Research Index

DAHK Peptide Research Index

PSI surfaces 50 peer-reviewed studies on DAHK Peptide, prioritized by evidence strength: human clinical research first, then animal studies. The full historical archive is linked below on PubMed.

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50 studies

Pilot study demonstrating safety and efficacy of intravenous allogeneic uterine-derived mesenchymal stromal cell therapy in cats with naturally occurring osteoarthritis.

Williams V, Mick L, Windsor R et al.

Front Vet Sci·2026·Human·PubMed →

Myeloma engraftment suppresses osteocytic ossification signatures rescued by loading in mice and reveals predictors of patient outcome.

Ziouti F, Azeem M, Rummler M et al.

Bone·2026·Human·PubMed →

Long-term safety of intravenous human umbilical cord blood-derived mesenchymal stem cell therapy in rheumatoid arthritis: a 5-year follow-up study.

Park EH, Kim MJ, Kang KS et al.

Stem Cells Transl Med·2026·Human·PubMed →

Anti-Inflammatory and Metabolic Effects of Fresh Versus Freeze-Dried Platelet-Rich Plasma on Equine Osteoarthritis in an Ex Vivo Cartilage-Synovium Explant Co-Culture System: A Pilot Study.

Duan S, Wang Z, Jia Y et al.

Vet Sci·2026·Human·PubMed →

Pilot Study of an Alpha-2-Macroglobulin-Enriched Plasma-Derived Orthobiologic Preparation in Sport Horses with Chronic Degenerative Joint Disease.

Gugliandolo E, Biondi V, De Luca M et al.

Vet Sci·2026·Human·PubMed →

Porous tibial tuberosity advancement without using flange for the treatment of cranial cruciate ligament rupture in dogs-a clinical pilot study.

García-González M, Martínez-Campos H, Ramos-Bou J et al.

Front Vet Sci·2026·Human·PubMed →

Intra-articular injection of allogeneic canine adipose-derived stem cell enriched secretome in dogs undergoing tibial plateau leveling osteotomy: a prospective double-blind and randomized pilot trial.

Carrera ALC, Minto BW, Alcântara BM et al.

Vet Res Commun·2026·Human·Osteoarthritis·PubMed →

Efficacy of bedinvetmab on pain, activity, and body composition in obese dogs with osteoarthritis: A randomized double-blind placebo-controlled trial.

Phongphuwanan A, Tabtieang SP, Thanaboonnipat C et al.

Vet World·2026·Human·PubMed →

Clinical Outcomes Following Intra-Articular Administration of Autologous Muscle-Derived Mesenchymal Stem Cells in Horses with Chronic Osteoarthritis: A Prospective Open-Label Study.

Serteyn D, Graide H, Ceusters J et al.

Animals (Basel)·2026·Human·PubMed →

REAC-based bioelectrical neuromodulation as a conservative strategy in canine cranial cruciate ligament rupture: a translational pilot study.

Sanna Passino E, Caggiu S, Fatima G et al.

BMC Vet Res·2026·Human·Tendon & Ligament·PubMed →

First-in-human and multicenter phase I study of OSCA therapy for knee osteoarthritis.

Suh DK, Lee SH, Bae Y et al.

Exp Mol Med·2026·Human·Osteoarthritis·PubMed →

Pulsed electromagnetic fields vs NSAID therapy in canine osteoarthritis: A randomised comparative pilot study.

Sassaroli S, Dini F, Sisti V et al.

Vet Med (Praha)·2026·Human·PubMed →

Evaluation for radiographic changes in the coxofemoral joint and proximal femur following intramedullary stabilisation of diaphyseal femoral fractures using angle-stable interlocking nails in skeletally immature patients.

Meneghetti LM, O'Neill SR, Perry KL

J Small Anim Pract·2026·Human·PubMed →

Plasma concentrations following oral administration of two different forms of resveratrol in horses.

Mochal-King C, Strunk R, Paul L

J Equine Vet Sci·2026·Human·PubMed →

Vascular Complication After Revision of Total Knee Arthroplasty (R-TKA): A Case of Popliteal Branch Pseudoaneurysm Successfully Treated with Embolization-A Case Report and Mini Review of the Literature.

Zalewa K, Piech P, Nieoczym K et al.

J Clin Med·2026·Human·PubMed →

Long term safety and efficacy of a functionalized nanogel with endothelin-1 and bradykinin receptor antagonist peptides for treatment of osteoarthritis of the metacarpophalangeal and distal interphalangeal joints in horses: a descriptive clinical pilot study.

