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INDEXED STUDIES

GHK-Cu — Indexed Studies

50 most recent studies indexed by PSI from PubMed and clinical databases

Showing 50 of 50 studies

Combination Tripeptide/Hexapeptide Serum with 1540 nm Nonablative Fractional Laser for the Treatment of Striae Distensae: A Pilot Study.

McGuinn KP, Ross NA, Wang JV et al.

Skinmed(2020)
Human
PubMed

Evaluation of the effects of topical tripeptide-copper complex and zinc oxide on open-wound healing in rabbits.

Cangul IT, Gul NY, Topal A et al.

Vet Dermatol(2006)
Human
Wound Healing
PubMed

Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin.

Miller TR, Wagner JD, Baack BR et al.

Arch Facial Plast Surg(2006)
Human
Wound Healing
PubMed

A prospective randomized evaluator-blinded trial of two potential wound healing agents for the treatment of venous stasis ulcers.

Bishop JB, Phillips LG, Mustoe TA et al.

J Vasc Surg(1992)
Human
Wound Healing
PubMed

Golgi-targeted copper delivery strategy via enhancing copper-dependent proteins' activity for fascia regeneration.

Wang R, Xu Y, Saiding Q et al.

J Control Release(2026)
Animal
Tissue Remodeling
PubMed

An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant.

Hu D, Zhang X, Gong S et al.

Colloids Surf B Biointerfaces(2025)
Animal
Anti-Inflammatory
PubMed

Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms.

Mao S, Huang J, Li J et al.

Front Pharmacol(2025)
Animal
PubMed

Interaction of half-sandwich Rh(III) ion and some of its complexes with endogenous imidazole derivatives.

Hassoon AA, Szorcsik A, Gajda T

J Inorg Biochem(2025)
Animal
PubMed

Intrinsically photoluminescent hydrogels to measure peptides‑copper binding affinities.

Distefano A, Corsaro P, Tuccitto N et al.

J Inorg Biochem(2025)
Animal
PubMed

Copper Complexes with New Glycyl-l-histidyl-l-lysine-Hyaluronan Conjugates Show Antioxidant Properties and Osteogenic and Angiogenic Synergistic Effects.

Greco V, Lanza V, Tomasello B et al.

Bioconjug Chem(2025)
Animal
Tissue Remodeling
PubMed

Self-Assembled Peptide-Gold Nanoparticle 1D Nanohybrids Functionalized with GHK Tripeptide for Enhanced Wound-Healing and Photothermal Therapy.

Jeon N, Kim L, Choi SG et al.

ACS Appl Mater Interfaces(2025)
Animal
Wound Healing
PubMed

Nanoengineered Self-Assembling Peptides with Increased Proteolytic Stability Promote Wound Healing.

Castro VIB, Araújo AR, Reis RL et al.

ACS Appl Mater Interfaces(2025)
Animal
Wound Healing
PubMed

Food-Derived Tripeptide-Copper Self-Healing Hydrogel for Infected Wound Healing.

Chen H, Yang P, Xue P et al.

Biomater Res(2025)
Animal
PubMed

Palmitoyl copper peptide and acetyl tyrosine complex enhances melanin production in both A375 and B16 cell lines.

Hong M, Gui Y, Xu J et al.

Biochem Biophys Res Commun(2025)
Animal
PubMed

Novel Applications of CE-ICP-MS/MS: Monitoring of Antiaging GHK-Cu Cosmetic Component Encapsulation in Liposomes.

Zajda J, Wadych E, Ogórek K et al.

Electrophoresis(2024)
Animal
Skin & Cosmetic
PubMed

The glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6.

Bian Y, Deng M, Liu J et al.

Redox Biol(2024)
Animal
PubMed

Glycyl-l-histidyl-l-lysine prevents copper- and zinc-induced protein aggregation and central nervous system cell death in vitro.

Min JH, Sarlus H, Harris RA

Metallomics(2024)
Animal
Neuroprotection
PubMed

Rigid-flexible nanocarriers loaded with active peptides for antioxidant and anti-inflammatory applications in skin.

