Research Index
Follistatin Research Index
PSI surfaces 50 peer-reviewed studies on Follistatin, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
50 studies
High Expression of Follistatin is a Risk Factor Predicting Poor Overall Survival in Hepatocellular Carcinoma Patients.
Dai Y, Pan B, Zhao J et al.
J Hepatocell Carcinoma·2026·Human·PubMed →
Dysregulation of adipokines in the serum of breast cancer patients - role in pathogenesis and potential clinical application (preliminary studies).
Morawiec ML, Wendlocha D, Kabut J et al.
Front Immunol·2026·Human·PubMed →
Leptin/Adiponectin Ratio as a new multidimensional biomarker in obese patients with liver steatosis undergoing VLEKT: results from a pilot study.
Balestra F, Donghia R, De Luca M et al.
Front Nutr·2026·Human·PubMed →
Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial.
Jeong D, Valentine RJ, Jeong H et al.
J Int Soc Sports Nutr·2026·Human·Muscle Recovery, Anti-Inflammatory·PubMed →
Higher serum follistatin levels are associated with increased vascular calcification in haemodialysis patients.
Liu C, Zhang A, Li Z
Front Endocrinol (Lausanne)·2026·Human·PubMed →
Adipo-Myokine Modulation in Obesity: Integrative Effects of Spinach Thylakoids and Functional Training in Men with Obesity: A Randomized Controlled Clinical Trial.
Razi O, Shafei A, Abdi M et al.
Nutrients·2026·Human·Weight Loss, Glycemic Control·PubMed →
Lorcaserin induces abdominal fat loss with associated improvements of the circulating metabolome/lipidome and no changes in the myostatin-activin-follistatin-IGF-1 axes: A 6-month long randomized placebo-controlled clinical trial.
Ramirez-Cisneros A, Gutierrez de Piñeres V, Tamayo-Torres CS et al.
Diabetes Obes Metab·2026·Human·Weight Loss, GH Activity·PubMed →
Effects of liraglutide treatment for 35-days on total and regional fat free, lean, and bone mass, and on the Myostatin-Activin-Follistatin-IGF-1 axes: a secondary analysis of a randomized placebo-controlled crossover study.
Gutierrez de Piñeres V, Ramirez-Cisneros A, Tamayo-Torres CS et al.
Diabetes Res Clin Pract·2026·Human·Weight Loss, GH Activity, Bone Healing·PubMed →
Effects of liraglutide treatment for 18 days on metabolic parameters, regional body composition and the myostatin-activin-follistatin-IGF-1 axis: Results from an exploratory, randomized, placebo-controlled, crossover study.
Gutierrez de Piñeres V, Tamayo-Torres CS, Ramirez-Cisneros A et al.
Diabetes Obes Metab·2026·Human·Glycemic Control, GH Activity·PubMed →
miR-769-5p inhibits cellular behaviors associated with endometriosis progression by directly targeting follistatin in vitro.
Meng Y, Chen Q, Lu H
Nucleosides Nucleotides Nucleic Acids·2026·Animal·PubMed →
Detection of Activin A and Follistatin as Potential Biomarkers in Women with Ovarian Endometriosis.
Makki NF, Kadhum SH
J Steroid Biochem Mol Biol·2026·Animal·PubMed →
FSTL3-Driven Cuproptosis Resistance and EPCs Promote OSCC Metastasis.
Li SR, Wu ZZ, Wang WD et al.
J Dent Res·2026·Animal·PubMed →
Molecular and endocrine differences in early miscarriage associated with KIR polymorphisms in European ancestry women.
Cuadrado-Torroglosa I, Palomar A, Quiñonero A et al.
Reprod Biomed Online·2026·Animal·PubMed →
Screening performance of a lifestyle-based questionnaire score for vitamin D deficiency and related functional and physiological characteristics in older women.
Jeong H, Jeong D, Kang S
Phys Act Nutr·2026·Animal·PubMed →
Piezo1-Fstl1 Axis in Fracture Healing: Modulation of the Chondrocyte Inflammation-ROS-Mitochondrial Damage Cascade and Application of Smart Delivery System.
Zhang T, Wang H, Hou G et al.
Int J Biol Sci·2026·Animal·Anti-Inflammatory·PubMed →
Follistatin-like protein 1 (FSTL1) modulates bone remodeling and attenuates bone loss in a mouse model of postmenopausal osteoporosis.
