Research Index
Follistatin Research Index
PSI surfaces 50 peer-reviewed studies on Follistatin, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.
50 studies
Changes in the concentration of new adipokines in serum and peritoneal fluid of patients with serous ovarian cancer as a target for potential use in new diagnostic and therapeutic strategies.
Stepien S, Smycz-Kubanska M, Wikarek A et al.
Ginekol Pol·2026·Human·PubMed →
Novel cardiac biomarkers (serum S100A12 (Calgranulin C), FSTL1 (Follistatin-like 1), and osteocalcin) in patients with acute chest pain.
Xie W, Zhao W, Wang H et al.
J Med Biochem·2026·Human·PubMed →
Follistatin and Systolic Function at Follow-Up in STEMI Patients: A Cardiac Magnetic Resonance Study.
Gavara J, Molina-García T, de Dios E et al.
J Clin Med·2026·Human·PubMed →
A Single-Food Substitution Strategy (SFSS) Improves Fat Mass and Metabolic Parameters in MASLD: A Prospective Pilot Study.
Cerabino N, Bonfiglio C, Bonfrate L et al.
Nutrients·2026·Human·Liver Fat (MASLD), Weight Loss·PubMed →
Adverse Hemodynamics in Acute Heart Failure Patients Are Associated with Skeletal Muscle Stress Biomarkers.
Kobak KA, Kasztura M, Josiak K et al.
Int J Mol Sci·2026·Human·Muscle Recovery·PubMed →
Elevated Circulating Follistatin Is Associated With Diabetic Status and Glycemic Dysregulation in Patients With β-Thalassemia Major.
Taneera J, Mohammed AK, Shaireh HMAA et al.
Cell Biochem Funct·2026·Human·Glycemic Control·PubMed →
High Expression of Follistatin is a Risk Factor Predicting Poor Overall Survival in Hepatocellular Carcinoma Patients.
Dai Y, Pan B, Zhao J et al.
J Hepatocell Carcinoma·2026·Human·PubMed →
Dysregulation of adipokines in the serum of breast cancer patients - role in pathogenesis and potential clinical application (preliminary studies).
Morawiec ML, Wendlocha D, Kabut J et al.
Front Immunol·2026·Human·PubMed →
Leptin/Adiponectin Ratio as a new multidimensional biomarker in obese patients with liver steatosis undergoing VLEKT: results from a pilot study.
Balestra F, Donghia R, De Luca M et al.
Front Nutr·2026·Human·PubMed →
Combined resistance exercise and essential amino acid intake enhance follistatin/myostatin ratio and muscle fitness in older women: a randomized controlled trial.
Jeong D, Valentine RJ, Jeong H et al.
J Int Soc Sports Nutr·2026·Human·Muscle Recovery, Anti-Inflammatory·PubMed →
Higher serum follistatin levels are associated with increased vascular calcification in haemodialysis patients.
Liu C, Zhang A, Li Z
Front Endocrinol (Lausanne)·2026·Human·PubMed →
Adipo-Myokine Modulation in Obesity: Integrative Effects of Spinach Thylakoids and Functional Training in Men with Obesity: A Randomized Controlled Clinical Trial.
Razi O, Shafei A, Abdi M et al.
Nutrients·2026·Human·Weight Loss, Glycemic Control·PubMed →
Lorcaserin induces abdominal fat loss with associated improvements of the circulating metabolome/lipidome and no changes in the myostatin-activin-follistatin-IGF-1 axes: A 6-month long randomized placebo-controlled clinical trial.
Ramirez-Cisneros A, Gutierrez de Piñeres V, Tamayo-Torres CS et al.
Diabetes Obes Metab·2026·Human·GH Activity, Weight Loss·PubMed →
Effects of liraglutide treatment for 35-days on total and regional fat free, lean, and bone mass, and on the Myostatin-Activin-Follistatin-IGF-1 axes: a secondary analysis of a randomized placebo-controlled crossover study.
Gutierrez de Piñeres V, Ramirez-Cisneros A, Tamayo-Torres CS et al.
Diabetes Res Clin Pract·2026·Human·Weight Loss, GH Activity·PubMed →
Effect of exercise on hormonal responses in adolescents with obesity and leptin resistance: a randomized trial.
Jeong D, Valentine RJ, Park K et al.
Sci Rep·2026·Human·GH Activity·PubMed →
Effects of liraglutide treatment for 18 days on metabolic parameters, regional body composition and the myostatin-activin-follistatin-IGF-1 axis: Results from an exploratory, randomized, placebo-controlled, crossover study.
