Research Index

Degarelix Research Index

PSI surfaces 50 peer-reviewed studies on Degarelix, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.

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50 studies

Efficacy and safety of peptide radionuclide therapy with (177)Lu-DOTATATE in Japanese patients with advanced neuroendocrine neoplasm: a multicenter retrospective study (JON2203-N).

Okamoto K, Hijioka S, Kobayashi N et al.

J Gastroenterol·2026·Human·PubMed →

Pituitary dysfunction in trans-sellar encephalocele: a two-case report and a literature review.

Amano K, Seki Y, Koizumi S et al.

Endocr J·2026·Human·GH Activity·PubMed →

Clinical implications of aldosterone responsiveness to adrenocorticotropic hormone stimulation in two major subtypes of primary aldosteronism.

Watanabe D, Morimoto S, Morishima N et al.

Clin Exp Hypertens·2026·Animal·PubMed →

Prospective study of anamorelin in pancreatic cancer cachexia: Clinical and translational insights into response heterogeneity.

Matsukane R, Minami H, Fujimori N et al.

Clin Nutr·2026·Animal·Appetite Regulation·PubMed →

Reduced high-sensitivity C-reactive protein levels following weekly somapacitan in adults with growth hormone deficiency: a prospective pilot study.

Seki Y, Morimoto S, Ikemoto M et al.

J Endocrinol Invest·2025·Human·GH Activity·PubMed →

Efficacy and safety of endoscopic hemostasis with a self-assembling peptide solution in patients with colonic diverticular bleeding: a multicenter pilot study (with video).

Yamaguchi D, Tominaga N, Mori G et al.

Gastrointest Endosc·2025·Human·PubMed →

Isolated adrenocorticotropic hormone deficiency presenting with arthritis: A case report.

Yamashita Y, Sato S, Nii K et al.

Mod Rheumatol Case Rep·2025·Human·PubMed →

Ozone therapy and the role of the glutathione pathway.

Chirumbolo S, Franzini M, Tirelli U et al.

Inflammopharmacology·2025·Animal·Anti-Inflammatory·PubMed →

A case of gastric-localized juvenile polyposis syndrome with SMAD4 mosaic variant presenting as a slowly progressive phenotype.

Fukuya H, Sasaki T, Ihara E et al.

Clin J Gastroenterol·2025·Animal·PubMed →

Neoantigen peptide-pulsed dendritic cell vaccine therapy after surgical treatment of pancreatic cancer: a retrospective study.

Oyama K, Nakata K, Abe T et al.

Front Immunol·2025·Animal·PubMed →

Importance of rectal over colon status in ulcerative colitis remission: the role of microinflammation and mucosal barrier dysfunction in relapse.

Nishioka K, Ogino H, Ihara E et al.

J Gastroenterol·2025·Animal·GI Protection, Anti-Inflammatory·PubMed →

Elotuzumab-mediated ADCC with Th1-like Vγ9Vδ2 T cells to disrupt myeloma-osteoclast interaction.

Inoue Y, Tenshin H, Teramachi J et al.

Cancer Sci·2025·Animal·PubMed →

Polycystic ovary syndrome in a patient with type B insulin resistance syndrome can improve with glucocorticoid treatment: a case report and literature review.

Watanabe T, Okabe S, Sakamoto S

Endocr J·2023·Human·Glycemic Control·PubMed →

[Efficiency and safety of Prostatex in patients with chronic prostatitis/chronic pelvic pain syndrome. Results of the phase IV PRESTIGE trial].

Morozov AO, Vovdenko SV, Maltsagova PS et al.

Urologiia·2023·Human·PubMed →

Plasma Heparin Cofactor II Activity Is Inversely Associated with Hepatic Fibrosis of Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus.

Hara T, Uemoto R, Sekine A et al.

J Atheroscler Thromb·2023·Human·PubMed →

INFLUENCE OF ADDING ZINC ARGINYLE-GLYCINATE TO IMPROVE EFFICACY OF BIOREGULATORY PEPTIDES OF THE PROSTATE GLAND IN TREATMENT OF PATIENTS WITH IMPAIRED SPERM PARAMETERS.

Rybalov M, Borovets S, Petlenko S et al.

