Research Index

Defensins Research Index

PSI surfaces 50 peer-reviewed studies on Defensins, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.

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50 studies

The efficacy and safety of Femoston combined with Baoqing granules for kidney Yin deficiency in perimenopausal women: a randomized, double-blind, placebo-controlled trial.

Li C, Lei HY, Wang RL et al.

Front Endocrinol (Lausanne)·2026·Human·PubMed →

Effects of ACSM guideline-based exercise on patients with lung cancer: a systematic review and meta-analysis.

Guo J, Wu B, Zhang Y et al.

Front Physiol·2026·Human·PubMed →

Case Report: Integrative management of refractory fibromyalgia with pulsed electromagnetic fields and ozone therapy: a case series.

Lara-Reyes JA, Aranda-Abreu GE, Cortijo-Palacios X et al.

Front Med (Lausanne)·2026·Human·PubMed →

Efficacy and safety of transcutaneous electrical acupoint stimulation and acupressure in alleviating chemotherapy-related adverse reactions in female patients with breast cancer: a randomized clinical trial.

Yuan J, Chu J, Hu X et al.

Front Oncol·2026·Human·PubMed →

Gender differences in sleep quality and its associated factors in patients with hypertension: a cross-sectional study.

Li H, Ching SM, Liong SF et al.

BMC Public Health·2026·Human·PubMed →

Impact of Prescribed and Self-Selected Music Interventions on Stress, Sleep, Heart Rate Variability, and Brain Connectivity in Surgeons Using 7-Tesla Functional Magnetic Resonance Imaging and Wearable Actigraphy: Multimodal Feasibility Randomized Controlled Trial.

Rui M, Brandt A, Moore L et al.

JMIR Form Res·2026·Human·Sleep, Anxiety & Mood·PubMed →

Effectiveness and Cost-Effectiveness of an App-Based Mindfulness Breast Care Program for Reducing Body Image Distress and Stigma Among Survivors of Breast Cancer: Randomized Controlled Trial.

Lin H, Zhong Y, Zheng S et al.

J Med Internet Res·2026·Human·PubMed →

Burden among participants with central disorders of hypersomnolence in six European countries.

Jönsson L, Kobelt G, Kallweit U et al.

Sleep Med·2026·Human·PubMed →

Psychological interventions for weight management of patients with obstructive sleep apnea syndrome: A systematic review.

Wang Y, He M, Tian Y et al.

Am J Otolaryngol·2026·Human·PubMed →

Asynchronous telerehabilitation in prehabilitation and postoperative recovery for colorectal cancer: A protocol for a randomized controlled trial.

Burgos-Bragado JM, Jiménez-Sánchez C, Brandín-de la Cruz N et al.

PLoS One·2026·Human·PubMed →

Effects of Bifidobacterium longum 1714 on low mood and related symptoms: A randomized, double-blind, placebo-controlled trial.

Seamans KM, Patterson E, Holz C et al.

Exp Clin Psychopharmacol·2026·Human·PubMed →

Effectiveness and Safety of Low-Sodium Oxybate in Participants with Narcolepsy: Primary Results from the DUET Study.

Schneider LD, Ruoff CM, Plante DT et al.

Neurol Ther·2026·Human·PubMed →

Application of Photostimulation Therapy in Cognitive Function of Alzheimer's Disease Patients: A Scoping Review.

Xu B, Wan H, Liu P et al.

Clin Interv Aging·2026·Human·Cognitive Enhancement·PubMed →

Differences in sleep spindles and polysomnography in humans: a meta-analysis on the influence of age, sex, and cognitive ability.

Campos-Beltrán D, Zhang S, Marshall L

Front Sleep·2026·Human·PubMed →

Effects of mindfulness yoga intervention on physical function, anxiety, inflammatory response, and relapse intention in methamphetamine addicts: a 24-week randomized controlled trial.

Chen SX, Lyu ZX, Hao ZJ et al.

Front Public Health·2026·Human·Anxiety & Mood, Anti-Inflammatory·PubMed →

A Nurse-driven Sleep Protocol for Inpatient Stroke Rehabilitation.

Buchanan K, Smith L, Miller N et al.

