bio-permeability for the treatment of Alzheimer's disease.

Qian K, Yang P, Li Y et al.

Asian J Pharm Sci(2024)
Animal
PubMed

Effect of Humanin and MOTS-c on ameliorating reproductive damage induced by prepubertal cyclophosphamide chemotherapy in male mice.

Wang J, Wen W, Liu L et al.

Reprod Toxicol(2024)
Animal
PubMed

Humanin activates integrin αV-TGFβ axis and leads to glioblastoma progression.

Ha CP, Hua TNM, Vo VTA et al.

Cell Death Dis(2024)
Animal
PubMed

Humanin P3S, haplogroup N1b and the risk of Alzheimer's disease.

Logan IS

Aging Cell(2024)
Animal
PubMed
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