Gutierrez de Piñeres V, Tamayo-Torres CS, Ramirez-Cisneros A et al.
Diabetes Obes Metab·2026·Human·Glycemic Control, GH Activity·PubMed →
Knocking down FSTL1 reduces TGF-β2-induced trabecular meshwork fibrosis and ocular hypertension via inhibition of the Smad3 signaling pathway.
Wen L, Yang Y, Gao Y et al.
Exp Eye Res·2026·Animal·PubMed →
Follistatin drives AR-independent prostate cancer through BMP signaling inactivation and microenvironmental remodeling.
Shi X, Fan Z, Qu M et al.
Proc Natl Acad Sci U S A·2026·Animal·PubMed →
Deletion of protein FSTL3 unravels the role of activin signaling in regulating macrophage L-arginine metabolism and kidney injury.
Xing F, Xiang L, Yan J et al.
Kidney Int·2026·Animal·PubMed →
Prognostic Value of FST and Relevance to Immune Infiltration in Head and Neck Squamous Cell Carcinoma.
Song P, Wu TW, Wang JY et al.
World J Otorhinolaryngol Head Neck Surg·2026·Animal·PubMed →
Retraction: GDF8 promotes the cell invasiveness in human trophoblasts by upregulating the expression of follistatin-like 3 through the ALK5-SMAD2/3 signaling pathway.
Frontiers Editorial Office
Front Cell Dev Biol·2026·Animal·PubMed →
Grip strength as a systems biomarker of aging: neuromuscular junction constraints and biomarker decoupling in gene therapy.
Sewell PE, Jensen C
Front Aging·2026·Animal·PubMed →
Secreted Frizzled-Related Protein 2 (SFRP2) Induces Follistatin-Like 1 (FSTL1) to Regulate Dihydrotestosterone (DHT)-Induced Dermal Papilla Cell Mitochondrial Dysfunction and Senescence.
Huang Y, Bian Q, Shen Y et al.
Aging Cell·2026·Animal·Longevity·PubMed →
The Adipose-Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte-Derived Neurotrophic Factor for WAT Browning.
Jia XW, Liu JX, Wang RP et al.
Adv Sci (Weinh)·2026·Animal·PubMed →
Effects of thyroid hormones on muscle and bone in mice.
Nishikawa A, Kawao N, Mizukami Y et al.
Exp Clin Endocrinol Diabetes·2026·Animal·PubMed →
Follistatin Alleviates Vascular Dysfunction by Reducing Oxidative Stress and Promoting Browning in Perivascular Adipose Tissue.
Kuganathan A, Lu C, MacDonald M et al.
Hypertension·2026·Animal·PubMed →
The crystal structure of the activin B:Fst288 complex and computational insights into the broad antagonistic activity and specificity of follistatin.
Hok L, Walker RG, Howard JA et al.
J Biol Chem·2026·Animal·PubMed →
Melatoninergic Modulation of Benzene-Induced Pre-Leukemic Alterations in Rats: Effects of Melatonin, Agomelatine, and Luzindole : Short title: Melatoninergic Modulation in Benzene-Induced Pre-Leukemi.
M Hussein M Raouf M, Maulood IM, Marzany ZS
Galen Med J·2026·Animal·PubMed →
Fstl1 determines luminal size of mouse trachea through negative regulation of BMP4 signaling.
Jin Y, Zhang Y, Liu Y et al.
iScience·2026·Animal·PubMed →
Serum-Free Expanded Hair Follicle Mesenchymal Stem Cells Promote Cartilage Repair in a Murine Full-Thickness Defect Model.
Sun H, Gysel E, Larijani L et al.
Transplant Cell Ther·2026·Animal·PubMed →
Erratum for the Research Article "Follistatin gene delivery enhances muscle growth and strength in nonhuman primates".
Sci Transl Med·2026·Animal·PubMed →
Liver Endothelia Orchestrate MASH-Associated Macrophage Zonation Through FSTL1-ITGA4 Axis.
Sun L, Yue Z, Fang Z et al.
Adv Sci (Weinh)·2026·Animal·Liver Protection·PubMed →
Synergistic protective effects of melatonin and ascorbic acid against benzene-induced genotoxicity, oxidative stress, and activin A/follistatin dysregulation in a rat model of pre-leukemia.