Wang Y, Lin J, Yu Z et al.

Colloids Surf B Biointerfaces(2024)
Animal
Wound HealingAnti-Inflammatory
PubMed

Effects of Gly-His-Lys-D-Ala Peptide on Skin Wound Regeneration Processes.

Rakhmetova KK, Mishina ES, Bobyntsev II et al.

Bull Exp Biol Med(2024)
Animal
PubMed

Behavioral and neuropathological features of Alzheimer's disease are attenuated in 5xFAD mice treated with intranasal GHK peptide.

Tucker M, Liao GY, Keely A et al.

Aging Pathobiol Ther(2024)
Animal
PubMed

Behavioral and neuropathological features of Alzheimer's disease are attenuated in 5xFAD mice treated with intranasal GHK peptide.

Tucker M, Liao GY, Park JY et al.

bioRxiv(2023)
Animal
PubMed

Thermodynamically stable ionic liquid microemulsions pioneer pathways for topical delivery and peptide application.

Liu T, Liu Y, Zhao X et al.

Bioact Mater(2024)
Animal
PubMed

Intranasal GHK peptide enhances resilience to cognitive decline in aging mice.

Tucker M, Keely A, Park JY et al.

bioRxiv(2023)
Animal
PubMed

Liposomes as Carriers of GHK-Cu Tripeptide for Cosmetic Application.

Dymek M, Olechowska K, Hąc-Wydro K et al.

Pharmaceutics(2023)
Animal
PubMed

In situ photo-crosslinkable hyaluronic acid-based hydrogel embedded with GHK peptide nanofibers for bioactive wound healing.

Lee S, Lee SM, Lee SH et al.

Acta Biomater(2023)
Animal
Wound HealingTissue Remodeling
PubMed

Phenothiazine-Based Cu(II)-Selective Fluorescent Sensor: GHK-Cu Sensing Applications.

Sahu R, Yadav S, Gunturu KC et al.

J Org Chem(2023)
Animal
PubMed

New Biotinylated GHK and Related Copper(II) Complex: Antioxidant and Antiglycant Properties In Vitro against Neurodegenerative Disorders.

Tosto R, Vecchio G, Bellia F

Molecules(2023)
Animal
PubMed

Ultrasensitive and Label-Free Detection of Copper Ions by GHK-Modified Asymmetric Nanochannels.

An P, Zhang Z, Yang J et al.

Anal Chem(2023)
Animal
PubMed

Multi working mode SPR chip laboratory for high refractive index detection.

Ren Z, Liu C, Wei Y et al.

Opt Express(2023)
Animal
PubMed

Relief of ovalbumin-induced airway remodeling by the glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex via activation of SIRT1 in airway epithelial cells.

Zhang Q, Liu J, Deng MM et al.

Biomed Pharmacother(2023)
Animal
PubMed

Improved laccase production by Trametes versicolor using Copper-Glycyl-L-Histidyl-L-Lysine as a novel and high-efficient inducer.

Wang F, Yu X, Yu Z et al.

Front Bioeng Biotechnol(2023)
Animal
PubMed

Differential Effects of Histidine and Histidinamide versus Cysteine and Cysteinamide on Copper Ion-Induced Oxidative Stress and Cytotoxicity in HaCaT Keratinocytes.

Ha JW, Choi JY, Boo YC

Antioxidants (Basel)(2023)
Animal
PubMed

Synergy of GHK-Cu and hyaluronic acid on collagen IV upregulation via fibroblast and ex-vivo skin tests.

Jiang F, Wu Y, Liu Z et al.

J Cosmet Dermatol(2023)
Animal
Tissue Remodeling
PubMed

Glycyl-l-histidyl-l-lysine-Cu(2+) rescues cigarette smoking-induced skeletal muscle dysfunction via a sirtuin 1-dependent pathway.

Deng M, Zhang Q, Yan L et al.

J Cachexia Sarcopenia Muscle(2023)
Animal
Muscle Recovery
PubMed

Structural basis for lipid and copper regulation of the ABC transporter MsbA.