Terlinden A, Jacquet S, Manivong S et al.

BMC Vet Res·2026·Human·Osteoarthritis·PubMed →

Evaluation of intra-articular injection of collagen-elastin hydrogel microparticles for managing osteoarthritis-associated elbow pain in dogs: a double-blind, positive-controlled clinical trial.

Castro G, Elam LH, Duerr FM

Front Vet Sci·2026·Human·PubMed →

Effects of Extracorporeal Shockwave Therapy on Pain and Mobility in Client-Owned Dogs with Refractory Elbow and Stifle Osteoarthritis: A Randomized Double-Blinded Trial.

Klein A, Winkler EV, Zablotski Y et al.

Animals (Basel)·2026·Human·PubMed →

A noninferiority trial evaluating the efficacy of bedinvetmab compared to grapiprant for osteoarthritis-pain in dogs using force plate gait analysis.

Enomoto M, Buslinger L, Thonen-Fleck C et al.

Sci Rep·2026·Human·Osteoarthritis·PubMed →

Effects of pentosan polysulfate sodium on joint structure and function out to six months in naturally-occurring canine osteoarthritis.

Stapledon CJM, Krishnan R, Peat RA et al.

PLoS One·2026·Human·Osteoarthritis·PubMed →

Pharmacokinetics of Buccally Administered Cannabidiol and Oral Carprofen During Single- and Repeated-Dose Administration in Dogs.

Vake T, Tomsič K, Žgank Ž et al.

J Vet Pharmacol Ther·2026·Animal·PubMed →

Dose-dependent histopathological and immunohistochemical effects of metformin in experimental osteoarthritis.

Koca N, Nacir B, Yumuşak N et al.

Clin Rheumatol·2026·Animal·PubMed →

Concurrent Alterations in Selected mRNAs and miR-30 Family Members in Canine Osteoarthritic Joint Tissues.

Guelfi G, Ratto VF, Capaccia C et al.

Biomedicines·2026·Animal·PubMed →

Diagnostic Performance of Digital Tomosynthesis for Detecting Osteophytes and Subchondral Bone Changes in the Equine Distal Interphalangeal and Metacarpophalangeal Joints.

Hahn A, Valdés Vázquez M, Manso-Díaz G et al.

Animals (Basel)·2026·Animal·PubMed →

Zlig ligament reconstruction versus tibial plateau leveling osteotomy for cranial cruciate ligament rupture in dogs: a prospective controlled study.

Chwatal S, Volz F, Kornmayer M et al.

Front Vet Sci·2026·Animal·PubMed →

Combined tibial plateau leveling osteotomy and autologous conditioned serum for functional recovery and delayed osteoarthritis progression in dogs with cranial cruciate ligament rupture.

Ji C, Gao G, Deng G

Front Vet Sci·2026·Animal·PubMed →

Chronic joint pain drives sex-specific changes in hippocampal glutamatergic signaling and sleep.

Stepanova V, Lefevre N, Villegas AL et al.

NPJ Biomed Innov·2026·Animal·PubMed →

Mechanobiology of the osteochondral unit using advanced imaging in preclinical osteoarthritis models.

Durongbhan P, Evans LA, Sharma A et al.

Osteoarthr Imaging·2026·Animal·PubMed →

Synthesis, characterisation, and in vitro assessment of hyaluronic acid-coated solid lipid nanoparticles entrapping dexamethasone palmitate designed for intra-articular administration.

Zhang J, Khandelia R, Hogg B et al.

Front Drug Deliv·2026·Animal·PubMed →

Anti-Inflammatory Role of Exopolysaccharides in Osteoarthritis via Modulation of Redox and Inflammatory/Catabolic Signaling Networks.

Elmetwalli A, Elsayed A, Ahmed El-Sakka S et al.

Appl Biochem Biotechnol·2026·Animal·PubMed →

Therapeutic Potential of Intra-Articular Delivery of Allogeneic Dedifferentiated Fat Cells in a Canine Monoiodoacetate-Induced Knee Osteoarthritis Model.

Nakano R, Seki A, Sugiya H

Cells·2026·Animal·Osteoarthritis·PubMed →

The Potential of Selective COX-2 Inhibitor Mavacoxib for Extended Analgesia in Sheep Husbandry.

Fioretto O, Metcalf L, Lomax S

Animals (Basel)·2026·Animal·PubMed →

Escin attenuates osteoarthritis via suppressing fibroblast-like synoviocytes Jun-promoted synovial inflammation and osteoclast differentiation.