Raouf MMHM, Maulood IM, Marzani ZS
J Toxicol Sci·2026·Animal·PubMed →
Intrafollicular activin-A, inhibin-B, and follistatin are associated with in vitro fertilization outcomes in subfertile women.
Karayiannis D, Tenta R, Kontogianni MD et al.
Hormones (Athens)·2026·Animal·PubMed →
Teneurins Are SPARCL1 Receptors.
Zhang X, Chen X, Miao Y et al.
bioRxiv·2026·Animal·PubMed →
ATF3/SOX11-regulated FST activates IGF1R-ERK/AKT-Sp1 signaling to sustain trigeminal neuropathic pain.
Ling YJ, Zhu B, Yao ZH et al.
Acta Pharmacol Sin·2026·Animal·PubMed →
Placental transcriptome analysis reveals BMI-dependent gene expression profiles in preeclampsia.
Duehring JA, Yu PT, Deihl TE et al.
Placenta·2026·Animal·Weight Loss·PubMed →
Correction: Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo-orchitis in mice.
Nicolas N, Michel V, Bhushan S et al.
Sci Rep·2026·Animal·PubMed →
Follistatin Mitigates Atherosclerosis Through Activation of Arginine Metabolism and Adipose Browning.
Dirakvand G, Pervin S, Villa B et al.
Cells·2026·Animal·Cardiovascular Risk·PubMed →
Alterations in systemic and skeletal muscle myostatin regulation are most prominent at disease onset and associate with muscle-related outcomes in idiopathic inflammatory myopathies.
Vernerová L, Lážnovská L, Baloun J et al.
Arthritis Res Ther·2026·Animal·Muscle Recovery·PubMed →
Elevated Serum Follistatin-Like Protein 1 Levels Correlate with Disease Activity and Severity in Behçet's Disease: A Case-Control Study.
Farrag S, Ibrahim Ismail NI, Abd El-Kader MG et al.
Mediterr J Rheumatol·2026·Animal·PubMed →
Marine-Derived Fucoidan Modulates Pathways Associated with Age-Related Macular Degeneration in Cellular and Zebrafish Models.
Shad HH, Dörschmann P, Hautmann SL et al.
Mar Drugs·2026·Animal·Anti-Inflammatory·PubMed →
Deletion of Tgf-β1 From CD206(+) M2 Macrophages Ameliorates Obesity-Induced Suppression of Myogenesis and AMPK Phosphorylation in Skeletal Muscle.
Bilal M, Anh LD, Phuong NQ et al.
J Cachexia Sarcopenia Muscle·2026·Animal·Muscle Recovery, Weight Loss·PubMed →
Cardiac rehabilitation influences serum myokine levels in patients after acute coronary syndrome: the randomised CARDIO-REH study.
Skrypnik D, Skrypnik K, Granell JC et al.
Sci Rep·2025·Human·PubMed →
The Role of Selected Myokines in the Development of Cardiovascular Diseases, and Their Involvement in Developing Heart Failure in Rheumatoid Arthritis Patients.
Kuna J, Chmielewski G, Jaśkiewicz Ł et al.
Int J Mol Sci·2025·Human·Cardiovascular Risk, Anti-Inflammatory·PubMed →
Plasma FSTL-1 as a noninvasive diagnostic biomarker for patients with advanced liver fibrosis.
Li W, Chi Y, Xiao X et al.
Hepatology·2025·Human·Liver Protection·PubMed →
Dynamic changes of systemic and local myokines in burn patients undergoing physiotherapy: A pilot prospective study.
Svecova M, Bakalar B, Vyklicka K et al.
Burns·2025·Human·Wound Healing, Muscle Recovery·PubMed →
Exploratory unsupervised machine learning of angiogenesis biomarkers in a phase II advanced cervical cancer trial of radiochemotherapy with or without neoadjuvant chemotherapy.
Arai RJ, da Costa TR, Bonadio RC et al.
Clinics (Sao Paulo)·2025·Human·PubMed →
FST Polymorphisms Associate with Musculoskeletal Traits and Modulate Exercise Response Differentially by Sex and Modality in Northern Han Chinese Adults.
Cao W, Gu Z, Fu R et al.
Genes (Basel)·2025·Human·Muscle Recovery·PubMed →
Changes in serum myostatin levels among patients with type C liver cirrhosis treated with direct-acting antivirals.
Suehiro T, Kozuru H, Matusmoto K et al.
Hepatol Res·2025·Human·PubMed →