Georgian Med News·2022·Human·PubMed →

Rapid decrease in eGFR with concomitant use of tyrosine kinase inhibitors and renin-aldosterone-angiotensin system inhibitors in patients with chronic myelogenous leukemia.

Tsuda M, Hirata A, Tokunaga S et al.

Int J Hematol·2022·Human·PubMed →

Safety and efficacy of tirzepatide as an add-on to single oral antihyperglycaemic medication in patients with type 2 diabetes in Japan (SURPASS J-combo): a multicentre, randomised, open-label, parallel-group, phase 3 trial.

Kadowaki T, Chin R, Ozeki A et al.

Lancet Diabetes Endocrinol·2022·Human·PubMed →

Basal insulin requirement in patients with type 1 diabetes depends on the age and body mass index.

Mitsui Y, Kuroda A, Ishizu M et al.

J Diabetes Investig·2022·Human·Glycemic Control, Weight Loss·PubMed →

Plasma heparin cofactor II activity is inversely associated with albuminuria and its annual deterioration in patients with diabetes.

Hara T, Uemoto R, Sekine A et al.

J Diabetes Investig·2021·Human·Glycemic Control·PubMed →

Differential Health Effects on Inflammatory, Immunological and Stress Parameters in Professional Soccer Players and Sedentary Individuals after Consuming a Synbiotic. A Triple-Blinded, Randomized, Placebo-Controlled Pilot Study.

Quero CD, Manonelles P, Fernández M et al.

Nutrients·2021·Human·Anxiety & Mood, Neuroprotection, Immune Modulation, Sleep·PubMed →

Long-term safety and efficacy of lanreotide autogel in Japanese patients with neuroendocrine tumors: Final results of a phase II open-label extension study.

Ito T, Fujimori N, Honma Y et al.

Asia Pac J Clin Oncol·2021·Human·PubMed →

Insights into Effects/Risks of Chronic Hypergastrinemia and Lifelong PPI Treatment in Man Based on Studies of Patients with Zollinger-Ellison Syndrome.

Lee L, Ramos-Alvarez I, Ito T et al.

Int J Mol Sci·2019·Human·PubMed →

Differences in the Serum 4β-hydroxycholesterol Levels of Patients with Chronic Hepatitis C Virus (HCV) Infection: A Possible Impact on the Efficacy and Safety of Interferon (IFN)-free Treatment.

Hirayama T, Ikegami T, Honda A et al.

Intern Med·2018·Human·PubMed →

The Effective Treatment with Cyclosporine of a Ulcerative Colitis Patient with Concurrent Idiopathic Thrombocytopenic Purpura Who Subsequently Developed Spontaneous Pneumomediastinum.

Iwasa T, Nakamura K, Ihara E et al.

Intern Med·2017·Human·PubMed →

Phase II study of lanreotide autogel in Japanese patients with unresectable or metastatic well-differentiated neuroendocrine tumors.

Ito T, Honma Y, Hijioka S et al.

Invest New Drugs·2017·Human·PubMed →

Evaluation of circadian phenotypes utilizing fibroblasts from patients with circadian rhythm sleep disorders.

Hida A, Ohsawa Y, Kitamura S et al.

Transl Psychiatry·2017·Human·Tissue Remodeling, Sleep·PubMed →

Utility of chromogranin B compared with chromogranin A as a biomarker in Japanese patients with pancreatic neuroendocrine tumors.

Miki M, Ito T, Hijioka M et al.

Jpn J Clin Oncol·2017·Human·PubMed →

Japan Fracture Observational Study (JFOS): patient characteristics and interim data on the use of daily teriparatide in Japanese patients with osteoporosis.

Soen S, Fujiwara S, Takayanagi R et al.

Curr Med Res Opin·2015·Human·PubMed →

Comparative effectiveness and safety study of triple therapy with simeprevir or telaprevir for non-cirrhotic patients with chronic hepatitis C virus genotype 1b infection.

Ogawa E, Furusyo N, Kajiwara E et al.

J Gastroenterol Hepatol·2015·Human·PubMed →

Effectiveness of triple therapy with simeprevir for chronic hepatitis C genotype 1b patients with prior telaprevir failure.

Ogawa E, Furusyo N, Dohmen K et al.

J Viral Hepat·2015·Human·PubMed →

Analysis of chemotherapy-induced neutropenia and optimal timing for prophylactic use of G-CSF in B-cell non-Hodgkin lymphoma patients treated with R-CHOP.