Yuan H, Chen BR, Han FX et al.
JBMR Plus·2026·Animal·PubMed →
Activin A-Endothelin-1 Axis Governs Pulmonary Vascular Remodeling: Mechanistic Basis for Emerging Therapies in PAH.
Faizah NN, Ryanto GRT, Kencana SMS et al.
Arterioscler Thromb Vasc Biol·2026·Animal·PubMed →
Diagnostic Performance of Serum Adiponectin and a Biomarker-Based Model for Sarcopenia in Compensated Cirrhosis.
Boonpiraks K, Thaweesukolrat P, Surinlert P et al.
J Clin Exp Hepatol·2026·Animal·PubMed →
Endogenous targeting lipid nanoparticles for systemic mRNA delivery to lung cancer tumors.
Goo YT, Grigoriev V, Korzun T et al.
J Control Release·2026·Animal·PubMed →
The Role of Follistatin-like 1 in the Cross-Talk Among Osteoclastogenesis, Bone Marrow Stromal Cell Migration, and Osteoblastogenesis In Vitro.
Piao Y, Che X, Jin X et al.
Biomedicines·2026·Animal·PubMed →
Puerarin alleviates diabetic atherosclerosis through controlling the follistatin-like 1 related inflammation.
Chen J, Hu Z, Fang M et al.
Coron Artery Dis·2026·Animal·Cardiovascular Risk, Anti-Inflammatory·PubMed →
Cinnamaldehyde Regulates the EMT Process and Drug Resistance of Gastric Cancer Through FSTL3-Mediated Cytoskeletal Remodeling.
Zeng S, Yin Y, Zhang Y et al.
Phytother Res·2026·Animal·PubMed →
Canonical WNT signalling governs Echinococcus metacestode development.
Herrmann R, Herz M, Rudolf K et al.
PLoS Pathog·2026·Animal·PubMed →
Circulating plasma follistatin follows a 24-hour rhythm in healthy young males.
Zilstorff DB, Sennels HP, Jørgensen HL et al.
J Clin Endocrinol Metab·2026·Animal·PubMed →
[Baicalin ameliorates obesity-related lung injury by targeting FSTL1/DIP2A signaling pathway].
Cui PL, Qi BX, Wu MD et al.
Zhongguo Zhong Yao Za Zhi·2026·Animal·Weight Loss·PubMed →
Spinal cord injury-induced overflow incontinence reshapes the activin-follistatin-inhibin axis in mouse bladder and kidney.
Shen Y, Yang S, Zhou H et al.
Front Mol Biosci·2026·Animal·PubMed →
Targeted delivery of Follistatin-like 1 siRNA via biodegradable nanoparticles attenuates bleomycin-induced pulmonary fibrosis in mice.
Li X, Yao M, Yu M et al.
Exp Lung Res·2026·Animal·Tissue Remodeling·PubMed →
Multimodal characterization of sustained bioagent release from an epicardial depot for long-term biomaterial incorporation.
Varela CE, Monahan DS, Fan Y et al.
Biomaterials·2026·Animal·PubMed →
Assessing Aβ-independent effects of Module 42 on immune function in vitro.
Ajith I, Bakshi S, Mead E et al.
Alzheimers Dement·2026·Animal·PubMed →
Obese adipocytes induce fibroblast-to-myofibroblast transition through TGF-β1 signaling: implications in asthma pathogenesis.
Jalaleddine N, Hachim M, Giddey A et al.
Am J Physiol Lung Cell Mol Physiol·2026·Animal·Weight Loss, Tissue Remodeling·PubMed →
FSTL1 promotes dendritic cell pyroptosis and immunosuppression in sepsis by inhibiting STING autophagy.
Li Q, Ling H, Li J et al.
PLoS One·2026·Animal·PubMed →
Circulating Activin A and Follistatin-like Proteins in Rheumatoid Arthritis with Interstitial Lung Disease: A Cross-Sectional Comparative Study.
Ulutaş F, Kaya K, Yiğit N et al.
Diagnostics (Basel)·2026·Animal·PubMed →
Polygonatum cyrtonema Hua fructan ameliorates ulcerative colitis via gut microbiota modulation and follistatin targeting.
Xu Q, Lv Q, Yang Z et al.
NPJ Sci Food·2026·Animal·PubMed →
Serum FSTL-1 and AI-assessed muscle parameters in cancer-related malnutrition.
de Luis D, Primo D, Izaola O et al.