Yuan Y, Sun Q, Hui T et al.

Bone·2026·Animal·Osteoarthritis, Anti-Inflammatory, Tissue Remodeling·PubMed →

Single-cell sequencing reveals synovial fluid γδ T-cell expansion in equine experimental osteoarthritis.

Ammons D, Chow L, Goodrich L et al.

Am J Vet Res·2026·Animal·PubMed →

Dynamic Compression Reveals Donor-Age-Associated Inflammaging in Human Mesenchymal Stromal Cell Spheroids.

Hoang TTT, Griffin KH, Mierswa S et al.

ACS Appl Mater Interfaces·2026·Animal·PubMed →

The inhibition of lactate/Gpr81 signalling driven by moderate-intensity continuous training protects against osteoarthritis.

Sun P, Guo Y, Xue A et al.

Exp Mol Med·2026·Animal·PubMed →

Atypical radiographic changes seen in dogs treated with bedinvetmab (Librela).

Budsberg SC, Clements DN, Regan DP et al.

J Am Vet Med Assoc·2026·Animal·PubMed →

Successful outcome of open distal interphalangeal joint luxation in equids treated by surgical debridement without internal implants.

Ferrari LC, Apolonio EVP, de Oliveira-Gonçalves SL et al.

Vet Res Commun·2026·Animal·PubMed →

Biopharmaceutical Characterization of Grapiprant Within the BCS Framework Under Canine-Relevant Conditions: Solubility and Caco-2 Permeability Assessment.

Wen Z, Sun X, Chen S et al.

Pharmaceutics·2026·Animal·PubMed →

Alpha-2-Macroglobulin-Enriched Plasma Modulates Inflammatory and Proteolytic Pathways in Experimental Equine Musculoskeletal Models.

Gugliandolo E, Franco GA, Biondi V et al.

Animals (Basel)·2026·Animal·PubMed →

Investigation into the Short-Term Effects of Intra-Articular Allogenic PRP in the Equine LPS Model of Joint Inflammation: A Randomised Control Trial.

Duggan MJS, Kearney C, Del Rincon A et al.

Animals (Basel)·2026·Animal·PubMed →

Neosaxitoxin Downregulates Inflammation in an Equine In Vivo Model of Osteoarthritis.

Dörner C, Lagos N, Oyaneder L et al.

Biomolecules·2026·Animal·Osteoarthritis, Anti-Inflammatory·PubMed →

Effects of Intra-Articular Administration of High-Molecular-Weight Linear Hyaluronic Acid on Synovial Fluid Characteristics and Joint Environment.

Ribeiro MDS, Altheman VG, Alexandre VF et al.

Antioxidants (Basel)·2026·Animal·PubMed →

Inhibition of cyclin-dependent kinase 8 modulates chondrocyte transition to hypertrophy and provides in vivo protection against spontaneous osteoarthritis.

Wells LM, Keen JAC, Sharma A et al.

Bone Res·2026·Animal·Osteoarthritis·PubMed →

Development and validation of a Quality of Life and Treatment Satisfaction measure in feline osteoarthritis.

Gildea E, Thompson J, Cook A et al.

Front Vet Sci·2026·Animal·PubMed →

Cord blood mesenchymal stromal cells combined with hyaluronic acid show symptom-modifying and potential disease-modifying effects in an equine osteoarthritis fetlock chip model.

Luque RM, Mortagy N, McCorkell TC et al.

Front Vet Sci·2026·Animal·PubMed →

Trochlear Ridge Prosthetic Replacement Surgery in 20 Dogs with Medial Patellar Luxation: Clinical and Radiographic Findings.

MacEwan IR, Hankin EJ, Barbur LA

Vet Comp Orthop Traumatol·2026·Animal·PubMed →

Utility of Infrared Thermography in Dogs with Osteoarthritis.

Lewis MJ, Kawecki-Wright E, Hall AL et al.

Animals (Basel)·2026·Animal·PubMed →

A randomized, double-blind, controlled study on the efficacy of an oral dietary supplement containing fish oil, ASU and phytotherapeutic extracts in canine osteoarthritis.

Palumbo Piccionello A, Riccio V, Sassaroli S et al.

Front Vet Sci·2025·Human·PubMed →

Efficacy, pharmacokinetics and safety of liposomal synthetic cannabidiol injected subcutaneously in dogs: a randomized, blinded, placebo-controlled, crossover clinical trial.

Shilo-Benjamini Y, Milgram J, Lavy E et al.

Front Vet Sci·2025·Human·PubMed →