Shikata H, Yakushijin Y, Yamanouchi J et al.

Int J Clin Oncol·2014·Human·PubMed →

Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia.

Miyazaki Y, Fujiwara H, Asai H et al.

Blood·2013·Human·Longevity·PubMed →

Phase II study of sunitinib in Japanese patients with unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumor.

Ito T, Okusaka T, Nishida T et al.

Invest New Drugs·2013·Human·PubMed →

Reduced arterial stiffness in patients with acromegaly: non-invasive assessment by the cardio-ankle vascular index (CAVI).

Matsuda Y, Kawate H, Matsuzaki C et al.

Endocr J·2013·Human·Glycemic Control, GH Activity·PubMed →

WT1 peptide therapy for a patient with chemotherapy-resistant salivary gland cancer.

Shirakata T, Oka Y, Nishida S et al.

Anticancer Res·2012·Human·PubMed →

[Pathogenetic characteristics of generalized parodontitis in elderly patients].

Malezhik MS, Pinelis IuI, Malezhik LP

Adv Gerontol·2011·Human·Longevity·PubMed →

Characteristics of pancreatic diabetes in patients with autoimmune pancreatitis.

Ito T, Nakamura T, Fujimori N et al.

J Dig Dis·2011·Human·PubMed →

Decrease in plasma brain natriuretic peptide level in the early phase after the start of carvedilol therapy is a novel predictor of long-term outcome in patients with chronic heart failure.

Fujimura M, Akaike M, Iwase T et al.

Acta Cardiol·2009·Human·PubMed →

[Efficacy of vitaprost forte in patients with prostatic adenoma].

Miller AM, Iaroshenko VP, Soroka PV et al.

Urologiia·2008·Human·Anti-Inflammatory·PubMed →

[Vitaprost forte efficacy in patients with prostatic adenoma].

Tkachuk VN, Tkachuk IN

Urologiia·2008·Human·PubMed →

Preparation of functionally preserved CD4+ CD25high regulatory T cells from leukapheresis products from ulcerative colitis patients, applicable to regulatory T-cell transfer therapy.

Sumida Y, Nakamura K, Kanayama K et al.

Cytotherapy·2008·Human·PubMed →

Case of a patient with Philadelphia-chromosome-positive acute lymphoblastic leukemia relapsed after myeloablative allogeneic hematopoietic stem cell transplantation treated successfully with imatinib and sequential donor lymphocyte infusions.

Yoshimitsu M, Fujiwara H, Ozaki A et al.

Int J Hematol·2008·Human·PubMed →

Investigation of hyperuricemia during pegylated-interferon-alpha2b plus ribavirin combination therapy in patients with chronic hepatitis C.

Yamashita N, Enjoji M, Kotoh K et al.

J Dig Dis·2008·Human·PubMed →

Daily nasal spray of hPTH(1-34) for 3 months increases bone mass in osteoporotic subjects: a pilot study.

Matsumoto T, Shiraki M, Hagino H et al.

Osteoporos Int·2006·Human·Bone Healing·PubMed →

Re-evaluation of antitumor effects of combination chemotherapy with interferon-alpha and 5-fluorouracil for advanced hepatocellular carcinoma.

Enjoji M, Morizono S, Kotoh K et al.

World J Gastroenterol·2005·Human·PubMed →

Induction of HM1.24 peptide-specific cytotoxic T lymphocytes by using peripheral-blood stem-cell harvests in patients with multiple myeloma.

Jalili A, Ozaki S, Hara T et al.

Blood·2005·Human·PubMed →

Successful treatment with nonmyeloablative allogeneic hematopoietic stem cell transplantation in a patient with acute myeloid leukemia complicated with pulmonary infection.

Choi I, Abe Y, Ohtsuka R et al.

Int J Hematol·2004·Human·PubMed →

High plasma heparin cofactor II activity is associated with reduced incidence of in-stent restenosis after percutaneous coronary intervention.

Takamori N, Azuma H, Kato M et al.

Circulation·2004·Human·PubMed →

Diurnal fluctuation of edema synchronized with plasma VEGF concentration in a patient with POEMS syndrome.

Endo I, Mitsui T, Nishino M et al.

Intern Med·2002·Human·Anti-Inflammatory·PubMed →