Davunetide (NAP/AL-108) — Indexed Studies

Elevated Serum Telomerase Level and Peripheral Blood hTERT Gene Expression in Patients with Stable Coronary Artery Disease.

Ozmen C, Inandiklioglu N, Tepe O et al.

A novel polymorphism in the TERT gene is associated with lower survival in male patients with melanoma.

Rocca MS, Di Nisio A, Del Fiore P et al.

WRAP53 is Downregulated in Acute Myeloid Leukemia Patients and Positively Correlates With HTERT Expression.

Gadelha RB, Nogueira BMD, Machado CB et al.

Modulation of the clonal burden in patients with lower-risk myelodysplastic neoplasms treated with imetelstat.

Santini V, Zeidan AM, Van Eygen K et al.

An Anthocyanin- and Anti-Ageing Amino Acids-Enriched Pigmented Rice Innovation Promotes Healthy Ageing Through the Modulation of Telomere, Oxidative Stress and Inflammation Reduction: A Randomized Clinical Trial.

Wattanathorn J, Thukham-Mee W, Phuthong S et al.

Integrative diagnostic approach in a rare case of primary thyroid leiomyosarcoma with distant metastasis: a case report and literature review.

Li J, Wu B, Chen Z et al.

[TERTp mutation screening using digital droplet PCR of collection of 52 paired DNA samples from blood plasma and tumor tissue in patients with glioblastoma].

Hasanau TN, Pisarev EK, Sergeev AV et al.

Dynamics of Telomerase-Based PD-L1 Circulating Tumor Cells as a Longitudinal Biomarker for Treatment Response Prediction in Patients with Non-Small Cell Lung Cancer.

Sumiyoshi I, Togo S, Okabe T et al.

Tumor habitat analysis using multiparametric MRI as a noninvasive correlate of longitudinal changes in telomerase activity in recurrent IDH-wildtype glioblastoma.

Jeong SY, Lee J, Choi Y et al.

Glutamic Acid-Chelated Cobalt Stabilizes G-Quadruplexes and Selectively Suppresses Hepatocellular Carcinoma Growth.

Lin KH, Lin YJ, Hong YB et al.

PTC-Assisted Chemoselective S-Alkylation of 5-Mercapto-1,3,4-Oxadiazol Derivative: Multi-Target Anticancer via EGFR, Telomerase, and Thymidylate Synthase Inhibition With Apoptosis Induction.

Zakaria A, Al-Karmalawy AA, Hawas SS et al.

Carboxylesterase 2-Engineered Stem Cell Therapy Shows Superior Efficacy over Cytosine Deaminase in Castration-Resistant Prostate Cancer.

Kim JH, Song M, Lee SH et al.

Microwave-Assisted Propolis Extract Attenuates Oxidative-Stress- and Replicative Senescence via NRF2 and Wnt/β-Catenin-TERT Activation in Human Dermal Fibroblasts.

Shin S, Jang Y, Jeon K et al.

3,6'-Disinapoyl Sucrose from Polygalae Radix Exerts Anti-Aging Effects via Modification of Telomeres, SIRT1/p53/p21 Pathway, Oxidative Stress and Autophagy.

Wang J, Jiang T, Chen S et al.

Tenofovir Alafenamide Promotes Differentiation and Induces Apoptosis of AML Cells by Inhibiting Telomerase Reverse Transcriptase.

Lee JE, Jeon BE, Kwon CS et al.

Phosphodiesterase 5 Inhibitor Sildenafil Inhibits HPV(+) Cervical Cancer Cells and Cervical Cancer Stem Cells by Apoptotic Induction and Telomerase Activity Modulation.

Sarkar S, Saha A, DAS B et al.

P53-armed Oncolytic Adenovirus Enhances the Efficacy of PD-1 Blockade in Neuroblastoma by Inducing Immunogenic Cell Death.

Tani M, Tazawa H, Tanimoto T et al.

A Revealing Case of SHQ1-Related Neurodevelopmental Disorder: Expanding the Genotypic and Phenotypic Frontier.

Ly E, Lee M

Non-telomeric function deficiency of TERT enhances pressure overload-induced mouse cardiac remodeling by activation of CNBP-mediated THBS3/ITGB1 pathway.

Liu YY, Wang YC, Gong WY et al.

The Missing Piece: Functional Telomerase Restored in the Beetle Model.

Fajkus P, Štefanovie B, Závodník M et al.

Enhanced antitumor activity of atorvastatin and luteolin, with or without doxorubicin, in a solid Ehrlich carcinoma mouse model: modulation of ABC transporters, telomerase, and cancer stem cells.

Al-Ashmawy GM, El-Ashmawy NE, Hamada OB et al.

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma.

Sugawara M, Haruta M, Ohira M et al.

The telomerase reverse transcriptase-derived peptide GN11 alleviates glycolysis and cellular senescence in the fibrotic kidney by inhibiting the TGF-β1/Smad3/lncRNA Oip5-os1/miR-30c-5p/Rock2 axis.

