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INDEXED STUDIES

FOXO4-DRI — Indexed Studies

11 most recent studies indexed by PSI from PubMed and clinical databases

Showing 11 of 11 studies

FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway.

Hu Z, Li F, Hu C et al.

Front Bioeng Biotechnol(2025)
Animal
PubMed

The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI.

Bourgeois B, Spreitzer E, Platero-Rochart D et al.

Nat Commun(2025)
Animal
Longevity
PubMed

FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation.

Kong YX, Li ZS, Liu YB et al.

Commun Biol(2025)
Animal
Tissue RemodelingLongevity
PubMed

FOXO4-D-Retro-Inverso targets extracellular matrix production in fibroblasts and ameliorates bleomycin-induced pulmonary fibrosis in mice.

Liu Y, Hou Q, Wang R et al.

Naunyn Schmiedebergs Arch Pharmacol(2023)
Animal
Tissue Remodeling
PubMed

Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression.

Born E, Lipskaia L, Breau M et al.

Circulation(2023)
Animal
PubMed

FOXO4 peptide targets myofibroblast ameliorates bleomycin-induced pulmonary fibrosis in mice through ECM-receptor interaction pathway.

Han X, Yuan T, Zhang J et al.

J Cell Mol Med(2022)
Animal
PubMed

Targeting senescence-like fibroblasts radiosensitizes non-small cell lung cancer and reduces radiation-induced pulmonary fibrosis.

Meng J, Li Y, Wan C et al.

JCI Insight(2021)
Animal
LongevityTissue Remodeling
PubMed

Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes.

Huang Y, He Y, Makarcyzk MJ et al.

Front Bioeng Biotechnol(2021)
Animal
PubMed

Rejuvenation by Therapeutic Elimination of Senescent Cells.

Krimpenfort P, Berns A

Cell(2017)
Animal
PubMed

Cellular senescence in the aging and diseased kidney.

Valentijn FA, Falke LL, Nguyen TQ et al.

J Cell Commun Signal(2018)
Review
PubMed

[Molecular regulative mechanisms of aging and interventional effects of Chinese herbal medicine].

Liu BH, Gu YH, Tu Y et al.

Zhongguo Zhong Yao Za Zhi(2017)
Review
Longevity
PubMed
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