Lyu J, Liu C, Zhang T et al.

Nat Commun(2022)
Animal
PubMed

Glycyl-L-histidyl-L-lysine-Cu(2+) attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway.

Zhang Q, Yan L, Lu J et al.

Front Mol Biosci(2022)
Animal
PubMed

Biomimetic Hydrogel Scaffolds with Copper Peptide-Functionalized RADA16 Nanofiber Improve Wound Healing in Diabetes.

Yang X, Zhang Y, Huang C et al.

Macromol Biosci(2022)
Animal
Wound Healing
PubMed

Polyaspartic acid, 2-acrylamido-2-Methyl propane sulfonic acid and sodium alginate based biocompatible stimuli responsive polymer gel for controlled release of GHK-Cu peptide for wound healing.

Sharma S, Anwar MF, Dinda AK et al.

J Biomater Appl(2022)
Animal
Wound Healing
PubMed

Intermediate Cu(II)-Thiolate Species in the Reduction of Cu(II)GHK by Glutathione: A Handy Chelate for Biological Cu(II) Reduction.

Ufnalska I, Drew SC, Zhukov I et al.

Inorg Chem(2021)
Animal
PubMed

Efficient Ternary Polymer Solar Cells with Tunable Crystallinity and Phase Separation of Active Layers via Incorporating GHK-Cu.

Huang J, Yu H

ACS Appl Mater Interfaces(2021)
Animal
PubMed

Ergothioneine in a peptide: Substitution of histidine with 2-thiohistidine in bioactive peptides.

Jenny KA, Ruggles EL, Liptak MD et al.

J Pept Sci(2021)
Animal
PubMed

Measurement of Interpeptidic Cu(II) Exchange Rate Constants of Cu(II)-Amyloid-β Complexes to Small Peptide Motifs by Tryptophan Fluorescence Quenching.

Beuning CN, Zocchi LJ, Malikidogo KP et al.

Inorg Chem(2021)
Animal
PubMed

Protective and Anti-Aging Effects of 5 Cosmeceutical Peptide Mixtures on Hydrogen Peroxide-Induced Premature Senescence in Human Skin Fibroblasts.

Wu Y, Cao K, Zhang W et al.

Skin Pharmacol Physiol(2021)
Animal
Tissue RemodelingSkin & Cosmetic
PubMed

Enhanced angiogenic effects of RGD, GHK peptides and copper (II) compositions in synthetic cryogel ECM model.

Zoughaib M, Luong D, Garifullin R et al.

Mater Sci Eng C Mater Biol Appl(2021)
Animal
Wound Healing
PubMed

The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography.

Mehr A, Henneberg F, Chari A et al.

Acta Crystallogr D Struct Biol(2020)
Animal
PubMed

Hydrogels based on low-methoxyl amidated citrus pectin and flaxseed gum formulated with tripeptide glycyl-l-histidyl-l-lysine improve the healing of experimental cutting wounds in rats.

Synytsya A, Poučková P, Zadinová M et al.

Int J Biol Macromol(2020)
Animal
Wound Healing
PubMed

Ternary Cu(II) Complex with GHK Peptide and Cis-Urocanic Acid as a Potential Physiologically Functional Copper Chelate.

Bossak-Ahmad K, Wiśniewska MD, Bal W et al.

Int J Mol Sci(2020)
Animal
PubMed

Expression and Purification of Recombinant GHK Tripeptides Are Able to Protect against Acute Cardiotoxicity from Exposure to Waterborne-Copper in Zebrafish.

Hsiao CD, Wu HH, Malhotra N et al.

Biomolecules(2020)
Animal
PubMed

Coassemble dopamine and GHK tripeptide into fluorescent nanoparticles for pH sensing.

Zheng F, Guo J, Khan AJ et al.

Luminescence(2021)
Animal
Neuroprotection
PubMed

Theoretical study of copper binding to GHK peptide.

Alshammari N, Platts JA

Comput Biol Chem(2020)
Animal
PubMed
Back to GHK-Cu Research Overview

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