Yang R, Zhang J, Feng X et al.

Effects of Bacopa monnieri herbal supplement on aging and neurocognitive functions, including neurophysiological assessments, in relation to constitution (Prakriti) in healthy adults: clinical trial protocol.

Pradeep HLNR, Perera PK, Waratenne PR et al.

DDX21 Links BRAF(V600E) and TERT to Promote Thyroid Cancer Progression.

Chen M, Jiang K, Zhang Q et al.

Cycloastragenol attenuates osteoarthritis by restoring chondrocyte senescence via the NRF2/NF-κB signaling axis.

Zhang S, Zou Y, Long J et al.

NRF2-TERT-ACSL4 pathway inhibits ferroptosis and regulates cytoskeletal dynamics to mitigate ovarian aging.

Chen Y, Zhang J, Cui S et al.

Protection of telomeres 1b safeguards the Arabidopsis genome by regulating ROS homeostasis.

Min JH, Castillo-González C, Barcenilla BB et al.

Modified hTERT treatment ameliorates pressure overload-induced heart failure.

Zhao Y, Bao X, Xiong W et al.

Deciduous pulp stem cell-derived extracellular vesicles stimulate the proliferation of cartilage progenitor cells via extracellular signal-regulated protein kinase 1/2 activation.

Murata S, Sonoda S, Kyumoto-Nakamura Y et al.

Prognostic stratification in hepatocellular carcinoma using a telomerase-related lncRNA signature derived from TCGA database.

Yang R, Xing L, Wang C et al.

Nanoparticle-based colorimetric biosensor for the detection of telomerase activity based on the peroxidase-mimicking activity of nanogold.

Hoang Uyen LT, Cam Duyen VT, Truong PL

A network-driven computational framework for identifying FDA-approved drug repurposing across heterogeneous brain cancers.

Prakash O

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome.

Pepke ML, Hansen SB, Limborg MT

SMARCAL1 is a candidate therapeutic target for ALT-positive tumors.

Taglialatela A, Lee J, Azeroglu B et al.

Shelterin Component TPP1 Drives Tumor Progression and Predicts Poor Prognosis in Hepatocellular Carcinoma.

Jang JE, Kim HS, Kim JS et al.

Effects of Light Spectrum and Intensity on Cellular Stress Responses in Baikal Whitefish and Its Hybrid Embryos: A Basis for Optimizing the Aquaculture Environment.

Sapozhnikova YP, Koroleva AG, Yakhnenko VM et al.

UBE3A-mediated mH2A1 Ubiquitination activates TERT transcription to promote senescence resistance in pancreatic cancer.

Ren L, Lu R, Fei X et al.

Intracellular DNA network assembly triggered by microRNA and telomerase for imaging-guided STING hyperactivation.

Cheng Y, Feng Y, Shuai L et al.

Ophiopogon japonicus-derived plant exosomes: a promising strategy for blocking the progression of diabetic vasculopathy to myocardial infarction.

Pan Y, Tan M, Li X et al.

Altered Carnitine Homeostasis Modulates Hyperosmolarity-Induced Mitochondrial Dysfunction and Lipotoxicity in Human Corneal Epithelial Cells.

Kontoh-Twumasi R, Aliste A, Scheid A et al.

Investigating the Telomerase Downregulatory Potential of Steroidal Drugs Following Pharmacophore-Based Rational; Computational and In Vitro Assessments.

Al-Karmalawy AA, Alabdali AYM, Yousef TA et al.

A homozygote mutation in RPA2 associated with bone marrow failure, immunodeficiency, and telomere biology disorder.

Simon AJ, Neustadter-Blackman M, Lev A et al.

A Novel Peptide, HS1002, Enhances Antitumor Activity via Dual Targeting of the GnRH Receptor and Human Telomerase Reverse Transcriptase in Prostate Cancer Cells.

Park JH, Lee JC, Sharma S et al.

Integrated stress response promotes acute liver failure by activating SETD7 and enhancing NLRP3 methylation.

Nie Z, Liu X, Zhang H et al.

Senescence markers in peripheral blood mononuclear cells in pediatric drug-resistant epilepsy.

Günbey C, Muratoğlu B, Özdemir C et al.

NPM1 phosphorylation-mediated telomere maintenance via stabilization of POLD3 in ALT-positive osteosarcoma: unraveling mechanisms and therapeutic opportunities.

Zhao R, Li T, Yang Q et al.

Extreme Kinetic Stability and RNase Resistance of Human Telomerase RNA G-Quadruplexes Overcome by DHX36 Helicase.

Luo Q, Zhang Y, Qian Y et al.

Comprehensive Characterization of Stem Cell Landscape Identifies Novel Stemness-Relevant Genes for Nasopharyngeal Carcinoma Therapy.

Xu D, Chen B, Shen Y et al.

Old Friends, New Faces in Endothelial Dysfunction and Senescence.

Ale-Agha N, Jakobs P, Rafflenbeul A et al.