Nutrition·2026·Animal·Muscle Recovery·PubMed →
FSTL1 contribute to aggressive clinical behavior in DLBCL may by activating the DIP2A/ICAM-1-mediated adhesion mechanism.
Liang X, Zhang X, Wang C et al.
Biomed Pharmacother·2026·Animal·PubMed →
Cardiac rehabilitation influences serum myokine levels in patients after acute coronary syndrome: the randomised CARDIO-REH study.
Skrypnik D, Skrypnik K, Granell JC et al.
Sci Rep·2025·Human·PubMed →
The Role of Selected Myokines in the Development of Cardiovascular Diseases, and Their Involvement in Developing Heart Failure in Rheumatoid Arthritis Patients.
Kuna J, Chmielewski G, Jaśkiewicz Ł et al.
Int J Mol Sci·2025·Human·Cardiovascular Risk, Anti-Inflammatory·PubMed →
Plasma FSTL-1 as a noninvasive diagnostic biomarker for patients with advanced liver fibrosis.
Li W, Chi Y, Xiao X et al.
Hepatology·2025·Human·Liver Protection·PubMed →
Dynamic changes of systemic and local myokines in burn patients undergoing physiotherapy: A pilot prospective study.
Svecova M, Bakalar B, Vyklicka K et al.
Burns·2025·Human·Wound Healing, Muscle Recovery·PubMed →
Exploratory unsupervised machine learning of angiogenesis biomarkers in a phase II advanced cervical cancer trial of radiochemotherapy with or without neoadjuvant chemotherapy.
Arai RJ, da Costa TR, Bonadio RC et al.
Clinics (Sao Paulo)·2025·Human·PubMed →
FST Polymorphisms Associate with Musculoskeletal Traits and Modulate Exercise Response Differentially by Sex and Modality in Northern Han Chinese Adults.
Cao W, Gu Z, Fu R et al.
Genes (Basel)·2025·Human·Muscle Recovery·PubMed →
Changes in serum myostatin levels among patients with type C liver cirrhosis treated with direct-acting antivirals.
Suehiro T, Kozuru H, Matusmoto K et al.
Hepatol Res·2025·Human·PubMed →
Effects of 12-week whole-body vibration training versus resistance training in older people with sarcopenia.
Zhuang M, Gu Y, Wang Z et al.
Sci Rep·2025·Human·Muscle Recovery, Weight Loss·PubMed →
The Effect of Exercise on Spexin and Follistatin in Elderly Individuals.
Ayaz EY, Dincer B, Cinbaz G et al.
J Cachexia Sarcopenia Muscle·2025·Human·PubMed →
A first-in-human study of JNJ-70218902, a bispecific T-cell-redirecting antibody against TMEFF2 in metastatic castration-resistant prostate cancer.
Calvo E, Doger B, Carles J et al.
Oncologist·2025·Human·Immune Modulation·PubMed →
Effects of Resistance Training on Muscular Adaptations and Inflammatory Markers in Overweight and Obese Men.
Bagheri N, Bagheri R, Mesinovic J et al.
Med Sci Sports Exerc·2025·Human·Anti-Inflammatory, Muscle Recovery, Weight Loss·PubMed →
Pasteurized Akkermansia muciniphila HB05 (HB05P) Improves Muscle Strength and Function: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Kang CH, Jung ES, Jung SJ et al.
Nutrients·2024·Human·Muscle Recovery·PubMed →
Effectiveness of low-load resistance training with blood flow restriction vs. conventional high-intensity resistance training in older people diagnosed with sarcopenia: a randomized controlled trial.
Zhang M, Song Y, Zhu J et al.
Sci Rep·2024·Human·Muscle Recovery·PubMed →
Supplementing With Which Form of Creatine (Hydrochloride or Monohydrate) Alongside Resistance Training Can Have More Impacts on Anabolic/Catabolic Hormones, Strength and Body Composition?
Eghbali E, Arazi H, Suzuki K
Physiol Res·2024·Human·GH Activity, Muscle Recovery·PubMed →
Exploring the Impact of Astaxanthin Supplementation in Conjunction with a 12-Week CrossFit Training Regimen on Selected Adipo-Myokines Levels in Obese Males.
Moqaddam MA, Nemati M, Dara MM et al.
Nutrients·2024·Human·Weight Loss, Glycemic Control·PubMed →