Rehabil Nurs·2026·Human·PubMed →

Functional near-infrared spectroscopy assessment of the effects of transcranial direct current stimulation combined with transcranial magnetic stimulation on dynamic functional networks in patients with chronic insomnia: randomised, double-blind, parallel-group, controlled clinical trial.

Zhou Q, Liu Z, Li C et al.

BMJ Ment Health·2026·Human·PubMed →

Prevent 6:1 trial: pI rotocol for a feasibility trial of a 6:1 intermittent diet for weight gain prevention in women at increased risk of breast cancer.

Kinsey L, French D, Howell S et al.

BMJ Open·2026·Human·Weight Loss·PubMed →

Patient and clinician reported outcomes of calcipotriol/betamethasone dipropionate PAD-cream for the treatment of adult patients with scalp psoriasis under real-world conditions: results from the prospective, non-interventional, multicentre PRO-SCALP study.

López Estebaranz JL, Bewley A, Pinter A et al.

Clin Exp Dermatol·2026·Human·PubMed →

Efficacy of multiple acupoint stimulation therapies for primary insomnia patients: a systematic review and network meta-analysis.

Wang Y, Jiang HL, Zhao JY et al.

Front Psychiatry·2026·Human·PubMed →

Clinical efficacy of five-element music therapy in alleviating psychological distress among patients undergoing maintenance hemodialysis: a multicenter, non-inferiority, randomized controlled trial.

Zhang B, Hao W, Cheng L et al.

Front Psychol·2026·Human·PubMed →

Liposomal Bupivacaine Infiltration and Postoperative Pain Outcomes in Lumbar Fusion: A Prospective Randomized Controlled Trial.

Zhang SJ, Lu X, Liu TX et al.

J Pain Res·2026·Human·PubMed →

Trigger Point Electrical Dry Needling with Different Waveforms Plus Intra-Articular Corticosteroid for Knee Osteoarthritis: A Prospective Randomized Controlled Trial.

Lin Y, Jia W, Liu C et al.

J Pain Res·2026·Human·PubMed →

Generative AI vs web search for patient education: a comparative evaluation of OSA information quality.

Hack S, Locatello LG, Boldes T et al.

J Clin Sleep Med·2026·Human·Sleep Apnea·PubMed →

[Impact of perioperative transcutaneous auricular vagus nerve stimulation on pain and sleep quality after glaucoma surgery].

Wang Y, Shen WJ, Du YJ et al.

Zhonghua Yi Xue Za Zhi·2026·Human·PubMed →

Hyperbaric oxygen combined with postauricular and intratympanic steroid injections in diabetic patients with severe or profound refractory sudden sensorineural hearing loss.

Li H, Zhao C, Zhang W et al.

Am J Otolaryngol·2026·Human·PubMed →

Chronic Kidney Disease-Associated Pruritus in Patients on Home Haemodialysis.

Nayak KK, Goh JX, Sud K et al.

Nephrology (Carlton)·2026·Human·PubMed →

Yoga for Patients Undergoing Thoracic Radiotherapy and Their Family Caregivers: Results of a Randomized Controlled Trial.

Milbury K, Chen A, Li Y et al.

JCO Oncol Pract·2026·Human·PubMed →

A Randomised, Double-Blind, Placebo-Controlled Trial of Probiotic and Postbiotic Strains in Healthy Adults with Self-Reported Anxiety: Effects on Mood, Vitality, Quality of Life and Perceived Stress.

Day R, Friedman D, Cardoso A et al.

Brain Sci·2026·Human·PubMed →

A Scoping Review of Exercise Oncology in the Primary Brain Tumor Patient-Caregiver Dyad.

Vo AH, Libmann M, Carson D et al.

Curr Oncol·2026·Human·PubMed →

Perioperative stellate ganglion block improves early postoperative sleep after gynecological laparoscopic surgery: a randomized controlled trial.

Yang Q, Yang X, Mu T et al.

Front Neurosci·2026·Human·PubMed →

Crisugabalin Combined with Acetyl-Levo-Carnitine for Diabetic Peripheral Neuropathic Pain: A Phase 2 Randomized Controlled Trial.

Fu L, Xu N, Shang J et al.

J Pain Res·2026·Human·PubMed →

Acupuncture with the Sancai Acupoint Matching Method for Primary Insomnia: A Randomized Controlled Trial.

Zhao N, Wang Q, Li L et al.

Nat Sci Sleep·2026·Human·PubMed →

Effect of enriched environment on postoperative sleep and recovery quality in patients undergoing laparoscopic surgery for colorectal cancer.

Zhang P, Jiang D, Deng H

Front Oncol·2026·Human·PubMed →

Impact of cladribine tablets on PROs in patients with MS: insights from the 1st interim analysis of the CLADFIT-MS study.

Borriello G, Chisari CG, Maimone D et al.

Front Neurol·2026·Human·PubMed →

The hidden burden of narcolepsy type 1: Discordance in psychobehavioral symptoms between patient self-reports and reports from close family members and friends.

Mazza S, Fort E, Martel N et al.

Sleep Med·2026·Human·PubMed →

Efficacy of adjunctive intermittent theta-burst stimulation on depressive and insomnia symptoms in elderly patients with depression and comorbid insomnia: A randomized, sham-controlled trial.

Zhou J, Zhu K, Wang Y et al.

J Affect Disord·2026·Human·PubMed →

Functional and Patient-reported Outcomes in the Atorvastatin versus Placebo Trial of Hemorrhagic Cerebral Cavernous Malformations: An Exploratory Study.

Sader G, Alcazar-Felix RJ, Jhaveri A et al.

Cerebrovasc Dis·2026·Human·PubMed →

Investigation of the effects of stress and quality of life in patients with obstructive sleep apnea syndrome.

Karakaya A, Şimşek N

Sleep Breath·2026·Human·PubMed →

Tildrakizumab Improves Disease Severity and Patient-Reported Outcomes in Moderate-to-Severe Chronic Plaque Psoriasis: A Prospective Real-World Study.

Facheris P, Piscazzi F, Fiorillo G et al.

Dermatol Ther (Heidelb)·2026·Human·PubMed →

Comparative Evaluation of Ashwagandha (Withania somnifera) Root Extract and Melatonin for Improving Sleep Quality in Adults: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study.

Movva N, Salve J, Wankhede K et al.

Clocks Sleep·2026·Human·PubMed →

The efficacy of transcutaneous auricular Vagus nerve stimulation in non-specific chronic neck pain: A pilot study.

Atici E, Torlak S, Sürenkök Ö et al.

J Back Musculoskelet Rehabil·2026·Human·PubMed →

Brief Prolonged Exposure Therapy for Posttraumatic Stress After Spinal Cord Injury: A Randomized Controlled Trial.

Powers MB, Douglas ME, Jones K et al.

Top Spinal Cord Inj Rehabil·2026·Human·PubMed →

Impact of competitive anxiety on mood, sleep, and physical activity levels in young Tunisian karate athletes: A multidimensional prospective observational study.

Belgacem A, Salem A, Yildiz M et al.

Medicine (Baltimore)·2026·Animal·PubMed →

Levodopa-accelerated frailty: a hypothesis for a cumulative iatrogenic burden in Parkinson's disease.

Skaaning C

Front Neurol·2026·Animal·PubMed →

New-onset constipation at acute stage after stroke: incidence, risk factors, and impact on stroke rehabilitation.

Lv Z, Fan S, Ma X et al.

Front Neurol·2026·Animal·PubMed →

Life's Essential 8 in Pregnancy and Time to Incident Cardiometabolic Disease Over 7 Years Follow-Up.

Francis EC, Patel S, Pande A et al.

medRxiv·2026·Animal·PubMed →

Sleep quality as a mediator between perceived stress and dry eye severity among Chinese nurses.

Ren J, Zhang X, Li J et al.

Front Public Health·2026·Animal·Anxiety & Mood·PubMed →

Tai Chi exercise improves sleep quality in older adults with mild insomnia by enhancing slow-wave activity during deep sleep: a 12-week randomized controlled trial.

Lyu M, Cheng J, Li J

Front Physiol·2026·Animal·PubMed →

Sleep quality assessment in hospitalized postoperative surgical patients: a COSMIN-based systematic review.

Nurhayati N, Waluyo A, Kariasa IM et al.

Front Sleep·2025·Human·PubMed →